Schistosomiasis cerebralis can be clinically divided into two types, acute and chronic, and their respective clinical manifestations are: ① Acute type: clinically rare, often outbreaks of disease, with meningoencephalitis as the main manifestations, such as fever, headache, ambiguity, lethargy, coma, hemiplegia, partial or generalized epileptic seizures, etc.; ② Chronic type: usually occurs in the first 3-6 months after the infection, and the longest case can be up to 1-2 years, with chronic schistosomiasis as the main manifestation, because of the eggs of the worm caused by granuloma formation, so the clinical manifestations are often similar to the tumor. Schistosoma encephalopathy is the main manifestation, because the worm eggs cause granuloma formation, so the clinical manifestations are often similar to the tumor, symptoms of increased intracranial pressure, such as vomiting, headache, and focal neurological signs of damage, partial or generalized epileptic seizures are also very common, spinal cord granuloma formation can cause acute and incomplete transverse spinal cord damage to the symptoms and signs.