The "Daily Materia Medica" written by Wu Rui, a famous doctor in the Yuan Dynasty, said that shiitake mushrooms "replenish qi, relieve hunger, and treat wind and blood". It is a health food that makes people energetic and can promote blood circulation in the human body.

Shiitake mushrooms are commonly used among Chinese people to treat smallpox and measles in children.

Shiitake mushrooms contain ergosterol, which is rare in general food. After being absorbed by the body, it can be converted into vitamin D2, thereby preventing and treating rickets and anemia.

Dr. Crane of the University of Michigan in the United States confirmed that the spores of shiitake mushrooms contain a betel-nut-shaped particle-like inhibitory substance that has a good effect on treating influenza.

Shiitake mushrooms also contain adenine, an ingredient that can lower cholesterol. Dr. Suzuki of Japan's National Institute of Nutrition conducted a clinical trial on 480 people. Each person ate 9 grams of shiitake mushrooms per day. After one week, the cholesterol of female students dropped by 6-12 on average, and that of the elderly group dropped by 7-15.

It is believed that for patients with arteriosclerosis, hypertension, acute and chronic nephritis, proteinuria, and diabetes caused by excessive cholesterol, shiitake mushrooms are undoubtedly a good food therapy.

Professor Mangu of Nagoya University discovered that the special amino acids contained in shiitake mushrooms can significantly reduce patients' urinary protein.

Clinical data show that shiitake mushrooms can treat a variety of kidney diseases without side effects.