1. The stability of the two is different at room temperature

Levofloxacin hydrochloride belongs to the hydrochloride category. Its ingredients are relatively stable and not prone to denaturation. Therefore, the production process is relatively simple and the production The cost is lower and the price is cheaper. Levofloxacin has high activity and is easy to decompose. It is not easy to store at room temperature and its ingredients are unstable. Therefore, the production process is complicated and the production cost is high, so the price is relatively expensive.

2. Side effects are different

The side effects of Levofloxacin Hydrochloride Tablets are smaller than ofloxacin, and the effect of Levofloxacin Hydrochloride Tablets is more significant than ofloxacin. In fact, Levofloxacin Hydrochloride Tablets are quinolones. The third generation of drugs, levofluoride is a relatively safe drug. It mainly prevents and treats infections caused by intestinal bacteria, such as urethritis, diarrhea, and pyelonephritis. Most people are not allergic.

Extended information:

It is the L-body of ofloxacin. Its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit bacterial DNA gyrase. (bacterial topoisomerase II) activity, hindering bacterial DNA replication.

It has the characteristics of broad antibacterial spectrum and strong antibacterial effect. Most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, and Pseudomonas aeruginosa Gram-negative bacteria such as Mononas aeruginosa, Haemophilus influenzae, and Neisseria gonorrhoeae have strong antibacterial activity.

It also has good antibacterial effects on some methicillin-sensitive Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococcus and other gram-positive bacteria, as well as Legionella, Mycoplasma, and Chlamydia, but it has good antibacterial effects on anaerobics. Aerobic bacteria and enterococci are less effective.

Reference materials: Baidu Encyclopedia - Levofloxacin Hydrochloride Baidu Encyclopedia - Ofloxacin