2. Vaccination with COVID-19 vaccine during a cold is not only easy to aggravate the cold symptoms, but also may induce or aggravate the adverse reaction of re-vaccination, and even lead to vaccination failure. If you take cold medicine during a cold, it will easily affect the vaccination effect of COVID-19 vaccine. When there are cold symptoms such as fever, cough, sneezing and runny nose, it is recommended to pay attention to rest, drink more warm water and take active treatment measures. Vaccinate with COVID-19 vaccine after cold recovery. It is recommended to observe for half an hour after inoculation and leave the inoculation site after no abnormality.