A, what is progesterone

1, progesterone (progesterone)

Also known as progesterone hormone, luteinizing hormone, is the ovary secretion of biological activity of the main progesterone. Before ovulation, the amount of progesterone hormone produced per day is 2-3mg, mainly from the ovary.

2, to protect the female endometrium

After ovulation, it rises to 20~30mg per day, the vast majority of which is secreted by the corpus luteum in the ovary. Progesterone can protect women's uterine lining, during a woman's pregnancy, progesterone hormone can give the early growth and development of the fetus to provide support and protection, and can play a certain calming effect on the uterus.

3, progesterone is a female hormone

In addition, progesterone hormone and estrogen are inextricably linked, and both are quite important female hormones. The role of estrogen is mainly to promote the development of female secondary sexual characteristics, and progesterone hormone is based on the role of estrogen, to further promote the development of secondary sexual characteristics, there is a synergistic effect between the two.

4, clinical use

Clinically, progesterone is commonly used in the treatment of miscarriage and habitual abortion, premenstrual tension syndrome, anovulatory dysmenorrhea and anovulatory amenorrhea and other diseases. Progesterone is a prescription drug and also has certain side effects, and needs to be used under the guidance of a doctor. Progesterone is available in oral and injectable dosage forms.

5, benefits to women

Progesterone has two forms of capsules and injections, in the injection of flavonoids, this is used properly, the effect will be very good. Such as triad hormone injection: a light yellow clear oily liquid, containing 12.5mg of progesterone, the use of similar compound progesterone injection, mainly used for menstrual irregularities, the only withdrawal of bleeding is less; also used for menopausal syndromes and withdrawal of milk and so on. Progesterone has a very important significance for female pregnancy, by affecting the stimulation of estrogen on the endometrium to affect menstruation. At the same time it also has other aspects of the role of progesterone in the late menstrual period to promote the growth of glands in the uterine mucosa, endothelial thickening, for the implantation of the fertilized egg in preparation for the low progesterone will be delayed menstruation.

Second, progesterone pharmacology

1, make the embryo safe growth

In the second half of the menstrual cycle to promote the growth of endometrial glands, uterine congestion, thickening of the lining, for the implantation of fertilized eggs ready, and to reduce the uterine excitability, inhibit the activity, relaxation of the smooth muscle, so that the embryo is safe growth.

2, so that the full development of the breast

In and estrogen *** with the action, promote the development of mammary lobules and glands, so that the full development of the breast, in preparation for lactation.

3, inhibit the role of ovulation

To make the cervix closed, mucus reduced and thickened, and make it difficult for sperm to penetrate; large doses through the hypothalamus of the negative feedback, inhibit the secretion of pituitary gonadotropins, resulting in the inhibition of ovulation.

4, in favor of pregnant eggs and embryonic development

After ovulation, on the basis of hormone action, so that the endometrium continues to thicken, congestion, glandular hyperplasia and branching, from the proliferative phase to secretion phase, in favor of pregnant eggs and embryonic development.

5, inhibit uterine contraction

And reduce the sensitivity of the uterus to oxytocin, so that the fetus grows safely.

6. Competitively counteracting aldosterone

thereby promoting the excretion of Na and Cl and diuresis.

Three, clinical application

1, first treatment before pregnancy

If the progesterone level is found to be substandard before pregnancy, it can be treated before pregnancy. For women, progesterone is a necessary substance to maintain normal menstrual patterns. If you find a low level of progesterone before you prepare for pregnancy, it is best to go to the hospital for a detailed examination and cooperate with the doctor's guidance and active treatment.

2, through dietary therapy

Pregnant women with low progesterone levels can supplement their diets with soy isoflavones and vitamin E to help increase progesterone levels, such as kiwis, strawberries and other good food.

3, drugs to supplement progesterone

If women have low levels of progesterone, you can also directly through the drug to supplement, taking drugs or injections can be. If the injection to supplement progesterone, about 10 days will be able to reach the normal level, if you take drugs, need to be based on the physical condition of the pregnant woman to decide to take the dose and time. During this period the pregnant woman should go to the hospital in time and cooperate with the doctor to regulate the body.

4, if necessary, to give up birth control

If a woman has a progesterone level of less than 15 ng / ml phenomenon, and after the examination found that there is no fetal heart, then basically to give up birth control. This situation is mostly due to abnormal development of the fetus, so if you continue to protect the fetus may still be miscarriage, fetal malformation and other situations.

5, other measures

Pregnant women with low progesterone should pay attention to their daily routine and diet, to ensure enough sleep, more quiet, a reasonable combination of meals, more nutrition.