The main symptoms of vulvar leukoplakia are that the color of vulvar skin becomes lighter, itching and scratching lead to vulvar ulcer. With the aggravation of the disease, the vulvar skin becomes thicker, rougher and harder, and more seriously, the skin shrinks and becomes thinner, and cracks and adhesions appear. The skin in the lesion area will also have keratinization and hyperplasia, and the vulva skin will have a slight hypopigmentation, with a light color and a small white papule-like appearance. If the local skin keratinization and hyperplasia are very serious, the keratinized layer will fall off repeatedly with color loss. Components of the glue layer, which can promote cell division and root development.
Leukoplakia vulvae is a skin disease characterized by atrophy and thinning of vulva and perianal skin. Although the cause is unknown, it has a family genetic history. Some scholars have found that people with this disease usually have autoimmune diseases such as alopecia areata, vitiligo, hyperthyroidism or hypothyroidism, which shows that this disease is related to autoimmune.