Oral poisoning: Early symptoms include nausea and vomiting, burning pain in the upper abdomen, or vomiting of coffee and bloody stool, as well as insomnia, headache, tinnitus and fidgeting. In severe cases, delirium, muscle tremor, convulsion, persistent convulsion, coma and other nervous system excitement symptoms appear. In the future, it will be manifested as respiratory failure, decreased blood pressure and arrhythmia. Proteinuria and fever may also occur.

Injection poisoning: first, symptoms of cardiovascular system, such as arrhythmia, blood pressure drop and even shock; The main causes of poisoning death are persistent convulsion, respiratory and circulatory failure and ventricular fibrillation. Patients with oral poisoning should immediately induce vomiting, routine gastric lavage, high colon lavage after 4 hours, taking laxatives at the same time, and infusion of diuretics to promote the excretion of poisons. ? Neostigmine 0.5 mg ~ 1 mg, intramuscular injection, 1 time, 20 ~ 30 minutes. Symptomatic treatment: according to the clinical manifestations, routine treatment is given, such as lowering blood pressure, infusion shock, increasing pressure to prevent shock and maintaining water-electrolyte balance. During convulsion, diazepam 5 mg ~ 10 mg can be injected intravenously to control symptoms, and artificial hibernation is needed. Mechanical ventilation should be given when there is respiratory failure, and dehydrating agent should be used when there is brain edema. During the treatment, ephedrine, caffeine, nikethamide, adrenaline and anesthetics (morphine, pethidine, etc. ) should be avoided to avoid aggravating the toxicity of aminophylline.