This will have a bad effect. Generally speaking, the medicine has a certain effect when it is in it, but it has no effect when it is discharged. Therefore, as long as it is enema, there will be a feeling of wanting to defecate. What you need at this time is to endure and not rush to discharge the medicine, so that you will know that it is caused by the medicine and it will pass. So the effect of treatment in vivo will be better.