In the examination of liver function, alanine aminotransferase is an index to reflect liver cell injury, while aspartate aminotransferase is a standard to reflect liver cell necrosis. It is very accurate for the detection of liver cirrhosis, liver fibrosis and liver cancer. It can be combined with alanine aminotransferase to reflect the status of liver function. For example, patients with cirrhosis or early cirrhosis whose ratio of alanine aminotransferase to aspartate aminotransferase is lower than 1.0.

Many literatures report that AST/ALT ratio is helpful to judge the degree of liver disease and has certain significance for diagnosis. ① AST/AST

In the liver function test, the high aspartate aminotransferase is not necessarily caused by hepatitis. Because drinking, fatigue, staying up late, strenuous exercise and drugs may all cause high aspartate aminotransferase, it is not necessary to be too nervous when aspartate aminotransferase is high. Need to go to a regular hospital for diagnosis.

In physical examination, aspartate aminotransferase is often high, which many people don't understand.

Transaminase is an enzyme that catalyzes the transfer of amino groups between amino acids and ketoacids. It is widely distributed in animals, plant tissues and microorganisms, and has a high content in animal tissues such as heart muscle, brain, liver and kidney, mung bean sprouts, etc. There are many kinds of α -amino acids, except lysine and threonine, which can participate in transamination and have their own specific transaminase. Among them, alanine aminotransferase (GPT) and aspartate aminotransferase (GOT) are the most important.

The high level of aspartate aminotransferase indicates the existence of hepatocyte injury, which is common in various hepatobiliary diseases, such as hepatitis B, liver cirrhosis, fatty liver and alcoholic hepatitis. However, some external factors can also temporarily increase aspartate aminotransferase, such as exercise, diet, drinking, staying up late, and drugs (anti-inflammatory drugs are antibiotics, and cold drugs are not anti-inflammatory, so we should distinguish them, but both cold drugs and anti-inflammatory drugs may cause aspartate aminotransferase to increase). These situations should be ruled out and checked again. If the aspartate aminotransferase continues to rise, it is necessary to do further examination, such as half-test hepatitis B, determine the reason for the high aspartate aminotransferase, and give symptomatic treatment.