Crocus sativus, also known as Crocus sativus and Crocus sativus, has sedative, expectorant and spasmolytic effects, and can be used to treat gastropathy, menstruation, measles, fever, jaundice, hepatosplenomegaly, etc. Safflower, also known as grass safflower, has the effects of promoting blood circulation, dredging menstruation, removing blood stasis and relieving pain, and is mostly used for amenorrhea, dysmenorrhea, lochia, abdominal lump, traumatic injury and so on. The two cannot be substituted for each other. I hope it helps you.