Pattern Alias Baibei, Niu Stem, Foot Stirrup, Iron Niu Kexi, Du Niu Kexi, Huai Niu Kexi, Huai Xi, Zhen Xi, Huai Kexi, Tu Niu Kexi, Huai Niu Kexi, Red Niu Kexi, Niu Knocking Kexi, Niu Kexi, Niu Gai Kexi, Sticky Grass Sub-root, Niu Armpit Knees, Wild Niu Charging Kexi, Elderly Bone Dane, Niu Gai Kexi Tou
Hanyu Pinyin NIU XI
Latin Botanical and Animal Mineral Names Achyranthes bidentata Bl.
Plant Meridian Liver; Kidney Meridian
Effects nourishing the liver and kidney; strengthening the tendons and bones; invigorating blood circulation and opening up the channels; inducing the enemy's (fire) downward movement; diuretic and diaphoretic
Family Classification Amaranthaceae
Latin Name Radix Achyranthis Bidentatae
Soreness of the waist and knees; impotence and weakness of the lower limbs; blood stagnation; dysmenorrhea; postpartum blood stasis and abdominal pain; obstruction in the abdomen; impediment in the abdomen; impediment in the uterus; feverish drenching; bloody drenching; bruises; carbuncle, swollen and malignant sores; sore throat
Efficacy ClassificationExpeling wind; activating blood circulation to dispel blood stasis
Taste Bitter; Sour; Flat
Basic Origin of the Herbs The root of Radix Achyranthis Bidentatae is from the family of Amaranthaceae.
Use and dosage Internal use: decoction, 5-15g; or soaked in wine; or into pills, bulk. External use: appropriate amount, pounded compress; pounded juice drops nose; or powdered sprinkle into the teeth. [edit paragraph] Pharmacological research Pharmacological effects
1. Protein anabolic effect
Ecdysterone contained in hyssop has a strong protein synthesis promotion effect. Experiments to mice gastric or intraperitoneal injection of 1 time ecdysterone 2 hours after the mouse liver cell nuclei, mitochondria and microsomes in the amino acid precursors into the increase in 4 hours after the effect is stronger. Enhanced protein synthesis was also seen in the kidney, but returned to its original level after 4 hours. Sucrose density-like centrifugal analysis showed that administered blood RNA had a 2-fold casting activity compared to control blood, suggesting that the protein synthesizing effect of ecdysterone was accompanied by at least a promotion of m-RNA synthesis. When lactating male mice were given ecdysterone continuously for 60 days, their body weight increased rapidly, the level of liver and kidney protein synthesis also increased, and liver tissue examination showed that hepatocyte hyperfunction was manifested.
2. Anti-inflammatory and analgesic effects
2.1. on croton oil ear swelling mice:
Take 30 mice, randomly divided into three groups, the experimental group was injected with 0.5 ml/20 g of hyssop, and the control group was injected with saline, the results of the hyssop has a significant inhibitory effect on croton oily ear swelling and the effect increases with the increase in dose.
2.2. Effect on formaldehyde-based rat foot-plantar swelling:
Take 20 healthy rats, randomly divided into two groups, subcutaneous injection of 2.5% formaldehyde 0.1ml in the left and right metatarsals to cause inflammation, and the left and right feet as their own control. Intraperitoneal injection of hyssop 16.6ml/(kg.day), the results of the experimental group and the control group has a significant difference (P<0.05.
2.3. effect on acetic acid thermophilic body reaction in mice mice orally wai hyssop decoction has a highly significant analgesic effect.
3.Effects on cardiovascular system
3.1.Effects on the heart: the alcoholic extract of hyssop has a certain inhibitory effect on the isolated frog heart, anesthetized cats, and the water decoction has a more pronounced effect on the myocardium of anesthetized dogs.
3.2. Effect on blood pressure of animals: the decoction of hyssop has a transient hypotensive effect on anesthetized cats and dogs, etc. The decrease of blood pressure is accompanied by respiratory excitation, and the hypotensive effect is not quickly tolerated, and it is speculated that its mechanism of action may be related to the release of histamine, cardiac inhibition and expansion of peripheral blood vessels.
4. The role of the intestinal tube
Selected rabbits, both male and female, respectively, selected duodenum, jejunum and ileum, each section 3-4cm, according to the smooth muscle routine experimental method. With 16 rabbits, 56 segments of intestinal tubes, given alcohol extract, can make the above intestinal segments excitation, tension increases, contraction force is strengthened, and can be quickly recovered after changing the liquid.
5. Action on uterus
5.1. Action on smooth muscle of isolated rat uterus:
Randomly selected virgin rats (without sex cycle smear examination) 28, body got 230±SDI7.3g, according to the conventional method of preparing isolated uterus specimens, uterine muscle segments of 1.5cm in length, placed in a constant temperature Loh tank containing DeJaoln's solution I ( 20 ml), adjust the baseline tension of 1.5 g, and equilibrate continuously with 95% O2+5% CO2 (32±0.5°C, pH=7.4-7.6) for 30-60 minutes, then start the experiment. During the experiment, the myodynamic transducer was connected and the uterine contractile activity was traced by a desktop automatic equilibrium recorder. The area under the uterine contraction curve (UCA) was calculated by an electrometer as an index. The effects of four different doses of total saponins of hyssop on the uterus of non-pregnant isolated rats were observed. The total saponin of hyssop had a significant excitatory effect on the uterine smooth muscle of rats. The amplitude of uterine contraction increased, the frequency accelerated and the tension increased after the administration of the drug. The contractions were mainly regular rhythmic contractions, and spasmodic contractions rarely occurred.UCA increased significantly compared with that before the administration of the drug (P<0.001). From the UCA within 10 minutes after administration, there was a corresponding increase in UCA with increasing dose. The peak of UCA was also gradually shifted forward in all groups, and the latency of uterine contraction was shortened accordingly. Ten specimens were randomly selected from each dose group of the above experiments, and the drug was administered once, and after 3 minutes of action, the fluid was changed and rinsed three times, and then the drug was administered once after the specimens recovered to observe the effect of repeated administration on the uterine smooth muscle. The results showed that with the increase of the administered dose, the excitation of uterine smooth muscle by total saponins of hyssop was significantly weakened when repeated administration was performed, and when the dose was increased to more than 0.5mg/ml, the re-administration of the drug did not cause obvious uterine smooth muscle excitation.
5.2. The effects of the drug on the uterus under different physiological conditions:
Twenty-eight female rats were used, of which four were juvenile rats (age of 7 weeks or less), weighing 104±SD2.8g, and the rest were mature nonpregnant or B-pregnant rats, weighing 226.8±SD15.5g.
The nonpregnant mature rats were subjected to a vaginal smear prior to the experiment, and the sexual cycle was determined by TurnerCD's method of dividing sexual cycles. Turner's CD's method of sexual cycle classification, and selected rats in the motile and intermotile stages. Pregnant rats were categorized into three pregnancy states according to gestation period: early pregnancy within 7 days, middle pregnancy from 8 to 14 days, and late pregnancy from 15 days or more. Another 4 rats were taken and continuously injected daily subcutaneously with ? Hexenoestrol 0.lmg/kg *** for 2 days to create an artificial estrus period for experimentation. The experimental method was the same as before, and 8-10 specimens were used in each group of experiments to compare the effect of 0.5mg/ml total glucoside on uterine smooth muscle in different physiological states. The results are shown in Table 5. UCA in the pregnant group was significantly higher than that in the non-pregnant group in the first 10 minutes of drug administration (P<0.05). UCA increased in all groups after administration, and the increases were in the following order of magnitude: late pregnancy group>early pregnancy group>interoestrus group>intermediate pregnancy group, hexenoestradiol group, estrus group
>young age group. The young age group was the lowest and the late pregnancy group was the highest.
5.3. Comparison of the effects of total saponins of hyssop on the cervix and uterine horn of non-pregnant rats: experiment **** with 12 specimens each of the cervix and uterine horn of the non-pregnant rats, the length of the specimens was 1-1.5cm, and the experiment was carried out in accordance with the above method. The total saponin of hyssop 4.5mg/ml was given to compare the effects of the drugs on the cervix and uterine horn, and the results are shown in Table 6.The total saponin of hyssop 0.5mg/ml had no obvious excitatory effect on the cervix of rats. The cervix of rats had no obvious changes in contraction amplitude and frequency after the administration of the drug, except for some increase in tension, while the uterine horn of rats had obvious effects on the cervix of rats, resulting in an increase in tension, contraction amplitude, and accelerated frequency.
5.4. The role of the in vivo uterus in rabbits: 3 rabbits each weighing 2-2.51g of non-pregnant and mid-pregnant (gestation period of 10-20 days) were selected, and were operated under the anesthesia of sodium pentobarbital 25mg/kg i.v. The uterine contraction was recorded with the method of in situ uterine drape. The lower end of the uterine trocar was tied securely to the abdominal wall incision, and the uterus was immersed in low-calcium leucovorin solution (1/4 the normal amount of calcium) warmed to 38°C. A resting load of 3-5 g was applied and after 30-60 minutes of stabilization, the experiment was started when the traced uterine activity was constant. Local administration was used, i.e., the fluid in the cannula was aspirated and then 0.5 mg/ml of total saponins of bovine hyssop (prepared in low-calcium lecithin) was added, and the observation was recorded for 30 min. After the first administration of the drug in 4 animals (half of non-pregnant and half of intermediate pregnancies), the fluid was changed and rinsed for a few times, and the administration was repeated once more.
The results showed that strong contractions could be seen in the in vivo uterus of both non-pregnant and middle-pregnant rabbits within 1-4 minutes after the administration of the drug. The contractions were characterized by increased tension, contraction amplitude and frequency, and the excitatory effect generally lasted for about 25 minutes and gradually weakened. Repeated administration of the drug is still poor excitatory effect, but compared with the first administration, the effect is weakened. Zhu and others analyzed the mechanism of excitatory effect of ABS on rat isolated uterus by taking rat uterine contraction area (UCA) as an index and using anti-inflammatory pain and chlorpromazine as a blocking agent. The experimental results showed that the excitatory effect of ABS on the isolated uterus of rats was significantly attenuated by using anti-inflammatory pain (75mg/only by gavage or by adding anti-inflammatory pain 20ug/ml in the bath) before the experiment. Prostaglandin E2200mg/ml significantly enhanced the excitatory effect of ABS on rat uterus. Chlorpromazine 0.5mg/ml also significantly attenuated the excitatory effect of ABS on the uterus of pregnant and non-pregnant rats, while atropine 10ug/ml had no significant effect on the excitatory effect of ABS on the uterus of rats. It is suggested that ABS has no significant effect on the excitation of rat uterus. It is suggested that ABS excitation of rat uterus may be related to the promotion of prostaglandin and 5-HT release.
6. Anti-fertility effects
6.1. Total saponins (ABS) on the rat anti-fertility and abortion:
Select 36 female virgin rats weighing 200-250g and 18 mature males weighing 250g or more, and keep them in the same cage for more than 2 weeks, and according to the literature method, randomly divide the female rats into 3 groups (12 rats in each group). The female rats were randomly divided into 3 groups (12 rats in each group) for the experiment. The female rats were executed after stopping the drug, and the uterus was dissected to calculate the percentage of pregnancy, the average number of live fetuses, no fetuses and the number of points of implantation in each group. There was no significant difference in the indicators between the administered group and the control group. The abortion test was performed by taking healthy female rats (230-260g) and male rats (>750g) and mating them in 2:1 cages. The pregnant rats in gestation d10 under ether anesthesia for the Department of abdominal examination, observation of both sides of the uterine horn of the implantation point, suture. dl4-dl9 given ABS aqueous solution, gestation d20 all the animals were executed, Caesarean section, the results of the administration of the group compared with the control group, the rate of loss of the fetus was not significantly affected, only the average body of the fetus was significantly lower than that of the control group (P & lt; 0.01), and did not see the output of the situation.
6.2.Effect of ABS on antifertility and anticonception in mice:
Healthy adult mice were selected, females weighing 26-35g and males weighing 30-45g, and mated in a 2:1 ratio in a combined cage, and then examined for the presence of negative bolus, and the pregnant mice were randomly divided into the administered group and the control group. The drug was administered by gavage once a day on dl-d10, and distilled water was given to the control group. When dl3 of negative bolus appeared, the animals were executed, and the uterus was dissected, and the examination index was the same as that of anti-fertility experiment in rats, and the results showed that S250mg/kg gavage for 10 days presented a certain anti-fertility effect, and the average number of stillbirths, the number of live fetuses and the number of implantation points of this group were significantly different from those of the control group (P<0.05), and the rate of pregnant rats was zero when the dosage was increased by 500mg/kg or more, presenting 100% anti-fertility effects, according to the literature method to find out the effect of anti-fertility. When the dose was increased by 500mg/kg or more, the rate of pregnancy was zero, showing 100% antifertility effect, and the half effective amount of ABS antifertility was 218±48mg/kg according to the literature method (P=0.95). The antifertility test was performed on dl-5 of the negative bolus, and the drug was administered by gavage once a day, and the animals were executed after 6 days of drug withdrawal, and the fetuses were examined by autopsy. The results of the S500mg/kg gavage after the administration of the number of pregnant mice in the group was significantly less than the control group (P & lt; 0.05.
7. Other effects
Promoting ecdysterone to improve liver function, reduce plasma cholesterol effect, the decoction of cowslips or alcoholic extracts of the mild diuretic and shortening of mulberry silkworms age effect.
Ecdysterone in vivo process:
Experiments with 3H an ecdysterone in mice showed that after intraperitoneal injection of l0 minutes, the intensity of radioactivity that is in the organs to reach the highest level, followed by a rapid decline. When administered orally, it was slow, and the amount in the liver, blood, kidneys and other organs was lower than when injected intraperitoneally. Whether administered by gavage or intraperitoneally, the liver was the most active organ. When injected intraperitoneally, the radioactivity appeared rapidly in the feces or urine, but slower when administered orally, and both routes of administration showed more in the feces than in the urine, indicating that the broken-absorbed ecdysterone was mainly excreted through the liver and gallbladder into the intestinal tract.
Pharmacological (toxicological)
Pharmacological (toxicological)
Ecdysterone mice intraperitoneal injection of the LD50 is 6.4g/kg, the hyssop stanolone 7.8g/kg, gavage, both >9g/kg. the above samples of the decoction according to the 60g/kg/day once a day, for 30 days, the animals (mice), blood, renal function, the main viscera, and body weight, activity, and so on and the comparison of normal control group, no abnormalities occurred. Abnormalities.
The root contains triterpenoid saponins: oleanolic acid a-L-hamnopyranosyl-β-D-galactopyranoside (oleanolic acid a-L-hamnopyranosyl-β-D-galac-
topyranoside).
Topyranoside)[1,2]. Another kind of peptide polysaccharide ABAB with immune activity is composed of glucuronic acid (glucose), galactose, galacturonic acid (galactose), arabinose, and rhamnose according to the molar ratio of 12:2:1:1:1, and the content of peptide is 24.7%, which is composed of glycine, glutamicacid, glutamate, glutamic acid, and glutamic acid. The peptide content is 24.7%, mainly composed of glycine, glutamic acid, aspartic acid and serine, with a relative molecular mass of 23,000 [15]. It also contains ecdysterone, inokosterone, rubro-
sterone, and arginine, glycine, serine, aspartic acid, glutamic acid, threonine, proline, and proline. From the Divine Husbandman's Classic of the Materia Medica.
1. TAO Hongjing: Niu Knee, now out of the near road, Cai Zhou is the most good. Big soft and moist, its stem has a section like cow's knee, so it is also named. The cloud has male and female, the male stem purple and large section for the win.
2. "Rihuazi Materia Medica": the cow's knee, Huizhou, long white, near the road, Suzhou, the color purple.
3. "Herbal Tujing": cow's knee, now Jianghuai, Fujian and Guangdong, Guanzhong also have, but not as true as the Huizhou. Spring seedlings, stems two, three feet high, greenish purple, with knots like a crane's knee, but also like a cow's knee, so the name. Leaf tip rounded like a spoon, two two opposite, in the nodes of flowers for spikes, autumn fruit very fine. There are two kinds of this, stem purple nodes large male, green fine for female. The roots are picked in February, August and October and dried in the shade. Roots very large and soft and moist is good. Leaves can also be used alone.
4. "Compendium": hyssop, everywhere, called the soil hyssop, can not be served, but the northern soil and Chuanzhong people planted dill is good. Autumn collection of children, to the spring planting, the seedlings of the square stem storm section, the leaves are opposite, rather like amaranth and long, and pointed SHAO. autumn month of flowering, for the spikes knot, like a small mouse negative insects, astringent hairs, are attached to the stem inverted. At the end of September, take the root, soak in water for two nights, 挼 remove the skin, wrapped and dried, although white straight expensive, but 挼 remove the white juice, into the medicine is not as strong as to leave the skin. The young seedlings can be used as vegetables. According to Chen Rihua "experience formula" cloud: the old man suffered from gonorrhea for a long time, a hundred medicines do not work, and occasionally saw Lin Ting "set of essentials" in the use of hyssop, served and healed. Ye Chaozhi loved ones suffering from gonorrhea, flowing urine in the basin, condensed as a corm of Konjac, a village doctor used hyssop root decoction, drink five services, the name of the medulla oblongata soup, although not immediately healed, and the blood color faded, long time is the old, after ten years of disease again, and then served and then recovered. Because of the examination of the herb, see "after the elbow prescription" treatment of urinary disadvantage, stem in the pain want to die, with hyssop and leaves, boiled in wine to serve, this time and then flicked out, the table of its miraculous work. Also according to Yang Shiying "Direct Finger Formula" cloud: urinary gonorrhea, or blood in the urine, or sandstone distension, with one or two of the Sichuan hyssop, two water, decoction of one, warm service. A woman suffered from this for ten years, served to be effective. Earth hyssop can also. Or into the musk, frankincense is particularly good. 1. Ben Jing: Main cold and damp impotence paralysis, limb contracture, knee pain can not be flexed, expelling blood gas, injury to heat and fire rot, abortion.
2. "Other Records": the treatment of injuries in the less gas, male kidney yin elimination, the elderly loss of drowning, tonic in the continued extinction, fill the bone marrow, in addition to the pain in the brain and lumbar spine pain, the woman's menstrual water can not be, the knot of blood, the benefit of the sperm, yin qi, to stop the hair white.
3. "Treatise on Medicinal Properties": treating impotence, tonifying the kidney and filling in the essence, removing the knot of evil blood flow, and helping the twelve meridians.
4. "Rihuazi Materia Medica": treating lumbar and knee softness, timidity and coldness, breaking the knot of symptoms, draining pus and relieving pain, postpartum pain in the heart and abdomen, and blood transportation, dropping the fetus, and aphrodisiac.
5. "Materia Medica Diffusion": with Cistanchis soaked in wine, beneficial to the kidneys; bamboo and wood thorns into the flesh, mashed fomentation, that is, out.
6. Elemental Zhang: strengthening the tendons.
7. "Supplement to the Diffusion of the Materia Medica": it can lead all kinds of medicines downward.
8. "Yunnan Materia Medica": stopping pain in the tendons and bones, strengthening the tendons and relaxing the tendons, stopping soreness and numbness in the waist and knees, breaking up blood stasis and dropping the fetus, dispersing tuberculosis, attacking scrofula, retreating carbuncles, scabies, blood wind, psoriasis, pus areoles.
9. "Compendium": treatment of prolonged malaria, cold and heat, five drenching urine and blood, pain in the stem, dysentery, paralysis of the throat, mouth sores, toothache, carbuncles, swollen sores, wound folding.
10. "Materia Medica Zheng": the main blood-heat impotence paralysis of the hands and feet, blood dryness and constriction, through the astringent secret of the bladder, the large intestine dry knot, tonifying the medulla oblongata to fill in the essence, benefit yin and activate blood.
11. "Materia Medica Prepara": Steamed in wine, it benefits the liver and kidney, strengthens the tendons and bones, treats lumbar and knee pain, impotence and contracture of muscles, impotence and loss of drowning, malaria for a long time, dysentery, and injuries to the middle of the less qi, and when it is used in raw form, it disperses the bad blood, breaks the knot, treats all kinds of pains in the heart and abdomen, gonorrhea, urination, blood, menstrual closure and difficult to give birth to a baby, paralysis of the throat and toothache, and canker sore.
12. Zhu Zhenhenheng: hyssop, can attract all kinds of drugs downstream, tendon gout in the lower, it is appropriate to add the use of.
13. "Compendium": the master of the disease of the cow's knee, roughly wine can tonify the liver and kidneys, raw can go to the bad blood, the two only. The treatment of bone pain of the waist and knees, impotence of the feet, yin ablation, loss of drowning, prolonged malaria, and injuries of the middle and lesser qi is not based on its ability to tonify the liver and kidneys. It is also used for treating obstruction in the abdomen, pains in the heart and abdomen, carbuncles, swollen sores, gold sores and fractures, pain in the throat and teeth, blood in the urine, and diseases of menstruation and fetus and childbirth, but not for removing bad blood.
14. The Classic of the Materia Medica: Niu Knee is a tonic that can go away and is good at descending, so it enters the liver and kidneys. It is used in treating impotence and paralysis caused by cold and dampness, contracture of the limbs, and pain in the knees. When the liver, spleen and kidneys are deficient, the cold and dampness will become paralysis, and the limbs will be contracted and the knees will not be able to be flexed and stretched. This medicine is walking and downstream, it can expel cold and dampness and remove paralysis will be. Covering the liver is tendon Shu, downstream is the knee, the blood line is pain. By blood gas, Judas cloud can pass the stagnant blood condensation. Detailed medicinal properties, gas as paralysis. Injury to the heat and fire rot, blood scorched disease, blood line and live, pain from stopping. Into the liver line blood, so abortion. Injury in the less gas, the man yin elimination, the old man lost drowning, all the kidney deficiency of the wait also. Brain is the sea of marrow, brain dissatisfaction is empty and pain. Waist is the internal organs of the kidney, spinal cord in the brain, kidney deficiency, less marrow, the waist and spine pain; blood deficiency and heat, hair white. If you are not able to win and labor, you will be injured. Liver blood, kidneys hide the essence, and severely tonifying the liver and kidney, the blood is sufficient and full of essence, the evidence of self convalescence. If the blood is flowing, then the moon water will flow freely, and the blood knot will disperse.
15. "Materia Medica Tongxuan": according to the five lymphatic conditions, extremely difficult to see the effect, but one or two cow's knees, into the frankincense a little decoction, and even into a few doses of peace, the nature of the main downward, and can slip the hole.
16. "Drugs": the knee, sweet taste can be complementary, with astringent astringent convergence, and bitter straight down, used in the kidney. Covering the kidney, astringent astringent blood, lead to all drugs downstream. When used raw, it is used to promote the flow of urine, astringency of tubes, pain in the stem, stagnation of blood, obstruction of obstruction in the abdomen, closure of menstruation in women, and obstruction in the postpartum period, and to activate the flow of blood downward. Wine system cooked is complementary, the main treatment of contracture of the limbs, lumbar, knee and leg pain, bone and tendon pain, malaria, thirst, damp-heat impotence paralysis, old age, loss of drowning, to take the blood nourishing yin function.
17. "Ben Jing Feng Yuan": the knee, although the nature of walking tendons, but slippery products, the essence is not solid, the end is not appropriate. The wine can be steamed to nourish the tendons, raw, then go to the bad blood. Outer Terrace" to cure long-lasting labor malaria, "after the elbow" to cure stroke storm disease, "Yannian" to the next cell, "Health" to the fomentation of fomentation folds, Mei Shi to the pounding of the coating of gold sores, "Qianjin" to the pounding of the poisonous swellings, "set of tests" to the drowning of the closure of all to take the nature of the slippery orifices, eliminating the blood detoxification function. Although strong yin strong tendons, and gas deficiency subsidence, easy to defecate, dreaming spermatorrhea, pregnancy and leakage are prohibited. But the odor and shape of the Sichuan production, and the continuation of the as if, the Yu no essence of the slippery. Cover the kidney Division closed storage, the liver main excretion. This flavor specializing in excretion, but no solid benefit of the function, the world is presumed to benefit the kidneys, and the cultivation of the next element of the drug is often used, and the extended theft into the room how different.
18. "The Classic continued": impotence and paralysis are all inter-fascicular disease, and cold and dampness have been unification, unification of the impregnation of the fascia for the disease, has been smoked burn fascia for the disease. Su Wen discusses paralysis as a disease of immersion and impotence as a disease of smoldering. The treatment of hyssop is wonderful in that it does not have to ask if it has been transformed or not, but it is determined that its disease is pain between the tendons and joints, and those who cannot flex or extend can do so. The main "Bie Lu" continued to increase, are melting the "this scripture" of the purpose and expansion of the person. The strongest of the strong is made soft, the haggard is made moist, the upper is made lower, the broken is made connected, the blocked is made through, and the fire is suppressed to make the water, and the water is helped to make the treatment of the full line.
19. "Medical Zhongzhong Ganshi Lu": knee, the original tonic products, and good to attract the gas and blood downstream, is to use the medicine for its downstream, and always for the introduction of menstruation. Therefore, good treatment of kidney deficiency lumbar pain and leg pain, or knee pain can not flexion and extension, or leg impotence can not be any ground. Also cure women's menstrual occlusion blood wither, promote the birth of the next child. And good treatment of gonorrhea, diuresis, which are good downstream effect. However, "Beilu" also said that it is in addition to the pain in the brain, Shizhen also said that its treatment of mouth sores and toothache why? Cover these certificates, are due to its gas and blood with the rise of fire and heat caused by the reuse of hyssop to lead its gas and blood downward, and can lead its floating over the fire downward, so it can be healed. I realized this reasoning, used to treat cerebral hemorrhagic evidence, with ochre, dragon bone, oyster heavy fall astringent products, no hand effect, the cure is not more than a few years. The nature of the special injection, where the lower jiao gasification is not solid, all the slippery evidence are contraindicated.
20. "Justice of the Materia Medica": the cow's knee, sparing drainage, the Lord are all the congestion of the disease, the "Classic" said the main cold and dampness, when quoted from the "Imperial Review" as typhoid. Its treatment of wet flow joints of impotence paralysis, contracture of the limbs, knee pain can not be flexed and extended, solid dredge congestion of the specialties, to be non-exhaustion of blood and qi of the detention of the attempt, can be argued. However, all impotence paralysis, there are two layers of dampness obstruction and blood failure. Damp obstruction, but in the drive and make the circulation, blood failure, must also be nourished to help its operation. Knee bends and can reach, no matter what, the evil, certainly rely on the king, to raise the positive, but also rely on the auxiliary, so impotence and weak paralysis, bone pain and tendon contracture of all the evidence, can not be a day without this. By the blood gas, that is, so through its congestion, the treatment of injuries hot fire rot, but also to help its circulation, and that is, we can know the nature of the knee, favoring the cold. Therefore, the main heat injury fire injury. Cold and wet for the disease, it must not be its own, the error of the above, it is more obvious. Those who can abort the fetus, slippery downward force also. "Beilu" treatment of injuries in the less gas, but also to the damp heat congestion, the gas does not declare the words, not the right gas is not full, Qing Yang subsidence of the appropriate. Its main man yin elimination, but also the main heat injury yin, non-compensatory liver and kidney of the real yin also. The old man lost drowning, cover the ground channel is not accessible, and for the illness of retention of urine, must not be the lower element is not solid, urine drowning bed of the waiting. The so-called tonic in the continued absolute fill the bone marrow, beneficial essence, the yin qi said, are both congestion and sparse, the positive gas since the prosperous, can not be mistaken for the cow's knees to fill the product. Brain pain, more than the rise of Yang evil, hyssop under the act of smooth, then the gas fire from the submerged. Lumbar spinal pain, but also the congestion of the meridian tunnel, hyssop declared through the veins, then the joints since the benefit. And the main menstrual fluid, blood knot and other evidence. The true meaning of solid breaking stasis and stagnation guide, all of which should be on the dredging layer of thought, then the real function of the cow's knee is clear. Selection. Ox Knee Soup ("Thousand Golden Essentials"), used to treat the birth of the child's cytosol does not come out, so that the cell rot. 2. Zhen Liver Wind Extinguishing Soup ("Medical Zhong Zhi Zhen Xi Lu"), the main treatment of the liver wind within the movement of the liver, liver yang on the hyperactivity of the pulse long and forceful, or on the fullness of the lower part of the virtual, head and eyes are often dizziness, or the brain is often for the heat, or the eye distension, tinnitus, or heart fever, or yelping, or limbs are gradually feel unfavorable, or the mouth and eyes are crooked, or the face of the face as drunkenness, or dizziness to the upside down, fainting not know people, move time to be the first time to the upside-down, and the time to be the only time to the side. The formula is used for treating swollen feet, mental distress, and menstrual failure.4 The formula is used for treating not much evil dew after delivery ("Secret Essentials of Wai Tai").5 The formula is used for treating Crane's Knee Wind ("Materia Medica").6 The formula is used for treating fetal clothes not coming out ("Meishi Jiejian Fang").7 The formula is used for treating rheumatism and paralysis ("Taiping Shenghui Fang"). 8 The formula of San Miao Wan ("San Miao Pill") is used for treating the pains and symptoms in the body of a patient with a fever, or a fever in the heart, or frequent yelps, or the limbs gradually feel unfavorable, or the mouth and eyes are distorted, or the face looks like drunkenness, or dizziness to the extent of being upside-down, or the faintness of not knowing the person who is moving to awaken and not being able to recover after awakening. 8. Sanmiao Pill ("Medical Zhengzhuan"), for the treatment of damp-heat injection, numbness of the feet, or as the heat of the fire branding. 9. Ox Knee Wine ("Compendium of Materia Medica"), for the treatment of impotence and paralysis, replenishment of the deficiency loss, strengthen the muscles and bones, and in addition to the long-standing malaria. 10. The treatment of urinary pain in the stem ("Elbow After the Square"), for the treatment of adverse urinary pain, pain in the stem, and the treatment of the women's blood knot abdominal pain. 11. Wan Disease Pill ("Three Causes of the formula"), for the treatment of the chamber girl's menstruation is blocked, firm knots under the umbilical cord, large as a cup of liter, and the pain in the abdomen is very strong. 12. Wan Diao Wan ("After Elbow Formula"), used for treating women who cannot get menstruation, have knots under the umbilicus as big as a cup liter, have fever, dysentery and lose weight, which is the obstruction of blood in the abdomen. 12. After Elbow Formula), with the treatment of mouth and tongue sores, rotten.17. Treatment of skin disease formula (Qian Jin Fang), with the treatment of wind-itch hidden rash, bone jaundice, mange, etc.18. Treatment of gold sore pain formula (Mei Shi Jie Qiang Fang).19. Treatment of consumption and malaria formula (Qian Jin Fang).20. Treatment of dysentery formula (After Elbow Formula), with the treatment of dysentery first red and then white.