1. Formula and source
The prescription of Guizhi Fuling Capsule comes from Guizhi Fuling Pill in Zhang Zhongjing's Synopsis of the Golden Chamber in Han Dynasty, which consists of Guizhi, Poria, Paeonia lactiflora, Ji Fang, Poria, Panxie, Clematis, Psoralea corylifolia, Astragalus, Motherwort and Glycyrrhiza.
2. Square solution
2. 1. Live in harmony
Monarch drugs: cassia twig and poria cocos.
Guizhi: sweet and warm, promoting blood circulation and dispelling cold, removing blood stasis.
Poria cocos: diuretic, dampness-removing, spleen-invigorating, qi-invigorating, calming the heart and calming the nerves.
Minister medicine and adjuvant medicine: Radix Paeoniae Alba, Cortex Moutan and Semen Persicae.
Peony and peony: cooling blood and dispersing stagnation, regulating qi and relieving pain.
Peach kernel: breaking blood, removing blood stasis and promoting regeneration.
Guizhi is sweet in taste and warm in nature. It enters the heart, lungs and bladder meridians, and can activate the heart yang, warm the bladder and disperse blood stasis.
Poria cocos is sweet and light, enters the heart, spleen and bladder meridian, and can strengthen the spleen and nourish the heart, eliminate phlegm and promote diuresis.
Paeonia lactiflora is sour in the liver, which can relieve pain urgently, nourish just the dirty, give consideration to the source of metaplasia, promote blood circulation and remove blood stasis.
Peony bark and peach kernel taste bitter and cold, promote blood circulation and remove blood stasis, eliminate symptoms and dissipate stagnation, and clear away blood stasis and heat.
Five drugs * * * have the functions of activating yang, promoting blood circulation, removing blood stasis and eliminating symptoms, which are characterized by eliminating pathogenic factors, removing blood stasis without damaging the healthy, promoting blood circulation without damaging yin, giving consideration to yin and yang, and regulating qi and blood in multiple systems and ranges, but the emphasis is on promoting blood circulation and removing blood stasis to slow down the disease. Is a small sustained-release preparation for treating blood stasis syndrome. Therefore, on the one hand, it can be taken for a long time according to the course of treatment, on the other hand, it can be widely used to treat blood stasis.
2.2. Composition characteristics
Combination of cold and warm: Guizhi warms meridians to dispel cold; Peony bark and peach kernel cool blood, remove blood stasis and clear heat;
Taking both evil and positive factors into consideration: Guizhi warms meridians and promotes yang; Poria cocos strengthens the spleen and benefits qi; Peony softens liver and nourishes yin.
Guizhi dispels cold; Poria cocos promotes diuresis and permeates dampness; Radix Paeoniae Alba promotes blood circulation and dissipates stagnation; Peony bark and peach kernel remove blood stasis and promote regeneration;
* * * Removing blood stasis: Mudan bark and peach kernel remove blood stasis and generate new life; Ramulus Cinnamomi, Poria and Radix Paeoniae Alba can dispel cold and heat, qi stagnation, water and dampness and other pathological factors to remove blood stasis.
Sustained-release block: this prescription is a small-dose sustained-release agent for treating blood stasis syndrome, which can be widely used in blood stasis syndrome, especially for chronic illness, lack of positive energy and excess negative energy.
Second, indications
Guizhi Fuling Capsule is mainly used to treat blood stasis syndrome, especially gynecological blood stasis syndrome. The pathogenesis is retention of blood stasis, qi stagnation blocking collaterals, which will form syndrome block over time. Main indications:
1, lump, lump or nodule, tenderness, refusal to press;
2, pain, tingling, pain has a fixed place;
3. Female menstrual flow is excessive or leaking, with black blood and blood clots;
4, the tongue is dark with ecchymosis, and the pulse is astringent or thin;
5. The hemorheology is in a state of "blood stasis".
Third, the pharmacological effects of each prescription of Guizhi Fuling Capsule
1. pharmacological effects of cassia twig
Active ingredients: cinnamon oil, cinnamaldehyde, etc.
Function: relieve smooth muscle spasm; Antibacterial and antiviral; Diuretics; be antianaphylaxis
2. Pharmacological effects of Poria cocos
Active ingredients: Poria cocos triterpenes, etc.
Diuretics; Antibacterial; Anti-tumor; Calm down; Promote milk secretion; improve immunity
3. Pharmacological effects of Radix Paeoniae Alba
Active ingredients: paeoniflorin, etc.
Relieve smooth muscle spasm; Antiinflammatory; Calm; calm
4. Pharmacological effects of Cortex Moutan
Active ingredients: paeonol, etc.
Antibacterial effect; Calm down and reduce fever; Lowering blood pressure; Reduce capillary permeability and inhibit platelet aggregation; Antihistamines.
5. Pharmacological effects of peach kernel
Active ingredients: amygdalin, etc.
Inhibit blood coagulation and thrombosis; Antiinflammatory; Promote postpartum uterine contraction and stop bleeding; Analgesia; Resist tumor
Fourth, the pharmacological effects of Guizhi Fuling Capsule
1. Improve hemorheological indexes;
2. Inhibit platelet aggregation, increase fibrinolytic enzyme activity and accelerate thrombolysis.
3. Improve microcirculation.
4. Bacteriostasis and sterilization
5. Anti-inflammatory effect, which can obviously inhibit acute, chronic or autoimmune inflammation, and inhibit granulation tissue and adhesion formation.
6. Two-way regulation of uterine smooth muscle: antagonizing spasm and promoting uterine involution.
7. Adjust immunity, enhance cellular immune function, and inhibit autoimmunity.
8. Analgesia and sedation can increase β -endorphin and decrease E2 and F2a of prostate.
9. Anti-tumor effect
10. Regulating endocrine function
Verb (abbreviation of verb) indicates
In modern medicine, Guizhi Fuling capsule is widely used in gynecology, obstetrics, family planning, breast and urology.
Gynecology: hysteromyoma (especially small intramural myoma), chronic pelvic inflammatory mass, dysfunctional uterine bleeding caused by irregular endometrial exfoliation, ovarian cyst, dysmenorrhea, endometriosis, etc.
Obstetrics: postpartum lochia, postpartum urinary retention, ectopic pregnancy, habitual abortion, etc.
Family planning department: bleeding after induced abortion, abdominal pain after IUD release.
Mammary department: lobular hyperplasia of breast.
Urology: benign prostatic hyperplasia, chronic prostatitis.