Valerian contains 0.5 to 2% volatile oil. Its ingredients are diverse and vary with climate and ecological environment. It contains monoterpenes, mainly borneol and its acetate and isovalerate esters. Its sesquiterpene components such as valerenic acid, valeranone, valerenol alkyd, valerenal, etc. have attracted the attention of many people because of their biological activities. Its main skeleton structure They are valerenic acid, valerone and broadleaf valerian glycol (kessyl glycol). Among them, the valerenic acid and broad-leaf valerian ring structures are unique to Valerian plants. Other volatile oil components include: l camphene, α pinene, l limonene, α fenchene, myrcene, phellandrene, l Caryophyllene, γ terpinene, terpinolene, eremophilene, γ selinβ bisabolene, α curcumene, ledol, β-valerine, chatinine, valerian alkaloid A, valerian alkaloid B, kiwifruit [(S)-(—)- actinidine], valerianine and other alkaloids and furofuranolignans (such as 1-hydroxypinoresinol). The water extract of valerian also contains some free amino acids, such as γ-aminobutyric acid ( GABA), tyrosine, arginine, glutamine. In addition, it also contains caffeic acid, chlorogenic acid, tannins, sitosterol, etc. β-D-glucoside (apigenin-7-O-β-D-glucoside), apigenin (apigenin), luteolin (luteolin), diosmetin (diosmetin) and acytin (acacetin); organic acid caffeic acid (caffeic acid), chlorogenic acid (chlorogenic), p-hydroxybenzoic acid. Eleven components including α-curcumene, δ-elemene, β-aperine, and α-farnesene were identified from its volatile oil [2]. There are 23 ingredients including α-bergamotene, δ-junipene, β-bisabolene, trans-β-farnesene, valerenone, chlorophyllol, and β-bisabolol. 16 of them have the same components as the volatile oil of valerian, indicating that there is a certain similarity in the volatile oil components between species and varieties [2]. α-curcumene, camphene, isovaleric acid, trans-β-farnesene, β-bisabolene, etc. Compared with the chemical composition of valerian volatile oil, there are 15 identical components. In particular, the content of the main component bornyl acetate is the highest among the two volatile oils, with 31.21% of valerian and 36.07% of valerian [3]. Gamma-aminobutyric acid (GABA) interacts with benzodiazepine sites. At low concentrations, valerian extract increases the affinity of flunitrazepam. However, when the concentration increases, it inhibits the affinity of flunitrazepam. Valerian extract also enhances the release of preload GABA hippocampal radioactivity induced by K+ or verrudine stimulation.
ene), hesperitinic acid, behenic acid, l myrtenol, myrtle acetate, myrtle isovalerate, valerian Grass roots also contain valerine