Dr. Clove is here to answer that question.

In this era where money never sleeps, we often see all kinds of news about sudden death from staying up late. This puts a friend who is used to going to bed late and staying up late into a deep panic, and then, there are a lot of people asking questions on the Dr. Clove App:How harmful is staying up late? What are all the harms?

Today, Dr. Clove will talk to you about the dangers of staying up late.

A, increased risk of death

Sleep deprivation, staying up late is often accompanied by too long working hours and too short rest, more than a decade of research has shown that the risk of death for people with 5 hours or less of sleep is nearly twice as high as that of people who have 6 to 7 hours of sleep. That's the kind of sleep we're talking about when we're talking about continuous sleep from nighttime to the next morning, not the kind that's irregular and broken down.

Two: Increased risk of heart disease and stroke

The risk of heart disease and stroke associated with staying up all night has been recently recognized, with a well-known paper published in 2012 that pooled data on 2 million people in 34 large studies showing a 5 percent increased risk of stroke and a 23 percent increased risk of myocardial infarction in those whose jobs involved night shifts. A 2012 paper summarizing data from 2 million people in 34 large studies showed that people whose jobs involved night shifts had a 5 percent increased risk of stroke and a 23 percent increased risk of heart attack. In Canada, 7% of myocardial infarctions can be attributed to night-shift workers.

Other studies have shown that people who stay up late for long periods of time have higher loads on blood pressure and heart rate regulation, as well as abnormal regulation of vasoconstriction and immune function: on the one hand, there is an increased likelihood of transient ischemia of the heart, and on the other hand, there is also an increased risk of atherosclerosis of the coronary arteries as well as of plaque instability, which can lead to myocardial infarction.

Both of these factors make it easier for 'malignant arrhythmias', which can be fatal, to occur, ultimately leading to sudden cardiac death.

Therefore, staying up late to increase the risk of sudden death makes theoretical sense, is somewhat confirmed in population studies, and should not be taken lightly.

Three, uneasiness and anxiety increase

Many people stay up late and not at peace, they are often accompanied by a lot of stress and anxiety.

For example, a certain deadline for work and study is approaching, stay up late to catch up on work. Some people stay up late not at work, but at being distracted all the time by things that can be done or not done, such as online shopping, in order to alleviate the pressure brought by the main thing, to put off the arrival of the pressure, but ultimately it will also be beyond delay, and the need to face up to more anxiety.

To paraphrase a phrase from the psychology of procrastination, "We stay up late in anxiety, and we stay up late in anxiety, and we stay up late in anxiety and fear.

And at the same time, staying up late itself has the potential to cause anxiety and other problems. A study involving 10,000 subjects found that sleep-deprived people were up to five times more likely to experience depression and anxiety.

We've known for a long time that stress and anxiety themselves greatly increase the risk of cardiovascular disease onset and acute attacks, so staying up late and anxiety are a vicious cycle that ultimately leads to actual impairment of physical health.

Four, cancer risk increases

A breast cancer study found that night shift workers will increase the risk of breast cancer by 50 percent, and often jet-lagged people the risk of an increase of up to 70 percent, which may be related to sleep cycle disorders brought about by the immune function of the low. For example, people who stay up late often develop mouth ulcers, which are more prevalent in immunocompromised people.

An important function of the immune system is the immunosurveillance of cancer cells. A normal immune system is able to remove most of the abnormally differentiated cells in a timely manner, but when the immunosurveillance role is weakened, a loophole may appear, increasing the risk of developing tumors.

Five, long-term stay up late to make people stupid

In 2014 a study of more than 3,000 people in a variety of industries who stayed up late on duty for more than a decade of investigation and evaluation. Half of these late-nighters worked shift work more than 50 days out of the year.

The results found a significant decline in memory, reaction time, and overall cognitive ability. Although the problems with their cognitive functioning could be recovered after they stopped working shifts and went into a long-term normal routine, it took at least five years. And their risk of liability accidents on the job was much higher than normal.

Six, make up sleep can not eliminate the harm

Make up sleep after staying up late, in fact, or disrupt the body's normal circadian rhythms, because the body's biological clock is not want to adjust on the adjustment, which has a close relationship with the light and habits.

Circadian light through the visual perception to the body's biological clock - the supraoptic nucleus of the brain, the supraoptic nucleus accordingly adjusted a variety of neurological, endocrine regulation, including the regulation of the pineal gland secretion of melatonin to adjust the body's circadian rhythms.

Staying up late is categorized in sleep medicine as "delayed sleep phase syndrome," a type of sleep cycle disorder that also includes jet lag, irregular sleep, and sleep that is not part of a 24-hour cycle.

Unless you can completely mimic the light variations of day and night, staying up all night is bound to disrupt the biological clock. This is evidenced by the health problems of shift workers (e.g., nurses, security personnel, service industry), who, despite being able to catch up after a night shift, are still at high risk for a variety of cardiovascular and metabolic diseases.

Content reference to Dr. Ding's popular article:

"Be alert to the damage that staying up late can do to your body" by Luxenius 丨heart surgeon

"What time should I go to bed before I'm considered to have stayed up late? By Andrew Xu 丨Dr. Neuroscience at Tsinghua University