Common women of childbearing age, spontaneous remission after menopause. The main symptom of breast nodules is periodic breast pain. At first, it was diffuse swelling pain, and the tenderness was obvious in the upper and middle parts of the breast. The pain increased before menstruation every month, and decreased or disappeared after menstruation. In severe cases, there is persistent pain after menstruation. Sometimes the pain radiates to the axils, shoulders and backs, upper limbs, etc. Patients often report that there is a lump in the breast, but only the thickened mammary glands are touched during clinical examination. A very small number of adolescent patients with simple lobular hyperplasia of breast can heal themselves in about 2 years, and most patients need treatment. Then, experts from Harbin Maria Maternity Hospital said that the early symptoms of breast nodules are mainly manifested in the following two aspects: First, breast pain: common for unilateral or bilateral breast pain or tenderness. The course of the disease ranges from 2 months to several years, and most patients have the characteristics of periodic pain, which occurs or worsens in the pre-menstrual period and decreases or disappears after menstruation. It must be noted that although the periodicity of breast pain is a typical manifestation of this disease, those who lack this feature cannot deny the existence of the disease. Second, breast mass: the early symptoms of breast nodules are often multiple, unilateral or bilateral, and more common in the upper quadrant; And the size and texture often change periodically with menstruation. The mass in premenstrual period increases, and the texture is hard. After menstruation, the mass shrinks, and the texture is tough but not hard. During palpation, palpable masses are nodal in structure, with different sizes, unclear boundaries with surrounding tissues, tenderness, no adhesion with skin and deep tissues, and can be pushed, and axillary lymph nodes are not enlarged.