"Miss Puff" tells the emotional life of fashionable men and women in the bustling city in the form of an independent and interrelated short story in each episode. Miss Puff is a fashionable and sexy white-collar worker who lives alone. She has her own little circle of friends - the innocent girl Xiaoruo, the enchanting beauty Thirteenth Demon and the trendy boy Super Mario. The four people have different attitudes towards life and different concepts of love.