Anti-cancer and anti-mutation

Oleanolic acid has antitumor effect on mouse sarcoma-180. Ligustrum lucidum decoction 12.5, 25g/kg, oleanolic acid 50, 100mg/kg subcutaneous injection have obvious inhibitory effects on the increase of micronucleus rate in bone marrow of mice caused by cyclophosphamide and urethane.

Effects on endocrine system

Studies have shown that there are both estrogen-like substances and androgen-like substances in Ligustrum lucidum. By radioimmunoassay, Ligustrum lucidum contains 428.3 1pg/g of testosterone and 0/39.02 pg/g of estradiol. It is proved that Ligustrum lucidum has both testosterone-like and estradiol-like hormone analogues, that is, the same drug has two-way regulation effect. Traditional Chinese medicines such as Ligustrum lucidum have produced estrogen-like effects on vaginal mucosa of powerless mice. The number of large follicles in rabbit ovaries in the medication group increased significantly, and estrogen increased.

Effect on hematopoietic system

Ligustrum lucidum can promote erythropoiesis. Ligustrum lucidum can promote the growth of CFU-E by diffusion box plasma coagulation method. The ratio of CFU-E/5×l4 was128.61.4 (8), and the ratio of CFU-E/ femur was 62040 5450 (8). The CFU-E in femur was significantly higher than that in NS group, but the CFU-D was significantly reduced. Morphological analysis of bone marrow cells in mice after taking the medicine showed that the percentage of erythroid cells in Ligustrum lucidum group was 47.3 2.99 (6) higher than that in NS group 37.3 2.86 (6), while the percentage of granuloid cells was 37.6 3.96 (6) lower than that in NS group 46.6.26 (6), and the ratio of granulose red changed accordingly.

Protective effect on chromosome damage caused by cyclophosphamide and urethane

The micronucleus test showed that the decoction of Ligustrum lucidum, POL 2.5 g/kg 25.0 g/(kg d) × 6, oleanolic acid ih50mg/kg,100 mg/(kg d) × 7, were effective against cyclophosphamide ip 50 mg/(kg d )× 2 and urethane 500 mg/(kg d).

Anti-HpD photochlorination

Ligustrum lucidum can resist the photooxidation of HpD, and its application in vivo can obviously reduce the skin photosensitive reaction of HpD to mice. Ligustrum lucidum 60mg crude drug /ml can obviously reduce the increase of malondialdehyde content in erythrocytes caused by HpD5ug/ml combined with light 10min, and the inhibition rate is 57.7%, which obviously resists the inhibition of acetylcholinesterase activity in erythrocyte membrane. When the inhibition rate is 49.0%, the inhibition rate is 53.3% in mice. The efficiency of Ligustrum lucidum on 1O2 production was 3.5× 10-4 times lower than that of the control group.

Other functions

Ligustrum lucidum also has cardiovascular system effects such as strengthening the heart, dilating coronary blood vessels and dilating peripheral blood vessels. Diuretic, antitussive, laxative and antibacterial effects. Oleanolic acid has some cardiotonic and diuretic effects; Mannitol has a slow down effect; It also contains a large amount of glucose; These may be related to its strong effect.

Side effects of Ligustrum lucidum

(A) the side effects of Ligustrum lucidum

People with deficiency of spleen and stomach and deficiency of kidney yang are forbidden to take it.

People with spleen and stomach deficiency and diarrhea and yang deficiency should not take it.

"Herbal Classic Shu": When herbs for protecting spleen and stomach and red pepper are used together, there is no fear of abdominal pain and diarrhea. Avoid: people with spleen and stomach deficiency and diarrhea and yang deficiency should avoid taking it. Toxic and side effects: Ligustrum lucidum is very toxic to animals. Rabbits take 75g fresh and ripe fruits once, and there is no poisoning phenomenon. Clinical application of this product may cause dry mouth, dizziness, slight abdominal pain, diarrhea and other adverse reactions, which can disappear automatically after stopping the drug. Ligustrum lucidum has a weak laxative effect because it contains a small amount of fatty oil and mannitol. It has no adverse effect on people with constipation and normal stools, and has no obvious effect on people with thin stools and frequent stools when taking them in regular doses. Large doses may cause intestinal slippage.

(2) The edible taboo of Ligustrum lucidum

Avoid spicy, cold and greasy food.

Patients with cold and fever should not take it.

This product should be taken before meals.

Patients with chronic diseases such as hypertension, heart disease, liver disease and kidney disease should take it under the guidance of a doctor.

Children and pregnant women should take it under the guidance of a doctor.

After taking the medicine for 2 weeks, the symptoms are not relieved, so you should go to the hospital.

Edible method of Ligustrum lucidum

(1) Prescription for the treatment of Ligustrum lucidum

Used for cervical cancer and lung cancer.

To treat lung cancer, Radix Adenophorae 30g, Radix Ophiopogonis15g, Rhizoma Polygonati Odorati 30g, almond 9g, Rhizoma Phragmitis 30g, Radix Codonopsis 30g, Dendrobium 30g, Radix Rehmanniae 2 1 g, Fructus Ligustri Lucidi 2 1 g, pollen 30g, Herba Houttuyniae 30g and Prunellae 2/kl. Three times a day.

Early gray hair

Steamed Ligustrum lucidum with wine 400g, sucrose 664g. Decoct fructus Ligustri Lucidi in water for two time, each time for two hours, mixing that obtained decoction, filtering, and concentrating to obtain fluid extract; Then add the syrup made of sucrose into the fluid extract, mix well, and continue to concentrate to a thick paste, which is about 1000g, that is, Ligustrum lucidum paste, and put it in a porcelain vessel for later use. Every time 15g, three times a day, orally.

Treat hyperlipidemia

A proper amount of Ligustrum lucidum is ground into powder and made into pills with honey (each pill contains 5.3 grams of crude drugs), one pill each time, and one month is a course of treatment. Ligustrum lucidum 1000g, honey 500g. Decoct in water, concentrate, and adding honey to obtain extract. 20g daily, mixed with hot water, three times a day, and one month is a course of treatment. Has the effects of nourishing liver and kidney. It is more suitable for treating hyperlipidemia.

Treat burns

Fresh Ligustrum lucidum leaves 1500g, put in 5000ml water, fry to about 500ml, filter to remove residue, continue to boil and concentrate to 250ml, the medicine juice is dark brown, and fresh preparers do not need sterilization. Disinfect the wound surface before using the medicine. After debridement, when there is little exudation during exudation, apply the medicine juice directly to the wound surface with a brush (brush pen for large burn area). After two or three times, a thin layer of scab film forms on the wound surface. In case of excessive exudation, in order to prevent subcapsular effusion, the wound should be bandaged with gauze bandage 12 to 24 hours before applying the medicinal juice.

Treat lower extremity ulcer

0/5 to 20 slices of fresh Ligustrum lucidum leaves/kloc-,washed, put into an enamel jar, and add appropriate amount of decoction. When in use, the medicine is taken to fumigate and wash the affected part, and then the fried Ligustrum lucidum leaves are applied to the wound (or the cleaned fresh leaves are mashed and applied to the affected part), covered with gauze and fixed with adhesive tape, and changed two or three times a day.

lose hair

Ligustrum lucidum 15g, Radix Rehmanniae Preparata 30g, Radix Polygoni Multiflori Preparata 20g. Decoct.

White hair, alopecia areata, alopecia totalis

Ligustrum lucidum 500g, Jushengzi 250g. Boil the cream. Take 20ml each time with warm water, two or three times a day.

eye trouble

Mash with Ligustrum lucidum leaves, add mirabilite, mix well and stick to the eyes.

The tongue is sore and swollen.

Take Ligustrum lucidum leaves and pound the juice, put it in your mouth and spit it out after one minute.

Leukopenia after chemotherapy and radiotherapy

Ligustrum lucidum 15g, Lycium barbarum 30g, Mulberry 15g and Astragalus membranaceus 20g. Decoct with water.

hyperlipemia

Ligustrum lucidum 30g, cassia twig each burnt 15g. Decoct in water, and take it twice in the morning and evening for 30 days.

(2) How to eat Ligustrum lucidum

Ligustrum lucidum honey drink

Ingredients: Ligustrum lucidum 20g, honey 30g.

Practice: First put Ligustrum lucidum in the pot, add appropriate amount of water, simmer for 30 minutes, remove the residue to get juice, and add honey.

Ligustrum lucidum jujube tea

Raw materials: 60 grams of tea, Ligustrum lucidum 10 gram, dried jujube 10 gram.

Practice:

(1) First, dry the above medicinal materials, and then crush them into granules.

(2) Take a proper amount of granules and put them into a cup, and brew them with clear water for drinking.

Ligustrum lucidum black sesame lean broth

Raw materials: 60 grams of lean pork, 40 grams of Ligustrum lucidum and 30 grams of black sesame.

Practice:

(1) Wash the lean pork first and cut it into small pieces.

(2) Wash Ligustrum lucidum and black sesame seeds.

(3) Put all the ingredients into a pot, add a proper amount of clear water, boil over high fire, simmer for 1 hour, and season to serve.

Efficacy of medicated diet: tonifying kidney, blackening hair, nourishing essence and beautifying face. It is suitable for premature gray hair, rough skin, backache, dizziness, hyperlipidemia and hypertension caused by liver and kidney deficiency.

Stewed pork with Ligustrum lucidum

Raw materials: sea cucumber, lean pork100g each, Schisandra chinensis 6g, Ligustrum lucidum, longan 5g each, 3 Chinese dates, 2 slices of ginger and a proper amount of salt.

Practice: Soak Fructus Schisandrae Chinensis, Fructus Ligustri Lucidi and Fructus Cinnamomi, wash Fructus Jujubae and remove the core; Soak the sea cucumber with warm boiled water and cut it into blocks; Wash lean pork and cut into pieces. Put ginger, pork, sea cucumber, Schisandra chinensis, Ligustrum lucidum, longan pulp and jujube into a pot, add appropriate amount of water, simmer until the meat is cooked and the soup is dry, and season with salt.

Ligustrum lucidum mulberry cake

Raw materials: 200 grams of flour, 300 grams of sugar, 20 grams of Ligustrum lucidum, 30 grams of mulberry and Eclipta prostrata, 0/0 egg/kloc-0, yeast and alkaline water.

Practice: Put Ligustrum lucidum, Mulberry and Eclipta prostrata into a pot and add water to fry for about 20 minutes to get juice and break the eggs. Mix flour, yeast, egg liquid, white sugar and medicinal juice, knead into a ball, add alkaline water after fermentation, knead into a cake, steam in a steamer for about 15 minutes until cooked, and eat as a snack.

Ligustrum lucidum porridge

Raw materials: 5 grams of Ligustrum lucidum, 0/00 grams of japonica rice/kloc.

Practice: Wash Ligustrum lucidum with water and put it into a gauze bag; Wash the japonica rice, put it in a pot, put it in a medicine bag of Ligustrum lucidum, and add water to cook porridge.

Ligustrum lucidum wine

Ingredients: 200g of Ligustrum lucidum, 500ml of low-alcohol liquor.

Method: when the fruit is ripe in winter, it is harvested, cleaned, steamed, dried, put into low-alcohol liquor, sealed, shaken 1 time every day, and taken after 1 week.

Usage: 1 2 times a day, each time 1 small cup.

Efficacy: tonify liver and kidney, resist aging and remove spots.

Indications: senile lipofuscin spots. Internal heat due to yin deficiency, soreness of waist and knees, dizziness, weakness of limbs, lumbago due to kidney deficiency, premature graying of hair, vexation and insomnia, dry mouth and throat, flushed face, hot hands and feet, red tongue and thready and rapid pulse.

P.S.: Quoted from Compendium of Materia Medica.

Effect of soaking Ligustrum lucidum in water to drink

Ligustrum lucidum is beneficial to liver and kidney; Clearing deficiency and heat; Clear your eyes. Indications: dizziness; Waist and knees are sore; Nocturnal emission; Tinnitus; Hair becomes gray early, and bone steaming hot flashes; Dark eyes and other effects. Therefore, making tea will have the above effects.

In addition, soaking Ligustrum lucidum in water can play a role in lowering blood pressure, and it can have a good effect on hypertension and blood lipid in the elderly. At the same time, it can also be used for the purpose of yin deficiency of liver and kidney. Therefore, soaking it in water, taking it persistently, floating up due to deficiency of fire, sore throat and discomfort due to stagnation of qi and phlegm, and foreign body sensation in the throat are beneficial.

Er zi ju Hua yin

Ligustrum lucidum, Lycium barbarum each 15g, Chrysanthemum morifolium 10g. Decoct water and drink.

This prescription uses Ligustrum lucidum and Lycium barbarum to nourish liver and kidney and improve eyesight, and chrysanthemum to nourish liver and improve eyesight. It can be used for treating yin deficiency of liver and kidney, dry eyes, blurred vision, or vision loss.

Two-green Ligustrum lucidum tea

Green sepal plum, green tea, orange complex each 3g, Ligustrum lucidum 6g. Mash Fructus Ligustri Lucidi, put it into a cup with the first three ingredients, and brew with boiling water. Daily 1 dose, take it at any time. Functions: nourishing yin, relieving sore throat, promoting qi circulation and resolving phlegm. It is good for sore throat, foreign body sensation in throat, and drinking it due to yin deficiency of liver and kidney, floating of deficiency fire, stagnation of qi and phlegm.

The difference between Ligustrum lucidum and Brucea javanica

Among the Chinese herbal pieces of fruits, Ligustrum lucidum and Brucea javanica are similar in size and color, so we should pay attention to the differences in formula operation to avoid confusion.

glossy privet

Ligustrum lucidum is a dried and mature fruit of Ligustrum lucidum belonging to Oleaceae. It is processed and used as medicine. It is oval, oval or kidney-shaped. Its surface is dark blue to black, and it is mostly shriveled. Its peel is fragile, its inner core is hard, brown and black, with longitudinal edges. After being broken, the seeds are usually 1 grain, black and kidney-shaped, and shriveled. Sweet and slightly bitter. Ligustrum lucidum has the functions of nourishing liver and kidney, improving eyesight and blackening hair. It can be used for dizziness, tinnitus, soreness of waist and knees, premature graying of hair and beard, and blurred vision.

Java brucea

Brucea javanica is the dried and mature fruit of Brucea javanica, a plant in the family Bitter, with oval shape, black or brown surface, raised reticular wrinkles, irregular polygonal mesh and obvious ridges on both sides. The top is tapered, and the base has concave stipe marks. The shell is hard and brittle, the seed is oval, the kernel is milky white, oily and bitter. Brucea javanica has the functions of clearing away heat and toxic materials, arresting malaria, stopping dysentery and corroding wart, and can be used for dysentery and malaria. External treatment of wart, corns. Brucea javanica has little poison, which is forbidden for pregnant women and children.

Key points of difference between the two.

The pericarp of Ligustrum lucidum is shriveled; Brucea javanica fruit leather reticular wrinkles.

The seed kernel of Ligustrum lucidum is brown-black, not oily and slightly bitter; Brucea javanica seed kernel is milky white, oily and bitter.

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