1, the time standard of depression, depression must last for at least two consecutive weeks before it can be called depression.

2, exclusion criteria, patients in the past life did not meet the criteria of hypomania or mania, nor was it caused by psychoactive substances or organic mental disorders.

3. The patient's core symptoms and additional symptoms should be combined. The core symptoms include depression, loss of interest or fatigue. Additional symptoms include inferiority, self-blame, repeated thoughts of wanting to die or commit suicide, and decreased thinking or attention ability. Agitation means losing your temper, getting angry easily, and getting bigger in mood and temper.

4, any type of sleep disorders, appetite changes, some appetite changes are reduced, some are increased, and the weight will change accordingly.