Health function
Anthocyanins in blueberries can delay memory loss and prevent heart disease, so they are regarded as super fruits. According to the US Daily Health News, recent research has added a reputation to super fruit, and eating more blueberries or drinking anthocyanin drinks can help prevent colon cancer. Studies have found that blueberries can play this role, because blueberries and other fruits contain a natural compound called pterostilbene, which helps to prevent damage to the body in the early stage of cancer. Pterostilbene is an antioxidant and anti-inflammatory agent, which exists in blueberries and blackberries. Ohio University found that animals that eat rough berries have a lower risk of colon cancer by 80% and digestive tract tumors by 60%. German researchers have found that drinking 2-3 cups of apple juice a day can also prevent colon cancer. However, people should not rely on any kind of food to prevent colon blueberry cancer. They must have a balanced diet and supplement fruits and vegetables rich in antioxidants in many ways. Blueberries contain a lot of purple components, which are anthocyanins. It can eliminate eye fatigue, keep your eyes working and make you have charming eyes. Blueberries can improve eyesight and eliminate eye fatigue: Blueberries VS Vitamin A: Vitamin A can also protect eyes. What is the difference between blueberries and blueberries? VA is only one of the basic nutrition of retina in speech, and blueberry not only contains vitamin A, but also mainly contains anthocyanins, which can directly accelerate the synthesis and regeneration of retina and rhodopsin, and make eyes shine. -On July 22nd, 2008, Health Times published an article by Kazuhiro Nakagawa, a Japanese biomedical doctor: Medical clinical reports show that anthocyanins in blueberries can promote the regeneration of rhodopsin in retinal cells, prevent myopia and improve vision. Professor Walker, a doctoral supervisor at the University of Toronto and a doctor of medicine at Harvard University, confirmed that blueberries can prevent myopia and various eye diseases. -"Blueberries Give You Good Eyes" Author: Kazuhiro Nakagawa
Blueberry (Vaccinium uliginosum) belongs to Vaccinium of Ericaceae. The fruit is blue, covered with a layer of white fruit powder, with delicate pulp, sweet and sour fruit flavor, unique flavor and rich nutrition. Blueberry is a wild deciduous shrub belonging to Vaccinium of Ericaceae, which is called Indigo and Mulberry Mountain in different habitats. Blueberries growing in the virgin forest in the northern Daxing 'anling Mountains of China are called "Dupersimmon". Blueberries can resist the cold of -50℃, their roots grow in frozen soil all the year round, and their fruits are rich in nutrition. Wild blueberry is a precious wild fruit with high nutritional value. According to Tufts University's analysis, among 40 kinds of vegetables and fruits with antioxidant effects, the content of anthocyanins in blueberries ranks first. Among all fruits and vegetables, blueberry has the highest anthocyanin content, and the part with the richest anthocyanin content in blueberry is in its unique purple peel. Blueberries contain special nutrients such as anthocyanins, organic germanium, organic selenium, arbutin, amino acids, fruit acids, etc., which are unmatched by any plant, especially anthocyanins composed of 16 bioflavonoids, which have superior physiological activities than ordinary plant anthocyanins. In recent years, wild berries have attracted more and more attention in food and health care products, which is due to the unique health care function of blueberry anthocyanins. Blueberry fruit is rich in anthocyanins (anthocyanins), which mainly have antibacterial, anti-free radical, anti-vision loss, anti-arteriosclerosis and anti-thrombosis effects. Vaccinium uliginosum juice can be used to extract cranberry pigment, which is widely used in food coloring and health care products for astronauts and primary and secondary school students to prevent vision loss and degradation. According to the research of scientists in the United States, Japan and Europe, regular consumption of blueberry products can obviously enhance vision and eliminate eye fatigue; Nourish the skin; Delaying brain aging; Has therapeutic effect on capillary diseases caused by diabetes; Enhance heart function; Stop Alzheimer's disease. It is precisely because of its nutritional and medicinal functions that the International Food and Agriculture Organization lists blueberries as one of the five health foods for human beings. The health value of blueberry products is gradually recognized by more consumers. Wang Yao Pharmaceutical Co., Ltd., a famous pharmaceutical factory in Kansai, Japan, produces a health food Wang Yao Blueberry Treasure for treating pseudomyopia and relieving visual fatigue; France used blueberry extract 85%, VC 10% and β-carotene 5% to make the medicine "Ditamin" for treating diabetic retinopathy, which has achieved good sales results all over the world. Many domestic biotechnology enterprises and large hospitals imported blueberries from abroad or extracted anthocyanins from rare wild blueberries in Daxinganling, and developed drugs to treat pseudomyopia and relieve visual fatigue. The Food and Agriculture Organization of the United Nations lists blueberry as one of the five healthy foods for human beings, and it is called "golden berry". Prevention, the most influential health magazine in America, called it "magic fruit". Blueberries were selected as "one of the top ten best nutritious foods" by Time magazine.
[Edit this paragraph] What is anthocyanin?
Anthocyanin is a pure natural anti-aging nutritional supplement, which has been proved to be the most effective antioxidant discovered by human beings today. The antioxidant activity of anthocyanin is 50 times higher than that of vitamin E and 200 times higher than that of vitamin C, and its bioavailability to human body is 100%, which can be detected in blood within 20 minutes after taking it. Different from other antioxidants, anthocyanins can directly protect the brain and nervous system through the blood-brain barrier.
[Edit this paragraph] The efficacy of anthocyanins
1, cancer prevention
Cancer is also caused by the destruction of genetic material (DNA) by free radicals. By protecting genetic material, anthocyanins will indirectly protect us from cancer. Although it is long-term, anthocyanins do have indirect protective effects. The free radical scavenging effect of anthocyanins can also prevent cancer cells from spreading smoothly, thus protecting more healthy cells from cancer cells. On the other hand, some cancers form tumors by dissolving tissues and cells, and these cancer cells produce lysosomes and protein. OPC can protect protein from protein. For example, the pathogenesis of breast cancer is like this, so taking OPC will have a good inhibitory effect on the development of breast cancer.
2. 1 antioxidant
International authoritative journals such as toxicology report that free radicals can cause 100 diseases, including various cancers, cardiovascular and cerebrovascular diseases, arteriosclerosis, aging and diabetes. Blueberry contains a large number of physiologically active substances, which is called the "number one antioxidant" in fruits and vegetables. It can protect cells from being damaged by peroxide. It has the functions of preventing dysfunction, improving short-term memory and improving the balance and coordination ability of the elderly. The American Center for Human Nutrition Research found that blueberry is the fruit with the richest anthocyanin content, and its antioxidant capacity ranks first among more than 40 kinds of fruits and vegetables. 1986, Masquerel applied for the patent of free radical scavenger function of anthocyanin in the United States. Anthocyanin, as an antioxidant functional food, officially entered the American market, and its application scope is getting wider and wider. Experimental application has proved that anthocyanins have direct or indirect preventive and therapeutic effects on nearly 100 diseases. Anthocyanin can activate epidemic system, protect serum immunoglobulin from free radicals, activate macrophages and enhance human immunity. In the past, because human beings were often troubled by traditional diseases such as lung disease and infection, the research on antibiotics was once the focus of people's research. Later, due to the improvement of human health awareness, the research on vitamins was listed as the focus of people's research. It can be said that human beings have entered the vitamin era from the era of antibiotics. But now people find that although the research on antibiotics and vitamins has been very in-depth, it can not solve the improvement of modern diseases such as cardiovascular and cerebrovascular diseases, diabetes, cancer and sub-health status, let alone the problems of longevity and anti-aging, and the existence of these problems is related to the harm of free radicals to human body. It is scientifically found that free radicals are related to 100 diseases, including heart disease, arteriosclerosis, phlebitis, arthritis, allergy, Alzheimer's disease, coronary heart disease, cancer, etc. If the harm of free radicals to human body is solved, then human cells can really grow freely, and the length of human life directly depends on people's ability to resist oxidation and free radicals. Improving the ability of anti-oxidation and anti-free radicals will provide more opportunities and possibilities for people to live longer and live to 100 years old. Dr. Masquerel discovered anthocyanin, which is considered as one of the greatest discoveries in the history of health in the 20th century. Professor EricGershiwin, director of the Department of Rheumatology, Allergy and Clinical Immunology at the University of California, Davis, said: "From the increase of these cytokines, it shows that anthocyanins are a powerful substance against intracellular pathogens and parasites." Other studies on animals also support the view that anthocyanins can help improve the body's disease resistance. Researchers have studied cats and found that it can improve the ability of some cells to swallow harmful bacteria. Taking chicken as the object, it was found that the antibody reaction of chicken increased. The effect of anthocyanins on improving immunity has been recognized by the whole medical community. At Tufts University, Dr. James Joseph once presided over a famous animal experiment. After letting the old mice eat blueberries, strawberries, spinach and other fruits and vegetables at the same time, the results showed that the motor nerve function, memory and cognition all got high scores, among which blueberries were the most effective. Blueberries are rich in natural antioxidants (phytochemicals), which can resist oxidative stress, delay the aging of nerve cells and avoid being destroyed by oxides. The more exciting discovery in the study is that some memory and coordination defects caused by aging can be reversed by supplementing blueberry extract rich in natural antioxidants. Blueberry fruit is rich in nutritional and health-care ingredients, which makes blueberry developed and produced all over the world as a nutritional and health-care fruit. According to the research of scientists in the United States, Japan and Europe, regular consumption of blueberry products can obviously enhance vision and eliminate eye fatigue; Nourish the skin; Delaying brain aging; Has therapeutic effect on capillary diseases caused by diabetes; Enhance heart function; Stop Alzheimer's disease.
Step 3 improve your eyesight
Medical clinical reports show that anthocyanins in blueberries can promote the regeneration of rhodopsin in retinal cells, prevent severe myopia and retinal detachment, and improve vision. Anthocyanins can improve vision in dim light; This is helpful for drivers at night, people who stare at the screen for a long time, etc. The reason why anthocyanins are beneficial to the eyes has attracted extensive research by scientists, because during the Second World War, pilots of the Royal Air Force always rationed blueberries before carrying out night bombing missions. Studies have shown that anthocyanins in blueberries can accelerate the regeneration of rhodopsin and improve vision, which is of great help to pilots who often need visual flight and have strict vision requirements. After the war, people's research on blueberries expanded to protect blood vessels and other fields. Anthocyanins rich in blueberry ripe berries are widely used in many situations, including scurvy, urinary tract infection, kidney calculi's disease, atherosclerosis, cataract, macular degeneration, night blindness, retinopathy, varicose veins and vascular diseases in patients with long-term diabetes. First of all, medical scientists have found that most eye problems are caused by the conditions of retina, eyeball bone glue and eyeball pressure. The occurrence of these conditions can be traced back to the problem of blood circulation in the eyes. With the growth of age, metabolism deteriorates, eyes are overused, free radicals in the body are destroyed, blood circulation is not smooth, and microvascular permeability of eyes is abnormal. Therefore, when the eyeball, which belongs to one of the peripheral organs, can't get enough nutrition, the bone glue of the eyeball will decrease, which will further affect the elasticity of the eyeball, make it easy to deform, reduce its elasticity, and lead to abnormal vision. Poor blood circulation will cause abnormal pressure caused by the accumulation of body fluids in the eyeball, which will lead to excessive increase of intraocular pressure, leading to eye pain and acidity, and even more serious eye tissue damage, leading to glaucoma and cataract. Therefore, the unique antioxidant components of anthocyanins in blueberries are used to maintain the integrity of blood vessels, strengthen the elasticity of microvessels, promote blood circulation, and maintain normal eyeball pressure, thus alleviating a wide range of eye problems. Anthocyanin is a powerful antioxidant, which can maintain normal cell connection, stabilize blood vessels, promote microvascular circulation and improve the flow of microvessels and veins. Mature purple-black berries of blueberries contain more than 15 anthocyanins, which can effectively inhibit the enzymes that damage eye cells, which also explains why blueberries are beneficial to eye health. So blueberries are especially suitable for students, drivers and so on.
4, oral skin cosmetics
Anthocyanin is called "oral skin cosmetics" in Europe, which can prevent the early formation of skin wrinkles and is the most effective antioxidant in nature at present. It can not only prevent the early generation of skin wrinkles, but also supplement nutrition and eliminate harmful free radicals in the body. In the pure and pollution-free bilberry extract, 95% of the ingredients are natural substances called anthocyanins. Decades of research have found that anthocyanin has many benefits to human health: anthocyanin is a natural sunscreen that can prevent ultraviolet rays from damaging the skin. Skin belongs to connective tissue, in which collagen and scleral elastin play an important role in the whole structure of skin. Dr. A. H. Arstilla of Finland found in experiments that sunlight can kill 50% of human skin cells. But if it is protected by OPC, about 85% skin cells can survive and die. Anthocyanins in anthocyanins can repair injured collagen and elastin fibers. Anthocyanin plays a dual role in skin: on the one hand, it can promote the formation of moderate cross-linking of collagen; On the other hand, as an effective free radical scavenger, it can prevent the abnormal physiological state of "excessive crosslinking" of skin, thus preventing the appearance of skin wrinkles and blisters and keeping the skin soft and smooth. Anthocyanins can also prevent the production of sclerosing protein and inhibit its activity to prevent free radicals or scleral elastase from degrading scleral elastin, thus improving the health of skin from the inside. So as to improve skin elasticity, reduce skin diseases and wrinkles, even eliminate scars and spots, and whiten skin. Therefore, the double protection of anthocyanins from the inside out can prevent the early appearance of skin wrinkles and make the skin smooth and elastic for a long time.
5. Stimulate the synthesis of nitric oxide and improve the quality of male erection.
Nitric oxide is a vasodilator that causes penile erection and plays a decisive role in improving impotence. That is, relaxation factors from epithelium or substances from nerve endings. Substances that can release nitric oxide can promote erection, while nitric oxide synthase inhibitors interfere with erection caused by stimulating cavernous nerve. Nitric oxide synthase is contained in pelvic plexus and penile nerve fibers. Nitric oxide has a stronger antiplatelet effect than prostacyclin, which stays in the blood sinus during erection and can prevent blood coagulation. Therefore, drugs that can release nitric oxide will be important candidates for the treatment of impotence, especially in the case of blood sinus vascular endothelial damage. Anthocyanin, an effective component of blueberry, can stimulate the synthesis of nitric oxide through vascular endothelial cells.
6, remove harmful free radicals in the body
Free radicals are one of the important causes of aging and many diseases. It is estimated that about 80%-90% of aging and degenerative diseases are related to free radicals, including cancer, Alzheimer's disease, Parkinson's disease, skin black spot deposition, cataract, heart disease and so on. Therefore, eliminating harmful free radicals is very important to keep healthy and young. It has been proved that vitamins are oxidized and partially inactivated before reaching the effective parts. Anthocyanin can maintain and enhance the activity of vitamins in human body and is a synergist of vitamins. Blueberry anthocyanins are small molecules, water-soluble substances, oral dosage forms, easy to be absorbed by the human body quickly, and can quickly enter various tissues and organs of the human body after 45 minutes of oral administration. Anthocyanin has good bioavailability in human body, strong affinity to connective tissue, stability in acidic environment, long half-life up to 27 hours and lasting drug effect. The safety of blueberry has been tested and recognized by the authoritative department of the state. According to the experiment, a person weighing about 70 kilograms did not find any adverse reactions even if he took 35,000 milligrams of anthocyanins every day for half a year. The ability of anthocyanin to resist free radicals is 50 times stronger than that of vitamin E and 20 times stronger than that of vitamin C.
7. Improve sleep
With the acceleration of people's pace of life and the increase of work pressure, people's normal biological clock will change from time to time, such as continuous overtime, which makes people's living habits have to be changed, so the problem of insufficient sleep often occurs. People don't get enough rest, which leads to the decline of immune regulation function, endocrine dysfunction and the production of free radicals in the body. It is the decline of human immune function that enhances the activity of free radicals, which can continue to destroy the myelin sheath wrapped in the nerve and harden it, leading to the decrease of the activity level of antioxidant enzyme glutathione peroxidase and causing allergic reactions in the brain. Anthocyanins can penetrate deep into cells to protect cell membranes from free radical oxidation, and have strong antioxidant and antiallergic functions. They can cross the blood-brain barrier, protect the brain from oxidation, stabilize the function of brain tissue and protect the brain from harmful chemicals and toxins. This effect proves that people always say that after taking anthocyanins, their minds are clear and their sleep is completely improved.
8, reduce tissue inflammation
Anthocyanins can reduce tissue inflammation by inhibiting prostaglandin, cytokinin, histidine, lipoxygenase and cyclooxygenase.
9, reduce allergies and allergic reactions
Anthocyanins can reduce the release of histamine, promote the excess histamine to be stored in cells, and inhibit the degranulation of mast cells, thus alleviating symptoms such as allergies, asthma and hay fever. In Europe, if you encounter allergies and other discomfort, most doctors first recommend "anthocyanins".
10, strengthen blood vessels and improve circulation.
Anthocyanin can improve blood circulation, restore lost microvascular function, strengthen fragile blood vessels, and thus make blood vessels more elastic. Procyanidins are called "the antidote to atherosclerosis". For patients with venous insufficiency, proanthocyanidins can effectively relieve the symptoms such as pain, edema and nocturnal spasm, so doctors in Europe usually recommend that patients with varicose veins eat blueberry, a food rich in anthocyanins.
Particularity of blueberry extract
Blueberry extract is the most effective, widely used, with the lowest side effects and the most expensive variety among all plant anthocyanins. In the international market, the price of blueberry extract with anthocyanin content of 25% is 5-6 times that of grape seed extract (OPC content of 95%), which shows the superior function of blueberry extract. The particularity of blueberry extract includes the following aspects:
1, and the bioavailability of anthocyanins is high.
Anthocyanins are composed of different amounts of catechins or epicatechin. The simplest procyanidins are three dimers formed by the combination of catechin and epicatechin, and there are trimers, tetramers and even decamers. According to the degree of polymerization, dimer to tetramer are usually called oligomers (OPC or PCO for short), and more than five oligomers are called polymers (PPC for short). The biochemical and pharmacological activities of procyanidins with different polymerization degrees are different. Anthocyanins in blueberry extracts are oligomers and anthocyanins, which are not only easy to be absorbed, but also can cross the blood/brain barrier to protect cells in various fine tissues, especially the dimers and trimers rich in proanthocyanidins have an inhibition rate of 40% on hydrogen peroxide, showing obvious anti-induction effect.
2. There are many synergistic factors.
Blueberry extract is not only superior in anthocyanin molecules, but also rich in organic germanium, organic selenium, arbutin, amino acids, fruit acids, vitamins and other special nutrients, which are particularly beneficial to human physiology in a free state; If embedded in oligomeric anthocyanins, with the improvement of bioavailability, the effect will be more obvious.
3, high safety
Blueberry extract has been proved to be as safe as ordinary food. The ld50 of blueberry extract for rats and mice is above 4000, and the LD 50 for rats for 6 months is 60 mg/kg d, and for dogs 12 months. It has no side effects and is well tolerated. No teratogenic and mutagenic effects. In terms of reproduction, it is very safe for female animals to take blueberry extract before and after delivery. Blueberry anthocyanin is a small molecule, water-soluble substance, which is easily absorbed by human body. After 45 minutes of oral administration, it can quickly enter various tissues and organs of human body. It has good bioavailability in human body, strong affinity to connective tissue, stability in acidic environment, half-life as long as 27 hours, and lasting drug effect. The safety of blueberry has been tested and recognized by the authoritative department of the state. According to the experiment, a person weighing about 70 kilograms did not find any adverse reactions even if he took 35,000 milligrams of anthocyanins every day for half a year. Hua Ye Bio in Daxinganling is now the world's largest producer of wild blueberry anthocyanins. Blueberry products are based on wild blueberries growing in alpine polar regions and virgin forests above 52 N and at an altitude of1500-2500m in Daxinganling region of China.