In recent years, scientists found that saffron stamens contain saffron acid (Crocitin), saffron (safranal), saffron (Crocin) and saffron bittersweet (Protocrocin) and so on have strong anti-cancer activity. Especially for blood cancer cells, papillary cancer, flat cell tumor and soft tissue sarcoma have strong inhibitory effect. Its anticancer mechanism is to inhibit DNA and RNA synthesis of cancer cells, inhibit the activity of cellular protein kinase and the expression of proto-oncogenes, inhibit the toxicity of benzo(a)pyrene and 12-O-14 acylphosphono-13 acetate (TPA) and other carcinogens, and inhibit the formation of tumors at the molecular level. Its LD50 of cancer cells is 0.8~2muM, and its toxicity is far less than that of retinoic acid, therefore, anticancer active substances such as saffronin will become one of the most ideal anticancer drugs in the 21st century.
The unique and miraculous effect of saffron is widely used by Chinese and foreign medical circles to prevent and treat cerebral thrombosis, vasculitis, myocardial infarction, blood deficiency, menstrual disorders, post-partum bruises, peripheral pain, bruises, neurasthenia, palpitation and epilepsy and other diseases.
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①Treatment of all kinds of lumps and knots: saffron each serving one, punch soup. Avoid eating oil, meat and salt, and eat light porridge. ("Compendium Gleanings")
② treatment of typhoid fever madness, panic and trance: spreading the law that two points, water, a marigold, soak overnight service. ("Medical Lin Jie Yao")
3 treatment of vomiting blood: saffron a, ashless wine. Flowers into the wine, stewed in the soup out of the juice to take. ("Compendium of Gleanings")
Snow lotus has physiological activity of the active ingredients. Umbelliferolide has obvious antibacterial, antihypertensive sedative, antispasmodic effect; scopolamine has expectorant, anti-inflammatory, analgesic, expectorant and antitumor effect, clinical treatment of asthma acute chronic bronchitis effective rate of 96.6%; apigenin has smooth muscle antispasmodic and anti-gastric ulcer effect; on antelope benzene equipped with an obvious choleretic effect. Particularly interested in the snowdrops contained in the colchicine, the component is a typical representative of cell mitosis, can inhibit the growth of cancer cells, clinical use in the treatment of cancer, especially for breast cancer has a certain effect on skin cancer, leukemia and Hodgkin's disease also has a certain effect. It has specific effects on acute gout attacks, reducing inflammation and rapidly relieving pain within 12-24 hours, and reducing the number of attacks with long-term use. In addition, it also has estrogen-like activity, which can prolong the estrous period and the late estrous period, and shorten the inter-estrous period and the pre-estrous period in rats. However, the toxicity of colchicine is large, can cause nausea, loss of appetite, abdominal distension, and in serious cases, intestinal paralysis and constipation, limb pain and other side effects. As the snowdrops contain good curative effect and toxicity of colchicine, so folk in the use of snowdrops in the main treatment of rheumatoid arthritis and gynecological diseases should not be served more.