Female condyloma acuminatum is mainly found in clitoris, labia majora, perianal region, perineum, vagina and cervix. Most female patients with condyloma acuminatum have symptoms such as pruritus vulvae and increased leucorrhea. Female condyloma acuminatum began as individual pink fluffy papules in the early stage, and then gradually increased, tending to be confused or overlapped with each other. External concavities and convexities are inclined in different shapes, such as granulation and papules. Due to local damp and heat, the stimulation is slow and often increases rapidly, and papillary, cauliflower-like and cockscomb-like lesions of different sizes can be organized, which are fluffy in nature and easy to bleed when touched. Because the secretion seeps into the outside, it is white, dirty or red, and the root of the wart is narrow and often pedicled.

The symptoms of male condyloma acuminatum mainly occur in prepuce frenum, coronary sulcus, prepuce, urethra, penis, anus and scrotum. At the initial stage of the disease, it is reddish or dirty red millet-sized particles, which are soft and slightly pointed at the top, and gradually grow up or increase. The symptoms of condyloma acuminatum can develop into papillary or cystic shape, with a slightly wide or banded base and particles on the surface. Condyloma acuminatum in anus is often swollen, like cauliflower, with wet or bleeding surface, and pus often accumulates between granules, giving off a foul smell, which can lead to secondary infection after scratching. Condyloma acuminatum, located in a dry part with low humidity, often has less damage and is flat wart-like. The symptoms of condyloma acuminatum located in hot and humid areas are often filiform or papilloma-like, which is easy to fuse into large pieces.