When we usually have minor illnesses, we will go to the drugstore to buy some medicine and we will be fine soon. But everyone knows that doing so involves great risks, because clinically, there are many kinds of drugs that can cause drug-induced renal damage. In addition to various western medicines, traditional Chinese medicines that are generally considered to have less toxic and side effects are also listed. 1. Antipyretic and analgesic drugs: various cold medicines, such as metamizole, Keshenshen, Baifuning, Tylenol, Contac, and Motrin; analgesics, such as Fenbid, indomethacin, Biliton, naproxen, and Dai Fen, Voltaren, Yingtaiqing, Sanli Pain, Celebrex, etc., may cause kidney damage. This class of drugs may cause nephrotic syndrome or acute renal failure, which is often related to allergies or the kidneys are in a state of ischemia and hypoxia. 2. Anti-infective drugs Almost all types of anti-infective drugs may cause kidney damage. For example, penicillins may cause glomerular damage, acute allergic interstitial nephritis, and acute tubular necrosis. Cephalosporins are more common in acute allergic interstitial nephritis. Commonly used quinolones, sulfa drugs, erythromycin, lincomycin, vancomycin, tetracycline, anti-tuberculosis drugs (rifampicin, isoniazid), antiviral drugs (acyclovir, arabinoside Cytidine, interferon), and the antifungal drug amphotericin B may cause kidney damage. 3. Chinese herbal medicines Don’t think that Chinese herbal medicines are not poisonous to the kidneys. Xianglongdan Xiegan Pills, Ganlu Disinfectant Pills, Fukefenqing Pills, Fenqingwulin Pills, Paishi Granules, Guanxinsuhe Pills, Erdeaf Pills, Compound Pearl Anchuang Tablets, Danggui Sini Decoction, Xuanzhu Lupus Pills and other preparations contain Indiscriminate use of aristolochic acid can easily lead to toxic kidney damage and aristolochic acid nephropathy. Aristolochic acid nephropathy can manifest as tubulointerstitial disease, acute or chronic renal failure, and even uremia. 4. Antihypertensive drugs. Among the commonly used antihypertensive drugs, diuretics, angiotensin-converting enzyme inhibitors and angiotensin receptor antagonists may cause kidney damage. All three classes of drugs may cause acute allergic interstitial nephritis, and the latter two may also cause it by reducing renal perfusion. Kidney failure. 5. Diuretics Various diuretics may induce allergic interstitial nephritis. Acesulfonamide and triamterene can also form crystals to block the renal tubules, causing hematuria and renal failure. Six chemotherapy drugs: chemotherapy drugs, such as doxorubicin, cisplatin, methotrexate, vincristine, bleomycin, nitrosourea cyclosporine, tacrolimus, sirolimus, etc., all have nephrotoxicity . Such drugs are often used in patients with malignant tumors, transplant patients, etc. After weighing the pros and cons, when they must be used, they should not be eaten due to choking. Clinically, doctors will actively hydrate and alkalize urine, or adjust the dosage according to drug concentration to reduce drug nephrotoxicity.