, netizen advice: my grandfather is cirrhosis patients, the disease has been many years, has not been interrupted by the treatment, the condition is always good and bad, the recent period of time, I found that my grandfather's face black, at first did not pay much attention to, but then obviously feel that my grandfather's face is much darker, this is how it is? Is it the deterioration of the disease please experts to introduce me. With the aggravation of liver cirrhosis, some patients will have the symptom of dark face, which is also called liver disease face, in fact, many family members of patients with liver cirrhosis and even cirrhosis themselves do not know why the face of liver cirrhosis will be dark, liver disease experts pointed out that: general chronic liver disease, such as chronic hepatitis B, cirrhosis and so on, may cause the patient's face to be dark, clinically referred to as this kind of face for the "liver disease face". Clinically, this kind of face is called "liver disease face". Most of the "liver disease face" is due to cirrhosis of the liver for a long time in the state of liver malfunction, liver function can not play a good role, resulting in the patient's liver to the body of estrogen inactivation of obstacles, resulting in the accumulation of estrogen in the blood, and the increase of estrogen will reduce the inhibitory effect on the enzyme tyrosinase, so that tyrosine is converted to melanin, resulting in the increase in the amount of tyrosine. The amount of melanin increases, which leads to the deepening of the patient's skin color, causing cirrhosis patients to have dark face and dark skin color and other clinical manifestations. In addition, according to experts' observation: the darkening of the face of cirrhosis patients may be due to secondary hypoadrenocorticism, the liver can not metabolize the melanocyte stimulating hormone secreted by the anterior pituitary gland, which leads to an increase in melanin secretion, resulting in melanin deposition. Finally, liver disease experts remind: cirrhosis patients with dark face is not necessarily a deterioration of the condition, but also according to the onset of the age, the patient's current liver function and ultrasound and other conditions to carry out a comprehensive judgment, and then take appropriate treatment measures to improve the symptoms of dark face. Zhengzhou Zhongda Liver Disease Hospital adopts liver disease examination equipment to comprehensively examine the patient's condition, then selects suitable therapeutic drugs for the patient and formulates a scientific and standardized treatment plan, so as to enable the patient to achieve the ideal therapeutic effect, thus improving the symptoms of darkening of the face. In addition, our liver disease experts 24 hours online for your service, if you still want to understand the situation, you can click on the online consultation, our online experts will give you the most professional, most detailed answers. I wish you a speedy recovery and a positive life again.