Problem description:

Now I'm looking for some drugs to treat functional dyspepsia. I hope I can tell you. Thank you.

Analysis:

Functional dyspepsia is a common digestive system disease, which is mainly manifested as upper abdominal pain, abdominal distension, early satiety (that is, feeling full when eating less, so that the food intake is obviously reduced), belching, loss of appetite, nausea, vomiting and other symptoms, some of which are mainly one symptom, some of which are a group of symptoms, but there is no obvious abnormality in gastroscopy, upper gastrointestinal radiography, B-ultrasound and various tests, and the illness often lasts for several years. This disease is a functional gastrointestinal disease, and the treatment mainly adopts symptomatic treatment. Commonly used drugs are as follows:

(1) gastric acid secretion inhibitors are generally suitable for patients with abdominal pain as the main symptom. They can choose: (1)H2 receptor antagonists, such as cimetidine, ranitidine and famotidine; (2) Proton pump inhibitors can inhibit gastric acid to a greater extent and for a longer time than H2 receptor antagonists. For example, omeprazole (Losec) 20-40mg per day has obvious curative effect, and lansoprazole and pantoprazole can also be selected.

(2) Stomach-invigorating drugs, which are suitable for patients with abdominal distension, early satiety and belching, can be taken with motilin 10 mg three times a day, or cisapride 5- 10 mg three times a day, before meals15-30min, and the course of treatment is 2. A few people have side effects such as bowel sounds and diarrhea after taking cisapride. After reducing the dosage or using it for a period of time, the side effects can be alleviated or disappeared.

(3) Anti-Helicobacter pylori therapy is suitable for patients with Helicobacter pylori infection. The effective antibiotics are clarithromycin (0.5- 1.0g per day), amoxicillin (0 1.0-2.0g per day), metronidazole (800mg per day), and colloidal bismuth, such as bismuth potassium citrate and sulfur.

(4) antidepressants. Many patients are accompanied by insomnia, anxiety, depression, headache, inattention and other mental symptoms. Mild people can be relieved by psychotherapy. Those with obvious mental symptoms can try tricyclic antidepressants such as amitriptyline or fluoxetine, and it is appropriate to start with a small dose. Insomnia patients can take sedatives appropriately.