2 English reference ecliptae herba [Xiangya Medical Dictionary]
Yerbadetajo herb [Xiangya Medical Dictionary]
Yerbadetajo [Xiangya Medical Dictionary]
Herba Ecliptae (La) [Terminology Committee of Traditional Chinese Medicine. Terminology of Traditional Chinese Medicine (2004)]
Yerbadetajo herb [Terminology Committee of Traditional Chinese Medicine. Terminology of Traditional Chinese Medicine (2004)]
3 Overview of Eclipta prostrata
Eclipta prostrata is the name of traditional Chinese medicine. See New Ginseng in Pieces [1]. It is the dry aerial part of Echinacea prostrata L. [2].
Pharmacopoeia of the People's Republic of China (20 10 edition) records the pharmacopoeia standard of this Chinese medicine.
4 Latin name Herba Ecliptae (La) (Terminology of Traditional Chinese Medicine (2004))
5 English name yerbadetajo herb (Terminology of Traditional Chinese Medicine (2004))
6 Eclipta prostrata alias Eclipta prostrata, black ink grass, wild sunflower, rotten foot grass.
Eclipta prostrata, Mo Dou grass and hemostatic grass [1].
The 7-source Eclipta prostrata L. is the dry aerial part of the intestine of the compositae [2].
Eclipta Prostrata L． is the whole grass [1] of compositae.
8 Origin Eclipta prostrata is mainly produced in Jiangsu, Zhejiang, Jiangxi and Guangdong [1].
9 The original plant is an annual herb, with a height of10 ~ 60 cm, and the whole plant is covered with white coarse hair. The juice that flows out after breaking is blue-black in a few minutes. Stems erect or inclined, green or reddish brown. Leaves alternate, elliptic-lanceolate or linear-lanceolate, 3 ~10 cm long and 0.5 ~ 2.5 cm wide, with whole margin or fine teeth, tapering base, sessile or short stipe. The head is axillary or terminal, with a diameter of 6 ~11mm; Involucral bracts 5 ~ 6, green, oblong; Achenes of tongue-shaped flowers are flat quadrangular, and achenes of tubular flowers are triangular, all of which are dark brown and have tumor-like protrusions. The flowering period is from July to September, and the fruiting period is from September to10.
Born in roadside grass, ditches, wetlands or fields.
Eclipta prostrata is mainly produced in Jiangsu, Zhejiang, Jiangxi, Hubei and Guangdong.
10 harvesting and primary processing, cutting when flowering and drying in the sun.
1 1 Nature and taste Tropism Eclipta prostrata is sweet, sour and cold; Return to kidney and liver meridian. (Pharmacopoeia of the People's Republic of China (20 10 edition))
Eclipta is sweet, sour and cool; Into the liver, kidney meridian [1].
12 Efficacy and indications of Eclipta prostrata has the effects of nourishing liver and kidney, cooling blood and stopping bleeding, and can be used for loosening teeth, premature graying, dizziness, tinnitus, soreness of waist and knees, blood heat due to yin deficiency, hematemesis, hemorrhagia, hematuria, bloody dysentery, metrorrhagia and traumatic hemorrhage.
Eclipta prostrata has the effects of cooling blood, stopping bleeding, tonifying kidney and nourishing yin [1];
Eclipta prostrata is used to treat hematemesis, hemoptysis, epistaxis, hematuria, hematochezia, metrorrhagia, purpura, dizziness due to yin deficiency, tinnitus, lumbago, loose teeth and premature graying: 9-30g [1].
Eclipta prostrata is used to treat carbuncle, swelling and sore, and it is pounded; Wet and itchy skin: decocted and fumigated.
Eclipta prostrata for traumatic hemorrhage: tamping or grinding [1].
13 chemical constituents of Eclipta prostrata contain nicotine, aterthienylmethanol, trithione formaldehyde (AFormy1atentieny1), saponins, tannins, bitterness, isoflavones, and beetles.
The whole herb of Eclipta prostrata contains Ecliptine, saponins, tannins and various thiophene compounds [1]. Such as α-trithiophene [1]. There are nicotine, luteolin 7 glucoside, β-geraniol, etc. [1].
The leaves of Eclipta prostrata contain echinacolactone and so on [1].
14 pharmacological effects of Eclipta prostrata extract has preventive effect on liver injury induced by carbon tetrachloride in guinea pigs [1].
The decoction and tincture of Eclipta prostrata have a strong inhibitory effect on diphtheria, and also have a certain inhibitory effect on Staphylococcus aureus, Streptococcus and Escherichia coli [1].
Eclipta prostrata can resist inflammation, enhance nonspecific immunity and cellular immunity, promote hemostasis, increase coronary flow of isolated guinea pig heart, and resist mutation [1].
15 Pharmacopoeia Standard of Eclipta prostrata 15. 1 Name of Eclipta prostrata
Mohanlian
ECLIPTAE HERBA
15.2 source this product is the dry aboveground part of the intestine of the compositae, e clipta prostrata L. Bloom is harvested and dried.
15.3 characteristics This product is all covered with white fuzz. The stem is cylindrical, with longitudinal edges and a diameter of 2 ~ 5 mm; The surface is greenish brown or dark green. The leaves are opposite, subsessile, shriveled, curled or broken, and the intact ones are long lanceolate after flattening, with the whole margin or shallow teeth and dark green. The head is 2 ~ 6 mm in diameter. Achenes are oval and flat, 2 ~ 3 mm long, brown or light brown. Slight breath, slightly salty taste.
15.4 Identification (1) Take this product, soak it in water, and rub its stems and leaves to show dark green.
(2) Surface view of leaves of this product: Non-glandular hairs are mostly 3 cells, 260 ~ 700μ m long, with slightly enlarged basal cells, longer middle cells, thickened walls, obvious verrucous processes, and short, nearly triangular top cells. Stomatal infinitive, 3 ~ 4 accessory guard cells.
(3) Take 2g of this product powder, add 20ml of 70% methanol, perform ultrasonic treatment for 45min, filter, and take the filtrate as the test solution. In addition, 2g of Eclipta prostrata was taken as the control medicinal material, and the control medicinal material solution was prepared by the same method. Then take an appropriate amount of reference substance of Eclipta prostrata A, add methanol to make a solution containing 0.5mg per 1ml, and according to the test of thin-layer chromatography (Appendix ⅵ b), absorb 10μl of the test solution and the reference material solution and 5μl of the reference material solution, and spot them on the same silica gel G thin-layer plate respectively, and use dichloromethane-ethyl acetate methanol water (30: 40:/) In the chromatogram of the test sample, spots with the same color appear at the positions corresponding to the chromatogram of the reference medicinal materials and the chromatogram of the reference substance.
15.5 inspection 15.5. 1 moisture shall not exceed 13.0% (appendix IX H, first method).
15.5.2 the total ash content shall not exceed 14.0% (appendix IX K).
15.5.3 acid-insoluble ash shall not exceed 3.0%? (appendix IX K).
The content of 15.6 was determined by high performance liquid chromatography (Appendix IX D).
15.6. 1 chromatographic conditions and system applicability test with octadecylsilane bonded silica gel as filler; Using methanol as mobile phase A and 0.5% acetic acid solution as mobile phase B, gradient elution was carried out according to the regulations in the following table; The detection wavelength is 235 1nm. The theoretical plate number is not less than 6000 calculated by wedelolactone peak.
Time (minutes): mobile phase A(%), mobile phase B (%) 0 ~1035 → 59 65 → 410 ~ 20 59 4115.6.2 of reference solution
15.6.3 preparation of test solution take the powder of this product (pass through the No.3 sieve) about 1g, weigh it accurately, put it in a conical flask with a stopper, add 50ml of 70% ethanol accurately, weigh it, heat and reflux it 1 h, let it cool, weigh it again, and use 70% ethanol.
15.6.4 determination method respectively accurately suck 20μl of reference solution and test solution, inject them into a liquid chromatograph, and determine to obtain the product.
Calculated by dry product, this product contains wedelolactone (C 16H 12O7) not less than 0.040%.
15.7 Eclipta prostrata pieces 15.7. 1 Processing to remove impurities, slightly washing, cutting into sections and drying.
This product presents irregular segments. The stem is cylindrical, with green-brown or dark green surface, longitudinal edges, white hair, hollow section or white pith. The leaves are mostly shriveled or broken, dark green, with dense white hairs. After flattening, the edges can be seen as whole or shallowly serrated. A flower head. Slight breath, slightly salty taste.
15.7.2 Identification, inspection and content determination are the same as those of the medicinal materials.
15.7.3 Sexual taste and channel tropism are sweet, sour and cold. Return to kidney and liver meridian.
15.7.4 Functions and indications: nourishing liver and kidney, cooling blood and stopping bleeding. It can be used for treating liver and kidney yin deficiency, loose teeth, premature gray hair, dizziness, tinnitus, soreness of waist and knees, blood heat due to yin deficiency, hematemesis, epistaxis, hematuria, bloody dysentery, metrorrhagia, and traumatic hemorrhage.
15.7.5 Usage and dosage 6 ~12g.
15.7.6 Store in a ventilated and dry place.
15.8 Source