1. Carcinogenic and mutagenic effects: Animal experiments or in vitro measurements have found that this product has carcinogenic and mutagenic effects, but this has not been confirmed in humans. 2. If adverse reactions to the central nervous system occur during use, the drug should be discontinued in time. 3. This product can interfere with the test results of alanine aminotransferase, lactate dehydrogenase, triacylglycerol, hexokinase, etc., reducing the measured values ??to zero. 4. Alcoholic beverages should not be consumed during medication, as they can cause the accumulation of acetaldehyde in the body, interfere with the oxidation process of alcohol, and lead to disulfiram-like reactions. Patients may experience abdominal cramps, nausea, vomiting, headaches, facial flushing, etc. 5. In patients with decreased liver function, the metabolism of this product slows down, and the drug and its metabolites are easy to accumulate in the body. The dosage should be reduced and the blood drug concentration should be monitored. 6. This product can be continuously cleared from gastric juice. Some patients who have a gastric tube placed for suction and decompression may cause a decrease in blood concentration. During hemodialysis, this product and its metabolites are quickly eliminated, so there is no need to reduce the dosage of this product. 7. If patients with Candida infection use this product, their symptoms will worsen and they need to be given antifungal treatment at the same time. 8. For patients with anaerobic bacterial infection and renal failure, the dosing interval should be extended from 8 hours to 12 hours. 9. When treating vaginal trichomoniasis, the sexual partner must be treated at the same time. 10. Before repeating a course of treatment, a white blood cell count should be done.