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? Brief introduction of Banxia Xiexin decoction
Banxia Xiexin Decoction comes from Treatise on Febrile Diseases and consists of Banxia, Coptidis Rhizoma, Scutellariae Radix, Glycyrrhrizae Radix, Zingiberis Rhizoma and Ginseng Radix. The whole prescription uses cold and heat to regulate yin and yang, bitter and bitter to restore ascending and descending, and tonic and diarrhea to regulate deficiency and excess, which is a prescription for treating the heart of cold and heat. This paper attempts to interpret this prescription from multiple angles and multiple effects, and to explore the essence of its function.

Modern medical interpretation of Banxia Xiexin decoction

Modern research shows that Pinellia ternata has the functions of relieving cough, inhibiting gland secretion, relieving vomiting, inhibiting trypsin, resisting cancer, regulating immunity and nerve excitability, and has certain anti-inflammatory effect by regulating immunity; Coptis chinensis and Scutellaria baicalensis Georgi, as representative drugs for clearing away heat and toxic materials, can stimulate the increase of intracellular calcium ions by inhibiting artificial tripeptide, promote the increase of intracellular adenosine phosphate level, further affect various functions of leukocytes, play an anti-inflammatory role, and adjust the level of immune function at the same time, especially for the hyperactivity of the body. Dried ginger, as an essential medicine for warming the middle energizer, has an obvious effect of warming and activating the middle energizer, and can improve the low-level state of body function: Ginseng, as the first choice for invigorating qi, has an exciting effect on the central nervous system, can enhance the immune function of the body, promote the establishment of collateral circulation, improve the blood supply of viscera, promote the secretion of hormones and improve the stress level of the body; The effective component of Glycyrrhiza uralensis Fisch is glycyrrhizin, which can repair the cell membrane, thus restoring the physiological function of cells.

From the above analysis, it can be seen that Banxia Xiexin Decoction has a simple formula, but it acts on the human body from the aspects of cells, hormone levels, blood supply, nerves, immunity and inflammatory reaction, and has a two-way regulation function, which can correct different body states, thus playing the role of regulating cold and heat, eliminating swelling and resolving hard mass.

State medical interpretation of Banxia Xiexin decoction

Banxia Xiexin Decoction was divided into bitter cold group: Coptidis Rhizoma and Scutellariae Radix; Ganwen group: ginseng and licorice; Xinwen group: Pinellia ternata and dried ginger. Through the study, it was found that the bitter cold group can reduce the inflammatory cell infiltration of gastric mucosa in mice and repair the cell mucosa through anti-inflammation, and the sweet warm group can regulate the body's immunity and restore the body's "steady state", and the effect of the whole prescription is better than that of the disassembled prescription group. Some scholars have found that Coptis chinensis and Scutellaria baicalensis can not only repair gastric mucosa, but also improve the atrophy of mucosal glands and kill Helicobacter pylori. Some scholars have tested the effects of Banxia Xiexin Decoction and its disassembled prescriptions on motilin in rats, and proved that dried ginger, ginseng and licorice can obviously enhance gastric motility and improve gastric emptying, while Pinellia ternata, Coptidis Rhizoma and Scutellariae Radix can improve the gastric cavity environment, and after Pinellia ternata, Coptidis Rhizoma and Scutellariae Radix improve the gastric environment, they can promote the absorption of dried ginger, ginseng and licorice, thus enhancing gastric motility. It is speculated that the reason for the pleiotropic effect of Banxia Xiexin Decoction lies in its composition characteristics, which is both sweet and bitter, and warm and tonic.

Banxia Xiexin Decoction not only has protective effect on gastric mucosa, but also can repair the colonic mucosa with ulcerative inflammation by affecting the expression levels of NO, NOS and TNF-a in colon tissue. It can be seen that its action site is extensive.

Multi-effect of Banxia Xiexin Decoction

Banxia Xiexin Decoction has been used by doctors in past dynasties to treat various diseases. The author has consulted a large number of literatures, and statistics show that there are more than ten kinds of diseases treated by it, such as chronic colitis, chronic superficial gastritis, atrophic gastritis, peptic ulcer, reflux esophagitis, functional constipation, functional abdominal distension, alcoholic colitis, diarrhea during pregnancy, chronic pyelonephritis, chronic cholecystitis, Meniere's syndrome, tinnitus, functional dyspepsia, chest obstruction, chronic cough, insomnia and acne.