1, cough and asthma: the bitter amygdalin contained in the lower gastrointestinal tract by intestinal microbial enzyme decomposition or by the amygdala itself contains bitter amygdalin enzyme decomposition, resulting in a trace of hydrocyanic acid, respiratory center inhibition, and to achieve the effect of suppressing cough and asthma. The bitter amygdalin 1 ~ 100mg / kg gavage, sulfur dioxide triggered cough in mice have inhibitory effect.
2, the effect on the digestive system: almond fat oil has laxative effect. Bitter amygdalin decomposition product benzaldehyde can inhibit the digestive function of pepsin.
3, anti-tumor effects: hot water extract of crude preparations of human cervical cancer JTC-26 strain inhibition rate of 50% to 70%; hydrocyanic acid, benzaldehyde, bitter amygdalin have a weak anticancer effect; to the mouse free ingestion of bitter almonds, can inhibit the growth of Ehrlich ascites carcinoma, and prolong the survival period.
4, anti-inflammatory and analgesic effects: almond globulin component KR-A40mg/kg, KR-B 5mg/kg, albumin component KR-A0.5mg/kg, AR-B 0.5mg/kg, intravenous injection, the keratine-induced foot-plantar swelling in rats has an inhibitory effect. Intravenous injection of amygdalin fractions KR-A5mg/kg and KR-B 5mg/kg, and albumin fractions AR-A5mg/kg and AR-B 0.5mg/kg showed analgesic effects on mice by the benzoquinone torsion method.
5, toxicity: oral administration of large quantities of bitter almond easy to produce poisoning, the first role in the medulla oblongata vomiting, respiration, vagus nerve and vasomotor centers, causing excitation, followed by coma, convulsions, and then the entire central nervous system paralysis and death; manifestations of vertigo, headache, shortness of breath, vomiting, palpitations, cyanosis, coma, convulsions and so on.