Drug treatment of constipation: 1. Functional constipation: lactulose is a synthetic disaccharide, which is rarely absorbed in the intestine and can be decomposed into lactic acid and acetic acid by bacteria, so that water and electrolyte remain in the intestinal cavity, resulting in high osmotic pressure difference, leading to dissolved defecation and gas production, which can significantly reduce the incidence of fecal impaction in the elderly. Take orally once 10~20g, once a day 1 time, or take orally 65% lactulose syrup once 10~40ml, and the maximum dose is 60ml a day. 2. Acute, chronic or habitual constipation: bisacodyl can be used to stimulate the sensory nerve endings of the intestinal wall through contact with the intestinal mucosa, causing the intestinal reflex peristalsis to be enhanced and discharging soft and shaped feces. Take 5~ 10mg once, and swallow the whole tablet before going to bed, but it will take effect 6~ 12 hours after taking it. 3. Hypotonic constipation: Glycerol suppository can be used, which can lubricate and stimulate the intestinal wall, soften the stool, make the stool easy to discharge, and has a mild effect. Once 1 pill is inserted into anus, once a day 1~2 times, which is more effective than 30 minutes after administration. Or mixed with sorbitol to make enema (Kaisailu), which not only has lubricating effect, but also stimulates rectal wall and reflects defecation, especially suitable for children and the elderly. 20ml for adults and 5~ 10ml for children, with anal injection. 4. Acute constipation: Magnesium sulfate is a volumetric laxative, which should not be absorbed orally. It stays in the intestinal cavity, which increases the osmotic pressure of the intestinal volume and prevents the absorption of water in the intestinal cavity. At the same time, it attracts the water in the tissue to the intestinal cavity, which increases the intestinal internal volume, stimulates the intestinal wall, reflexively increases intestinal peristalsis and leads to diarrhea, which has a strong effect and discharges a large number of watery stools. It can be used alone or in combination with sorbitol or glycerol. Adults should take 5~20g at a time, and children should take 1g once a week, and drink plenty of water at the same time. 5. Spastic constipation: optional polyethylene glycol powder, which can be easily dissolved in water to form viscous mucilage after taking, can lubricate the intestinal wall, soften the stool and adjust the consistency, so that the stool can be easily discharged. Less adverse reactions, less irritation. Oral administration for adults once 1~2 bags, dissolved in water. Another drug of the same kind is sodium carboxymethyl cellulose, which is easy to disperse in water to form a viscous colloidal liquid, which can lubricate the intestinal wall and absorb a lot of water. After spraying, it stimulates the intestinal wall, causing defecation and defecation. Take 2g orally for adults once, three times a day. Take it with warm boiled water. But the elderly should not take more than 2g a day.