Classification of adverse drug reactions:

According to the characteristics of the occurrence of adverse drug reactions, adverse drug reactions are usually divided into two categories: type A and type B.

(1) Type A adverse reactions are caused by the enhancement of the pharmacological effect of the drug.

(1) Type A adverse reactions are caused by the enhancement of the pharmacological effects of the drug, dose-related, generally with the increase in the dose of adverse drug reactions aggravated, which is characterized by predictable, high incidence and low mortality. Such as excessive action, first dose effect, side effects, toxic reactions, withdrawal reactions, secondary reactions, drug dependence, after-effects are A-type adverse reactions.

(2) B-type adverse reactions are not related to the normal pharmacological effects of the 'abnormal reaction, with the dose of the drug has nothing to do with, it is characterized by the general unpredictability, the incidence rate is low (<5%) and the mortality rate increases. Such as idiosyncratic reactions, anaphylactic reactions (type II), carcinogenic teratogenic mutation reactions, etc. are B-type adverse reactions.

Appendix:

Artemisia annua

Synonyms Artemisia annua, Artemisia herbacea, Artemisia fangcai, Artemisia stenchata, Artemisia aromata, Artemisia tridentata, Artemisia absinthium.

Origin and Sources The dried above-ground parts of Artemisia annua, family Asteraceae.

Compositional studies

(1) Sesquiterpenes Artemisinin, artemisinic acid, artemisinol, artemisinin, etc.

(2) Volatile oils linalool, isoborneol, etc..

(3) Flavonoids

(4) Coumarins Apocynin, lignans, etc.

Pharmacological effects

(1) Antimalarial effects: Artemisinin and derivatives are the main active ingredients in the role of Artemisia annua.

(2) Anti-pregnancy effect: artemisinin has a direct killing effect on the in vitro culture of human metamyelocytes.

(3) Anti-tumor effects: artemisinin and its derivatives have cytotoxic effects on mouse Ehrlich ascites tumor cells and human HeLa cells.

(4) Cardiovascular effects: including slowing the heart rate, inhibiting myocardial contractility, reducing coronary flow, lowering blood pressure, antiarrhythmic effects.

Sexual flavor attribution

Bitter, pungent, cold. Attributed to the liver and gallbladder meridian.

Functions and Indications

Clearing away heat, removing summer heat, removing vapor, and stopping malaria. It is used for acting evil fever, yin deficiency fever, night fever and early cold, bone vapor labor fever, malaria cold and heat, damp-heat jaundice.

Adverse reactions

A few cases of nausea, vomiting, abdominal pain and diarrhea. Artemisinin injection may occasionally cause allergic reactions.

Note on use

It should not be decocted for a long time.