Difference:?
1, both are H1 receptor blockers, the difference is that Dexloretadine is the active ingredient of Loratadine, which is more effective, just like Levofloxacin
star and Oxyfloxacin, the former is the active ingredient of the latter.
2, because some impurities have been removed, the side effects of desloratadine are much less than those of loratadine.
3, there is also a big difference in price.
Expanded Information
Cautions for Loratadine Tablets:
1, patients with severe liver insufficiency should be used under the guidance of a doctor.
2, pregnant and lactating women should be used with caution.
3, about 48 hours before the skin test should be discontinued use of this product, because antihistamines can prevent or reduce the occurrence of positive skin test.
4, allergic to the product is prohibited, allergic persons should be cautious.
5. The use of this product is prohibited when there is a change in its character.
6. Please keep this product out of the reach of children.
7, Children must be used under adult supervision.
8, If you are using other drugs, consult your physician or pharmacist before using this product.
9. The safety and efficacy of this product in children under 6 years of age have not been established, consult your physician or pharmacist.
10, liver and renal insufficiency should reduce the dosage, it is recommended that 10 mg, once every 2 days or under the supervision of a doctor.
11, because the plasma concentration of elderly patients after taking the drug is higher than that of healthy people, so elderly patients need to pay close attention to the occurrence of adverse reactions when long-term application of this product.
12, adults overdose of this product (40-180 mg) can occur drowsiness, arrhythmia, headache. As soon as these symptoms occur, give
symptomatic and supportive therapy. Therapeutic measures include emesis followed by administration of activated carbon to adsorb unabsorbed drug. If emesis is unsuccessful, the stomach is
washed with saline, diarrhea is administered to dilute the concentration of the drug in the intestines, hemodialysis does not clear loratadine, and it has not been determined whether peritoneal
dialysis can clear the drug.
Desloratadine Precautions
I. Because antihistamines clear or attenuate positive skin reactions to all allergens, use of this product should be discontinued
48 hours prior to any skin sensitization test.
II. Patients with hepatic injury, bladder neck obstruction, urethral hypertonia, prostatic hypertrophy, and glaucoma should use the drug as prescribed.
Three, pregnant and lactating women use: given 34 times the human clinical recommended dose of diclofenac tadalafil, was not found to have an effect on the overall fertility of rats
.
1. No teratogenic or mutagenic effects of Desloratadine have been observed in animal studies. Because there are no clinical data on the use of desloratadine in pregnant women,
the safety of desloratadine in pregnancy has not been established, and desloratadine should not be used in pregnancy unless the potential benefits outweigh the possible risks.
2,
The use of desloratadine has been shown to be associated with a decrease in the number of women who are pregnant.
2. Desloratadine is excreted in breast milk; therefore, desloratadine is not recommended for nursing women.
4. Pediatric Use: The efficacy and safety of desloratadine in pediatric patients under 12 years of age have not been established.
V. OVERDOSAGE: Standard therapeutic measures to remove unabsorbed active ingredients should be considered in overdose publications. Symptomatic and supportive
treatment is recommended.
1, in a multi-dose clinical trial in adults and adolescents, subjects received up to 45 mg of diclofenac tadalafil (9 times the clinical
interim dosage), no adverse effects were observed clinically, but there was a possibility of prolongation of the Q-Tc interval on the electrocardiogram.
2, Dicloretin can not be eliminated by hemodialysis; whether it can be eliminated by peritoneal dialysis is not known.