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What is the mechanism of hepatoprotective effect of Yin Chen?

Yin Chen is a Chinese herbal medicine, which is mainly effective in the treatment of jaundice, infectious jaundice hepatitis. In the treatment of hepatitis, Yin Chen not only has an anti-inflammatory effect, but also has a hepatoprotective effect, let us understand What is the mechanism of hepatoprotective effect of Yin Chen?

What is the mechanism of hepatoprotective effect of

Inchcape has a significant hepatoprotective effect on hepatitis A, B, jaundice hepatitis, has a significant therapeutic effect. It is beneficial to bile, promote bile secretion, increase the discharge of bile bile acid and bilirubin. It can increase coronary blood flow, improve microcirculation, and has the effect of lowering blood pressure, lowering blood lipids, anticoagulant, diuretic, antipyretic and asthma, expel roundworms and inhibit a variety of pathogenic skin fungi and bacteria.

The decoction of Yin Chen has a good protective effect against acute liver injury in rats caused by CCl4, and its mechanism may be related to the inhibition of peroxidation in vivo.

Certain flavonoid and coumarin components of Yin Chen have anti-CCl4 or galactose-induced cytotoxicity in rat hepatocytes, and their strengths are, in order, Yin Chen chromone, scopolamine, 6,7-dimethoxycoumarin, Yin Chen flavonoid, quercetin, and isorhamnetin. The active ingredients in the compound formula of Artemisia capillaris sinensis soup very significantly reduced the serum glutamic transaminase (SGPT) and glutamic oxal transaminase (SGOT) levels in acutely jaundiced rats, while the effect on serum bilirubin (SB) was less pronounced. In addition, 6,7-dimethoxycoumarin has a strong inhibitory effect on hepatocyte damage.

The efficacy and role of the therapeutic dietary supplement of Yin Chen

1, antipyretic. The decoction has a strong antipyretic effect, but the decoction of antipyretic effect is weaker.

2, choleretic. It can promote the secretion of bile, and the active ingredients are chlorogenic acid and caffeic acid.

3. Antibacterial. In vitro test on Staphylococcus aureus has antibacterial effect.

4, antiviral. It has strong inhibitory effect on influenza virus (PR8 strain).

5, anti-fungal. Diluted 4 million times, it can still inhibit the development of scarlet Trichophyton rubrum, the active ingredient is inoculin.

6, lipid-lowering. Can reduce serum cholesterol and apolipoprotein B, to prevent lipid accumulation in the blood vessel wall.

Clinical application of Inoceramides: the main drug for the treatment of jaundice.

1, the treatment of damp-heat jaundice, used for Yang Huang (yellow sharp as orange color, most commonly seen in acute jaundice infectious hepatitis, cholecystitis, etc.), taking its role in promoting bile secretion and excretion. At the early stage of jaundice, heat is heavier than dampness, with fever, dysuria, constipation, abdominal distension and fullness, pulse stringy, with gardenia, rhubarb to strengthen the role of clearing heat and diarrhea, put into the Artemisia capillaris soup. If dampness is more important than heat, with fullness in chest and epigastric region, heavy head and sleepy body, stool is not constipated, but urine is not favorable, pulse is moist and slow, then it should be matched with Wu Ling San, such as Yin Chen Wu Ling San.

2, the treatment of cold and damp jaundice, used for yin yang (yellow dark like smoke, mostly seen in chronic jaundice infectious hepatitis, hepatic cirrhosis and other diseases), there is a systemic cold and dampness of the evidence, this time to be matched with the warming of cold medicine such as epiphyllum, ginger, etc., in order to warm the cold and dampness, such as the Yin Chen Sibiyei San.

3, as a substitute for chaihu used to clear heat. Both Yin Chen and Chai Hu have the effect of removing heat, and Chinese medicine experience suggests that both medicines enter the liver and gallbladder, and can remove the actual fire of the liver and gallbladder. However, the medicinal properties of Yin Chen are slightly softer than those of Chai Hu. Therefore, if you have a deficiency of Yin and a new solid heat, and you need to use Chai Hu to clear the heat, but you can't accept the dryness of Chai Hu, you can use Yin Chen to replace Chai Hu.

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