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Different names are Acanthopanax senticosus, Periploca paliurus (Scientific Folk Herbs), Acanthopanax odorus (Shandong Traditional Chinese Medicine), Acanthopanax senticosus (Records of Traditional Chinese Medicine in Shanxi) and Acanthopanax fragrans (Records of Traditional Chinese Medicine in Sichuan).

The source is the root bark of Periploca periploca of Asclepiadaceae.

Plant morphology: Periploca angustifolia, goat's milk, Sophora japonica, Sophora japonica, and cross leaves of sheep.

Deciduous leaves wrap around shrubs, reaching as high as 1 m or more. The taproot is cylindrical. Branchlets are often opposite, yellow-brown, with fine stripes and lenticels with dot-like protrusions on the branches. Leaves opposite, petiole 3 ~ 6 mm long; The leaf blade is lanceolate or oblong, 5 ~10cm long and1~ 3cm wide, the apex is tapering, the entire, the base is wedge-shaped or nearly round, the upper part is dark green and shiny, the lower part is light green, and the pinnate veins are fine. Cymes axillary or terminal, with one to several flowers; Bracts opposite, small; Pedicel slender, flower diameter about 2 cm; Calyx deeply 5-lobed, lobes ovate; Corolla is greenish yellow outside, purplish red inside, deeply 5-lobed, lobes are oblong, rolled outward, and the edges are densely covered with white hairs; Corona 5, linear, puberulent; Stamens 5, coniform, hairy, surrounding pistil; The ovary is superior and consists of 2 separate carpels, and the stigma is United. Follicle is nearly cylindrical, with a length of10 ~15 cm and a sharp apex. The two fruits are opposite, curved and connected at the top, and longitudinally split along the inside when hot. The seeds are narrow, spindle-shaped and flat, dark brown, with long white hairs clustered at the top. Flowering in May. The fruiting period is September.

Growing on dry slopes, sandy slopes and gravelly slopes. Distributed in Jilin, Liaoning, Inner Mongolia, Hebei, Shanxi, Henan, Shaanxi, Gansu, Ningxia, Sichuan, Shandong, Jiangsu and other places.

Collecting can be done in spring and autumn. Beat with a wooden stick while it is fresh to separate the root bark from the xylem, remove the wood core, and dry the bark in the shade or in the sun.

The dried skin of medicinal materials is long cylindrical, single-rolled or double-rolled, and a few are trough-shaped or fragmented, with a length of 16 cm and a thickness of 2 ~ 5 mm. The outer surface is grayish brown or earthy brown and reddish, rough, with long lenticels, and the cork is often peeled off in scales, sometimes revealing the earthy brown skin; The inner surface is grayish yellow or earthy brown. It is hard and brittle, and the broken surface is slightly flat. It has a strong special aroma, which makes people dizzy after long-term smelling; It tastes bitter. It is better to have thick strips, thick skin, roll shape, no wood core, thick aroma and bitter taste.

Location: Shanxi, Henan, Hebei and Shandong. In addition, Sichuan, Gansu, Hunan, Liaoning, Jilin, Jiangsu and other places also produce.

This product is used as acanthopanax bark in various places, but it is toxic, and its properties are different from acanthopanax bark, so it should be used differently. See article "Cortex Acanthopanacis".

The chemical constituents of stem bark and root bark contain more than ten kinds of glycosides, among which cardiac glycoside periplocin and saponin periplocin K, H 1, E are known. It also contains 4- methoxysalicylaldehyde, α-geraniol, β-geraniol, α-geraniol acetate, β-geraniol acetate, β-sitosterol and its glucoside.

Pharmacological action ① cardiotonic effect

Periploca Periploca preparation (water-soluble substance extracted with ethyl ether and ethanol) stops the heart of in-situ frog in contraction phase, the blood pressure of in-situ cat increases, the contractility of heart increases, and the minute output of exhausted cat heart (cardiopulmonary device) increases. The skin extract B (extracted by chloroform and ethanol) has also been proved to have a general cardiac glycoside effect in the heart and ECG experiments of in-situ cats. Ascoside and Ascoside from the root bark of Greek Periploca Periploca have quick action, short duration and weak accumulation.

② Sedative action

Periploca Periploca extract B has no sedative effect on mice, while Periploca Periploca tincture and Periploca Periploca solution all show central excitement, which may be caused by its volatile components.

③ Other functions

Ascleoside can increase pulmonary circulation under certain conditions. Clinically, strengthening the heart is beneficial to the defecation. In addition, Periploca paliurus has insecticidal effect.

④ Biological activity

The cat unit of Periploca Periploca preparation is 0.176g. Periploca Periploca extract B is 1.6 mg/kg. Ascleoside 1 g contains 5780 cat units, which has low accumulation and shorter action time than that of strophantoside G.

Toxicity: The root bark of Periploca Periploca (North Acanthopanax) is used to replace the southern Acanthopanax (bark or root bark of Acanthopanax or Acanthopanax of Araliaceae). Care should be taken when making acanthopanax bark wine, because acanthopanax bark has a strong cardiotonic effect, and it is easy to be poisoned if used too much. Injected into animals, it can make their blood pressure rise extremely high, and it can kill them in about 3 ~ 20 minutes; The cortex acanthopanacis is mild, and the blood pressure has not changed much after injection.

Processing, cleaning impurities, washing with water, moistening, cutting, and drying.

It tastes bitter, slightly warm and toxic.

① Annals of Sichuan Traditional Chinese Medicine: "Mild in nature, sweet in taste and toxic."

② Handbook of Hebei Traditional Chinese Medicine: "Warm in nature and pungent in taste."

③ Selected Chinese Herbal Medicines from Shaanxi, Gansu and Ningxia: "Bitter and pungent in taste, warm in nature and toxic."

Functions are mainly used to dispel wind and dampness and strengthen bones and muscles. Treat rheumatoid arthritis; Children's muscles and bones are weak, and their feet are flaccid and late; Edema is not good for urination.

① Annals of Sichuan Traditional Chinese Medicine: "Analgesia and rheumatism. Treat arthralgia due to wind-cold and dampness, contracture of feet and knees, and pain of bones and muscles. "

② Selection of Shaanxi-Gansu-Ningxia-Qinghai Chinese Herbal Medicine: "Expelling wind and dampness, strengthening bones and muscles, and strengthening waist and knees."

Usage and dosage for oral administration: decoction,1.5 ~ 3 RMB; Soak in wine or take pills or powder.

The Annals of Sichuan Traditional Chinese Medicine should be avoided: "Those with blood heat and hyperactivity of yang should not use it."

Prescription ① Treatment of rheumatoid arthritis and arthralgia due to contracture: five yuan for Cortex Acanthopanacis, five yuan for Rhizoma Dioscoreae Nipponicae and five yuan for Cortex Dictamni. Soak in white wine for 24 hours. Take10ml daily.

② Treatment of weakness of bones and muscles, delayed foot paralysis: Cortex Acanthopanacis, Fructus Chaenomelis, Radix Achyranthis Bidentatae, etc. One yuan for each dose, three times a day.

③ Treatment of edema and unfavorable urination: Cortex Acanthopanacis, Pericarpium Citri Tangerinae, Cortex Zingiberis Recens, Poria cocos and Pericarpium Arecae are San Qian each, and decocted with water. (① Selected Chinese Herbal Medicines from Shaanxi, Gansu, Ningxia and Qinghai are listed below)

④ Treatment of edema: Cortex Periplocae costs one yuan and five cents to San Qian. Decoct. (Common Chinese Herbal Medicines in Shanghai)

Reminder: Cortex Periplocae, a Chinese herbal medicine, comes from the Internet. Please follow the doctor's advice before using it.