Pharmaceutical formula of amethyst tablets
Zijing tablet is a traditional emergency medicine. The prescription consists of 60g of Shā rotto Katakuri, 45g of vinegar-roasted Euphorbia humifusa, 30g of Euphorbia humifusa, 30g of Chinese gall, 9g of musk, 9g of cinnabar and 6g of realgar. This recipe has the effects of resolving phlegm, inducing resuscitation, removing dirt and toxic materials, and relieving swelling and pain. The musk in the prescription is fragrant to enlighten the senses, promote qi circulation and relieve pain; Shā rotto Katakuri clears away heat and detoxifies; Realgar detoxifies filth; Qianjinzi ointment and Euphorbia humifusa are used to eliminate phlegm and reduce swelling; Cinnabar calms the nerves; Galla chinensis astringent intestine to stop diarrhea. The combination of all kinds of drugs can enlighten the senses, eliminate phlegm, ward off evil spirits and detoxify, and has the effect of slowing down the downward trend, while external use has the effect of reducing swelling and resolving hard mass.
The preparation method of purple wafer is as follows: mixing cinnabar and realgar respectively, flying in water or pulverizing into superfine powder; Pulverizing Shā rotto Katakuri, Galla Chinensis and Stellera chamaejasme into fine powder; Pulverizing Moschus, mixing with the above powder and Radix Sophorae Flavescentis cream, sieving, and mixing. Another 90 grams of glutinous rice flour was added with tap water to make a block, steamed, soaked in medicinal powder, pressed into ingots (blocks), dried in the shade, and the weight of the ingots (blocks) was 3 grams.
Clinical application of purple chip
The traditional treatment scope of purple chip mainly includes three aspects.
1, Cholera bloating: Most of them are due to the pathogen of dampness and turbidity in summer, blocking the middle energizer, disordered qi movement and abnormal ascending and descending, resulting in vomiting and diarrhea, or abdominal pain, such as colic, vomiting, diarrhea, irritability, unconsciousness, and even pale face, cold limbs, head sweat and heavy pulse.
2, children with phlegm-heat eating syncope: mostly due to children eating, stopping breastfeeding, phlegm-heat stagnation, phlegm-heat upwelling, causing liver wind to cause high fever, fainting, throat ringing, full abdomen, heavy breathing, red tongue with thick yellow coating, slippery pulse.
3, carbuncle treatment of sores: mostly due to exogenous six evils, overeating fat and sweet, internal depression, damp heat and fire poison; Or trauma, toxic gas exposure, accumulation of pathogenic toxin, disharmony between camp and health, obstruction of meridians, stagnation of qi and blood, resulting in redness, swelling, heat and pain in the affected area. In severe cases, aversion to cold and fever, headache, yellow and greasy tongue coating, and rapid pulse may occur.
The contraindications and clinical efficacy of the capsule after the dosage form reform are briefly described as follows:
1, vomiting or diarrhea caused by food poisoning or drug poisoning; Swallow 3 grams with cold water and you will be cured.
2, carbuncle back, furuncle, parotitis, lymphadenitis, external application with warm water or wine, a few times a day can be eliminated.
3, diarrhea, dysentery, dysentery, cholera, 9 grams of mint decoction, 0.6 grams of Zijing once, 2~3 times a day.
4, suffering from digestive tract cancer caused by dysphagia, phlegm and saliva, dripping water is difficult to enter, you can use this product, swallow less (do not take it with water). Generally, after taking 3 grams, phlegm and saliva are reduced and swallowing obstruction is improved. Can take liquid diet, with other anticancer drugs, can prolong the life of patients.
5, heartburn with yellow wine, 0.6 grams each time, three times a day, its effect is good.
6, burns, fire injuries, scorpions, bee bites caused by local redness and pain, with cold water to adjust the powder coated on the affected area, and according to the dose of oral, its effect is remarkable.
7. For injuries from falls, you can take it with pine knots and fried wine.
8. For toothache caused by wind and fire and toothache caused by insect fire, apply wine to the sore spot and take this product orally.
9. It is used for infantile convulsion, malnutrition, dysentery and meningitis. It can be taken with warm boiled water (children's dosage is halved or adults' dosage is 1/3~ 1/4) twice a day for three days, which can clear away heat, refresh oneself, relieve pain, stop vomiting, eliminate phlegm and promote fluid production.
10, headache due to head wind, and sticking wine and medicine on both temples has analgesic effect.
Clinical study of purple chip
The modern research of purple gold ingot has made gratifying progress. Tang Youjun and others found that purple chip has obvious inhibitory and killing effects on leukemia cells in experimental leukemia mice. The drug mainly acts on S phase of stem cell cycle, and has the function of relieving and alleviating the invasion of leukemia cells on liver and spleen, thus significantly prolonging the survival time of leukemia mice. Wang Huanting's clinical study found that although the effective rate of treating children's epilepsy with purple chip was not much different from that of general antiepileptic western medicine, no clinical side effects were found in 50 cases, and 50 cases 16 cases were cured within 0.2 months, which is incomparable to existing antiepileptic western medicine. Especially 1 1 cases of children who don't get sick after taking the medicine are especially valuable. Wang Huanting then studied 105 cases of children who were ineffective in western medicine treatment. Choosing Zishen Tablet or Zishen Tablet (improved from Ziwei Tablet and Sophora Flavescentis) for treatment can achieve the effect of curing or prolonging intermittent attacks. Yue Yuxin and others found that purple chips can really reduce eosinophils. Fan et al. reviewed the clinical research in recent 30 years and found that Zijing ingot has a wide range of functions and has been used for:
1, internal medicine: including meningitis, esophageal cancer, atrophic gastritis, acute vomiting, eosinophilia, etc.
2. Pediatrics: used for epilepsy, bacillary dysentery, mumps, ascaris and pediatric emergencies.
3, surgery, dermatosis: used for drug-induced phlebitis, acute suppurative infection of skin and soft tissue, tinea.
4. Laryngology: used for acute tonsillitis, pharyngitis and chronic pharyngitis.
It can be seen that the purple gold ingot has a definite curative effect and is a treasure left by our ancestors, which deserves our serious and in-depth study and improvement.
Prescription reform of purple chip
Buccal tablets are an ancient traditional dosage form, mostly in the form of long strips and blocks, which are convenient for grinding juice for internal or external use. After grinding juice, it does not need to disintegrate in vivo, and its absorption and drug effect are fast, so it can be used for emergency use. Generally, buccal tablets are hard and dense, the inner layer is not easy to rot and deteriorate, and the effective components are not easy to volatilize and lose, which is convenient for storage and carrying. In ancient times, buccal tablets were an ideal dosage form. But today, buccal tablets have become more and more backward:
1. Inconvenient production: complicated process, manual operation, complicated preparation and low efficiency.
2. It is inconvenient to use: whether it is for internal use or external use, you should grind the juice every time.
3, the dose is not allowed: the dose is estimated by the patient himself, and it is not easy to master when grinding water.
4. It is difficult to meet the hygiene requirements: the production cycle is long, there are many manual operations, and the grinding water of hand-held spindle is easy to be polluted.
5, the raw powder of medicinal materials is directly used as medicine, which is easy to bring in a variety of microorganisms and eggs. These shortcomings seriously hinder the production and clinical application of purple chips.
In order to explore the precious heritage of traditional Chinese medicine, the reform of amethyst tablet form is imminent. It is ideal to change buccal tablets into powder capsules. The main features are as follows:
1, which retains the characteristics and advantages of traditional buccal tablets: it can be taken orally and applied externally; Oral administration does not require disintegration time and takes effect quickly.
2. Convenient production: simple process and high production efficiency.
3, easy to carry.
4. Accurate measurement.
5. It is easier to control the sanitary quality: the production cycle is shortened, and there is no need to expose in the shade for a long time or dry at low temperature, and there is no need to grind juice with hands when using it, thus reducing the chance of pollution.
6. The dosage can be reduced by reducing or not adding excipient (glutinous rice flour).
7. By strengthening the pretreatment of medicinal materials and using cobalt 60γ -ray irradiation sterilization, the problem of bacteria carrying in raw powder of medicinal materials can be solved.