Gout can not be cured, in addition to medication, we need to strengthen the prevention of gout and hyperuricemia, adjust the dietary structure, and avoid overwork, stress, cold and wet, joint injury and other triggering factors.
First of all, it is recommended to take early and sufficiently, colchicine, indomethacin, diclofenac, celecoxib, hormones in the acute attack of gout can relieve symptoms.
Aspirin should be used with caution in patients with renal insufficiency, previous peptic ulcers, bleeding, and perforation, and renal insufficiency also avoids the use of colchicine, which is used to select etoricoxib or celecoxib during an attack, and glucocorticosteroid therapy is recommended for systemic gout only when an acute gout attack involves multiple joints, large joints, or a combination of systemic symptoms.
Here to remind you, the first choice of non-steroidal anti-inflammatory drugs, such as indomethacin, diclofenac, celecoxib, for the first line of medication, colchicine for the traditional drugs, because of the many side effects, is currently less application, when intolerance of non-steroidal anti-inflammatory drugs and colchicine and renal insufficiency, consider the application of glucocorticosteroids.
Especially for patients with chronic renal insufficiency, febuxostat is recommended as an alternative to allopurinol, and now that the price of febuxostat has dropped, febuxostat is recommended as a first-line uric acid-lowering drug for gout patients.
For high uric acid caused by decreased uric acid excretion, benzbromarone is recommended. However, it is not recommended for patients with increased uric acid synthesis or at high risk of kidney stones. Benzbromarone should also be used with caution in patients with comorbid chronic liver disease.
Patients who do not reach the standard for uric acid despite adequate dosage of one drug and an adequate course of treatment may be considered for a combination of two uric acid-lowering drugs with different mechanisms of action.
Studies have shown that blood uric acid control at <360 μmol/L, and long-term maintenance, can reduce the number of gout attacks, so it is recommended that gout patients do not casually discontinue the use of uric acid-lowering drugs.
Gout attacks as long as the painkillers (such as celecoxib) after eating, the symptoms can most likely be quickly relieved; even if nothing is used, the pain symptoms in two weeks basically can also be relieved.
But pain relief does not mean the disease has been cured, if you do not correct the hyperuricemia, it will not stop the joints, kidneys and cardiovascular damage, so the gout symptoms after the relief of uric acid treatment is a protracted battle.
So, with gout, we must have a clear understanding of when to take medication, and how to take medication, so that we can stabilize the condition and reduce the distress caused by gout! I hope everyone can control the pain that gout brings to everyone!