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What are the effects and functions of Platycodon grandiflorum

Declaring the lung, expelling phlegm, inducing diaphoresis, and draining pus. Platycodon grandiflorum is bitter, pungent and neutral in nature. It is a good remedy for the lungs, and can be used to expel phlegm and expel pus. It is also used to regulate qi, activate blood circulation, eliminate food, and calm the mind.

The effect of Platycodonopsis: cough and phlegm, chest tightness. This product is pungent, bitter and excretory, to open the lung qi, expectoration, regardless of heat and cold can be applied. Wind-cold, with perilla, almonds, such as apricot-suzuan ("Articles on Warm Diseases"); wind-heat, with mulberry leaves, chrysanthemums, almonds, such as mulberry and chrysanthemum drink ("Articles on Warm Diseases"); if the treatment of phlegm and chest plumpness, often with hedgehogshells with.

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Expectorant and antitussive effects: anesthetized dogs orally administered with 1g/kg of decoction of this product can significantly increase the secretion of respiratory mucus, and its strength can be compared with that of ammonium chloride. The anesthetized cat also has obvious expectorant effect. Platycodonis saponins contained in the oral administration of the pharyngeal mucosa and gastric mucosa caused some degree of stimulation, reflexively cause respiratory mucosal secretion hypersecretion, so that sputum dilution, prompting its discharge, crude Platycodonis saponins have an analgesic effect. Guinea pig intraperitoneal injection and suppress cough half effective amount of 6.4mg/kg.?

Hypoglycemic effect: rabbit gavage of Platycodon grandiflorus water or alcohol extract 200mg/kg can make blood glucose drop, the water extract of the hypoglycemic curve is similar to the gavage of 25 ~ 50mg/kg of methylsulfonylurea. Water and alcohol extract 500mg/kg gavage for 4 consecutive days, the experimental tetroxine diabetic rabbits also have hypoglycemic effect, reduced liver glycogen in the drug is also seen in the recovery, and can inhibit the rise in food glucose, alcohol extract of the role of the water extract is stronger than that of the water extract.

Effects on the circulatory system: rats with crude Platycodonopsis saponins intravenous injection, can be seen in the temporary drop in blood pressure, heart rate slowing and respiratory depression. On the isolated guinea pig heart ear, high concentrations of negative inotropic effect. Anesthetized dogs arterial injection of 200-800mg/kg crude platycodonin, can reduce the resistance of coronary artery and nephrogenic blood vessels, increase blood flow, the intensity of which can be compared with opium poppy alkaloids. When 4mg/kg intravenous injection can also increase coronary artery and hind limb blood flow, and accompanied by temporary hypotension. This vasodilation is thought to be a direct effect on the peripheral vasculature.

References:

. p>Platycodonopsis_Baidu Encyclopedia