1, bacteriostatic effect: with the plate hole method, proved that the ink early lotus on Staphylococcus aureus, typhoid culm bacteria, Sung's dysentery bacillus, Pseudomonas aeruginosa has bacteriostatic effect.
2, hepatoprotective effect: ink early lotus of benzene, acetone, petroleum ether and 50% ethanol extract of carbon tetrachloride caused by liver injury have protective effect, which 50% ethanol extract of the strongest effect. In the carbon tetrachloride-induced rod damage model in mice and rats, AST (aspartate aminotransferase), ALT (alanine aminotransferase), total protein, total bilirubin and sulphonyl bromide titanium clearances rise and other indicators to observe, showing that the ethanol extract of the ink Early Lotus on the liver function has a significant protective effect.
3, the effect on immune function: ink lotus decoction to 10g/kg and 20g/kg mice gavage, can significantly increase the weight of young mice thymus, improve the rate of carbon granule contouring and peripheral blood leukocyte number; significantly increase the degree of 2,4-dinitrochlorobenzene (DNCB) due to the swelling of mice ears, and sheep red fine growl (SRBC) convergence of mice delayed hairstyle It also significantly increased the percentage of T lymphocytes in peripheral blood, while it had no significant effect on the antibody function of spleen secretion and serum hemolysin antibody content in mice. The above results indicate that the ink lotus can significantly enhance the non-specific immunity and cellular immunity, and it seems to have no effect on the humoral immunity. The 20% allyl alcohol extract of L. murraya significantly promoted the value-added of T and B lymphocytes, and the monomer compound S2S3S8 significantly promoted the transformation of lymphocytes and increased the production of interleukin II.
4, anti-mutagenic effect: the water-soluble extracts of Melaleuca alternifolia, 7.5g/kg, 15g/kg, 30g/kg, were given to mice by gavage or intraperitoneal injection, and all of them had obvious inhibitory effect on cyclophosphamide-induced erythrocyte micronuclei, indicating that the drug has a certain protective effect on chromosome damage. This anti-mutagenic effect and the enhancement of immune function may be part of the pharmacological basis of the drug in tonifying the kidney and prolonging the aging process.
5, the effect on the cardiovascular system: the Murraya can make the guinea pig flesh heart coronary flow increase, well make the electrocardiogram T-wave changes, mice, whether in normobaric or decompression hypoxia, can be significantly prolonged life or improve the survival rate; the role of the Murraya extract in clinical trials in the coronary heart disease, angina pectoris cases have a certain efficacy in line with the Murraya.
6, hemostatic effect: the dog's femoral artery half cut off, with the ink early lotus leaf powder on the bleeding place, and a little pressure, there is a good effect of hemostasis, the water extract also has a significant hemostatic effect.
7, other effects: ink early lotus decoction of esophageal cancer 109 cells have a moderate degree of killing effect. In addition, the ink early lotus has obvious sedative and analgesic effect on mice. The ethanol extract of Murraya lanceolata can significantly reduce the carbon tetrachloride-induced increase in cyclohexabarbital sleep time and the increase in chlorphenazolamide paralysis time. Araliaceae - Toxicity and Side Effects The LD50 for mice administered by gavage is 163 +- 21.4 g/kg, with a safety factor of 700-750 times. Murray drought lotus aqueous extract 5g/kg gavage for 7d, did not see the mouse bone marrow multi-stained erythrocytes and organic cells of the micronucleus rate increased, indicating that the Murray drought lotus on the chromosome has no detrimental effect on the non-mutagenic.