Pharmacological effect: 100% decoction has inhibitory effect on rabbit heart in vivo, which weakens myocardial contractility and reduces its frequency. In vivo and in vitro, toad's heart is slightly enhanced, but it has diastolic dysfunction. Dropping on toad mesentery can dilate arterioles, even if they are contracted with adrenaline first. It can lower the blood pressure of anesthetized rabbits and dogs, and its hypotensive principle seems to be related to vagus nerve.
Sexual taste: bitter; Cold nature.