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Causes of leukopenia
Question 1: What causes leukopenia Which types of leukopenia need treatment

? White blood cells in the blood are the body's defense against bacterial invasion patrol soldiers. When bacteria and other foreign invasions, white blood cells will enter the invasion site, the bacteria surrounded, engulfed, eliminated, so the white blood cells have the human body "white guards" called. It can be seen that a decrease in the number of white blood cells will weaken the body's antimicrobial capacity, susceptible to infection. However, the reduction of white blood cells does not necessarily have to be treated, one depends on the degree of reduction; the second depends on the reason for the reduction.

? The normal white blood cell count is (4 to 10) × 109 / liter, commonly known as 4000 to 10,000 per cubic millimeter, the average value of 7000. If it is between 4,000 and 7,000, it is low normal and does not require treatment; if it is below 4,000, leukopenia is diagnosed. Even so, it does not necessarily mean that treatment is needed. For example, if the decrease is only mild or transient, does not continue to fall on retesting, and there are no symptoms or discomfort, then there is no need to be nervous and no treatment is needed. Of course, white blood cells in the following cases need to be concerned, and under the guidance of the doctor, take intervention measures.

? 1, a severe decrease in white blood cell count requires urgent treatment. White blood cells are made up of granulocytes, lymphocytes, monocytes, and so on. Generally speaking, the most common and the most important white blood cell reduction is the reduction of granulocytes, if the degree of reduction is too obvious, the bacteria is likely to be in the body completely or basically the state of loss of resistance to spread rapidly, and even into the bloodstream triggered sepsis, a serious threat to life.

? 2, there is a reason to find the leukopenia should be directed at the cause of treatment. Common causes of leukopenia are generally three types: one is drugs, such as taking antipyretic drugs, sulfonamides, etc., at this time, such as leukopenia is too obvious, you should stop or change the drug; two is a viral infection, such as influenza, viral infections, etc., at this time, on the one hand, should be active in the antiviral treatment, the other hand, can be taken as appropriate, to increase leukocytes of the drug; three is suffering from immune system diseases, such as rheumatoid arthritis, etc., at this time, the immune system can be used for the treatment of the disease. The third is suffering from immune system diseases, such as rheumatoid arthritis, etc., at this time should also make the same intervention, choose to take the drugs that can increase white blood cells.

? 3, at the same time there are red blood cells and (or) thrombocytopenia need further diagnosis and treatment. When there is a decrease in white blood cells, if there are abnormal changes in the other two types of cells in the blood, i.e., red blood cells and platelets, the problem is more complicated, first of all, we need to further examination, the most commonly done is bone marrow examination to rule out the presence of other blood diseases, and then decide on the treatment plan.

? Clinically used drugs to raise white blood cells are: vitamin B4, lisinopril, shark liver alcohol, coenzyme A, etc., generally without any side effects. Patients can choose them under the guidance of the doctor.

Leukopenia and granulocyte deficiency

Leukopenia and neutrophil deficiency are a group of syndromes caused by a variety of causes. According to their clinical characteristics, they belong to the category of "qi deficiency" in Chinese medicine.

[Clinical manifestations]

1. Leukopenia: general dizziness, fatigue, limb weakness, loss of appetite, low fever, insomnia and other non-specific symptoms. A small number of asymptomatic, some patients are recurrent oral ulcers, lung infections or urinary tract infections.

2. Granulocyte deficiency: the onset of the disease is acute, often with high fever, chills, headache, fatigue or extreme weakness. Sometimes the oral cavity, nasal cavity, skin, rectum, ***, *** and other mucous membranes can appear necrotic ulcers. For those who are allergic to the drug, exfoliative dermatitis may occur at the same time, and in severe cases, central nervous system symptoms may occur. Septicemia or septicemia often occurs rapidly and leads to death.

[Diagnosis]

1. Leukopenia: peripheral blood leukocyte count is less than 4.0xll09/L for various reasons. In children

, the standard is less than 4.5x109/L for 10-14 years old, 5.0x 109/L for 5-9 years old, and 5.5x 109/L for less than 5 years old.


2.

2. Neutropenia and granulocyte deficiency: the absolute value of peripheral blood neutrophils is less than 2.0x109/L in adults, which is called neutropenia; less than 0.5xl09/L, which is called neutropenia.

[Treatment]

1. Western medicine

(1) Leukocyte-boosting drugs, such as leukocytes or vitamin B410mg, 3 times a day; or lithium carbonate 0.25 grams, 3 times a day.

(2) Use G-CSF and GM-CSF to promote cell production.

2. Chinese medicine treatment

Qi and blood deficiency: shortness of breath and weakness, dizziness, limb weakness, loss of appetite, insomnia and dreaminess, or extreme weakness, frequent occurrence of colds or other infectious syndromes, with a pale tongue and white moss, and a thin and weak pulse.

Treatment: tonifying qi and blood.

Prescription: Codonopsis, Astragalus 30 grams each, Huang Jing, Chen Pi, Atractylodes Macrocephala, Radix et Rhizoma Gastrodiae, Radix Rehmanniae Praeparata, Angelica Sinensis, Radix Paeoniae Alba, Salviae Miltiorrhizae, 10 grams each, Licorice 6 grams, Da ...... >>

Question 2: What causes low white blood cells? Most of the time it is due to drugs, radiation, infections and other bacteria that cause a decrease in granulocytes. The decrease in white blood cells often leads to a decline in the body's immunity, and traditional Chinese medicine believes that the early stages of the disease are mostly two deficiency spleen qi loss, and the late stage of the injury to the liver and kidney, resulting in kidney yin deficiency.

Question 3: What are the causes of leukopenia? What is the value of white blood cells?

Taking peripheral blood from the finger or earlobe to check the white blood cell count, if the total number is less than 4×109 per liter (4000/cubic millimeter), it becomes leukopenia. It is a group of diseases caused by many reasons.

To understand the causes of leukopenia, it is important to understand the process of granulocyte differentiation and maturation. Normal mature granulocytes have hematopoietic totipotent stem cells, via myeloid stem cells, granulocyte C monophyletic progenitor cells, as well as progenitor, early juvenile, juvenile, late juvenile granulocyte differentiation and maturation. Late granulocytes and mature granulocytes (rod-shaped and lobulated nuclei) no longer divide and accumulate in the bone marrow as a supplement and reserve. Approximately 1.5109/kg body weight of mature granulocytes enter the walls of peripheral blood vessels each day. The granulocytes that enter the blood circulation last only 8 hours and, as needed, can penetrate capillaries and then enter tissues and organs. Most of the granulocytes are excreted through the mucous membranes of the gastrointestinal tract.

Therefore, granulocyte differentiation and maturation process, as long as one of the links in the dysregulation can cause leukopenia.

A common cause is the reduction or maturation arrest of the granulocyte system in the bone marrow caused by various drugs. These drugs include chloramphenicol, synthroid, antithyroid drugs (propylthiouracil, tabazole), antipyretic and analgesic drugs (aminopyralid, soma pain, painkillers, anti-inflammatory pain, pau tazone, etc.), sulfonamides, antihistaminics, dondeleptin and triamcinolone acetonide, barbiturates and other sedatives, anti-tuberculosis drugs (isoniazid, p-amylsalicylic acid), antidiabetes (toluene sulfonylbutylamine), as well as a variety of antitumor drugs.

Next is liver disease, especially chronic hepatitis, when liver function can be normal. About half of the so-called unexplained primary leukopenia is actually caused by liver disease. Other causes include exposure to radioactive materials, dry hyperfunction, neonatal immunologic factors, and pancreatic insufficiency.

Leukopenia can also occur as a ****similar manifestation of aplastic anemia, preleukemia, megaloblastic anemia, paroxysmal sleep hemoglobinuria, iron-deficiency anemia, collagen disorders, acute leukemia, malignant histiocytosis, and infections of multiple causes. Anemia or thrombocytopenia can also be combined at this time.

For this reason, every patient with leukopenia should be further examined, the cause should be analyzed in detail, and the cause should be treated in order to be completely cured, otherwise it is easy to relapse.

Question 4: Briefly talk about the causes of low white blood cells and what are the dangers? First, the causes of low white blood cells

1, the impact of drugs

Some of the drugs will lead to a reduction in white blood cells, taking these drugs, pay attention to check the white blood cells, platelets, if the white blood cells are too low is too obvious, it should be discontinued or change the drug. Common drugs are: antibiotics; antitumor drugs and so on.

2, viral infections

Influenza, viral infections, viral hepatitis, etc. may lead to low white blood cells.

3, other diseases

A variety of solid tumor chemotherapy, a variety of blood diseases, immune system diseases and some chemical factors may cause low white blood cells.

Second, the harm of low white blood cells

1, easy to infectious diseases

White blood cells can quickly phagocytosis of foreign bodies and produce antibodies, effective resistance to pathogen invasion, and the immune aspect of the disease also has an important role. If the body's white blood cells are too low, it is prone to infectious diseases, and even fatal infectious diseases.

2, the decline in immunity, the body appears uncomfortable symptoms

Low white blood cells will make the body's immune system decline, there will be dizziness, fatigue, limb weakness, loss of appetite, hypothermia, insomnia and other non-specific symptoms, white blood cells, low part of the patient recurrent mouth ulcers, lung infections or urinary tract infections.

Third, how to treat low white blood cells

After clarifying the causes and hazards of low white blood cells, it is time to focus on solving this thorny problem. Some people may take white drugs, but as the saying goes, drugs are poisonous, although the effect of drugs quickly, but will also bring side effects to the human body. It may be worthwhile to take some supplements that elevate white blood cells. For example, initially by the Sanjiu Group funded the establishment of the Wuhan Jushengtang under the Sanjiu protein peptide, which is a small molecule protein with strong activity, the protein molecular weight segment between 200Da ~ 1000Da, are made up of 2 ~ 9 amino acids. It is directly absorbed without digestion after eating, and directly enters the circulatory system after absorption in the proximal part of the small intestine, and is utilized by the cell tissues to rapidly elevate the white blood cells. Timely intake, can quickly replenish the nitrogen source, synthesize human proteins, strong immune organs, enhance immune function.