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Can high white blood cells cause leukemia?

If there is inflammation in the body, there will be more white blood cells.

Having too many white blood cells does not mean it is leukemia. There are significantly more acute leukemias than chronic leukemias in China, about 5.6:1. Among adult acute leukemias, acute myeloid leukemia is the most common, and among chronic leukemias, chronic myeloid leukemia is the most common. Among the hematological characteristics of acute leukemia, the white blood cell count is variable. Those with increased white blood cell count are usually between (10-50)*10~9/L, and those exceeding 100*10~9/L are less common; there are also cases where the white blood cell count is within the normal range or less. Therefore, based on white blood cells alone, do not doubt that you have leukemia. To confirm leukemia, other things need to be looked at, including red blood cells and hemoglobin, platelet count and bone marrow imaging.

Diagnostic criteria for leukemia

1. Clinical symptoms include sudden high fever, progressive anemia or significant bleeding, and body aches and fatigue.

2. Signs: skin bleeding spots, sternum tenderness, lymph nodes, hepatosplenomegaly.

3. Laboratory:

A. Blood picture: White blood cells always increase (or decrease) significantly, and primitive or immature cells may appear.

B. If the bone marrow nucleated red blood cells account for less than 50 of the total nucleated cells and the blast cells are ≥30, acute leukemia can be diagnosed; if the bone marrow nucleated red blood cells account for ≥50 and the blasts account for the non-erythroid cells If the ratio is ≥30, acute erythroleukemia can be diagnosed.

Differential diagnosis:

A. Aplastic anemia;

B. Myelodysplastic syndrome;

C. Malignant tissue Cell disease;

D. Idiopathic thrombocytopenic purpura