1. Symptoms of colitis
(1) Diarrhea
Diarrhea is the main symptom of colitis in the early stage. Recurrent attacks are often induced by improper diet, emotional excitement and excessive fatigue. Due to inflammatory stimulation, the degree varies, ranging from 3 to 4 times a day, showing soft or mushy stool, which can be mixed with mucus and purulent blood; In severe cases, dozens of times or diarrhea and constipation appear alternately.
(2) Abdominal pain
Mild patients have no abdominal pain or only abdominal discomfort. Generally, there is mild to moderate abdominal pain, which is a pain in the left lower abdomen, and it can be related to the law that the whole abdomen can be relieved after defecation.
(3) constipation
constipation occurs once every 4-5 days, and the feces are like sheep feces. Even if you don't take laxatives, you can't relax.
Colitis is a chronic disease, and its symptoms are not easy to be found. Therefore, you should go to a professional hospital for examination and treatment as soon as the symptoms are found, so as not to regret it when the condition is serious.
2. Possible causes of colitis
1. Intestinal bacterial or viral infection
Inflammation of colonic mucosa in colitis is similar to some infectious diarrhea, such as bacillary dysentery and amebic dysentery, so it is suggested that the onset of colitis may be related to infection.
2. Genetic factors
The incidence rate of colitis varies greatly among different races, among which the incidence rate of white people is much higher than that of yellow people and black people; In addition, about 15%-3% of the immediate family members of patients with ulcerative colitis can have the same disease. It can be inferred that the incidence of colitis may be related to genetic factors.
3. Autoimmune factors
The occurrence of this disease is related to the autoimmune reaction, and it has been found from the observation of many patients with colitis that stopping eating certain foods can alleviate the condition; In addition, this disease also coexists with some immune diseases, such as erythema nodosum, purpura, nodular inflammation, drug allergy, etc. Adrenal hormone has a high therapeutic effect on this disease; Colon antibodies can be found in patients' serum, and many of the above phenomena indicate that the pathogenesis of colitis may be related to immune factors.
4. Excessive secretion of lysozyme
After some patients are infected with intestinal bacteria, the intestinal wall will secrete a large amount of lysozyme, which will dissolve the mucus in the intestinal wall, making the intestinal mucosa lose its protective layer and lead to the invasion of pathogenic microorganisms, and its lysozyme will decrease after recovery.
5. Neuropsychiatric factors
Mental factors play a certain role in the pathogenesis of colitis. Patients with colitis generally have certain personality characteristics, and people with poor psychological endurance and adaptability to major events in life are more likely to get sick.