Introduction: Due to different dosages, various drugs will form different compatibility with each other, thus producing different effects. This is a clear rule of Chinese medicine.

It is well known that changing the dosage of a prescription can alter its efficacy. Therefore, the prescribed dosage should be strictly required in clinical practice, and administration should not violate its regular schedule.

Common rules are summarized as follows:

High doses are the way to go to control the main effects.

A

In a prescription, there is an old saying, the one with the most medicine is the king. Jun medicine is designed to target the main causes and symptoms, and the dosage should be highlighted to ensure the direction of indications.

For example, in ephedra soup, the ratio of hemp to cinnamon is 3:2. This is the best ratio to ensure sweating and cannot be changed easily.

The Shiba Ma Si in Xing Shi Gan Tang and the Shi Ba Ma Liu in Yuemai Tang have profound meanings.

It is also a warming and tonic method, but different medicinal herbs in the prescription have different effects.

The focus of warming agent is dispersion. For example, Sini Decoction uses a large amount of aconite, and the pungent heat of dried ginger has the effect of restoring yang and breaking up yin to prevent adverse reactions. Therefore, there is a saying that "Aconite is not spicy and there is no ginger";

Evodia decoction treats syncope and yin-cold evils. Evodia warms and nourishes the liver and stomach, dispels cold and reduces inverse conditions, and is supplemented with ginger to cool down, dispel cold and calm inverse conditions. .

Wu and Tang Dynasties used Aconite to dispel cold and warm yang to treat cold water syndrome.

But the key point of warming tonics is tonic. For example, Lizhong Decoction treats Zhongjiao and cold deficiency, and cold arises from deficiency. Therefore, ginseng is the king of replenishing qi and strengthening the spleen, and dried ginger is the minister of dispersing cold and supporting yang, both of which have the effect of warming and tonifying middle yang.

The amount of warming medicine used in the warming powder method and the warming tonic method are different, and the status of the monarch and his ministers are different, so they should not be confused.

The dose should be determined based on the principle.

2

The one with the larger dose is the king. From the perspective of medicinal properties, functions and targeted causes, it belongs to the principle of active treatment. However, sometimes larger doses are prescribed for medical or therapeutic needs.

For example, Danggui Buxue Decoction mainly treats blood deficiency and fever. The ratio of astragalus to angelica is 5:1, with astragalus being the king. Although it is called Danggui Buxue Decoction, it actually uses astragalus to replenish qi and nourish the body to achieve the purpose of generating blood.

Qi and blood come from water and grains, and medicinal properties can only improve the body's water-soluble ability and ability to generate blood. Therefore, we must strengthen the nutrition of our diet, otherwise there is no hope of generating blood, which is in line with the saying "Visible blood is born from invisible Qi" " principle.

Another example is the principle of Shenqi Pills. Rehmannia glutinosa is first used to nourish the essence and blood, and Guifu is used less, resulting in the compatibility rule of "seeking yang from yin".

Also because of medical needs, large doses are not a royal medicine.

For example, a pound of raw rehmannia in Zhigancao soup is four times the dosage of the royal medicine licorice. For use by ministers and assistants only. It is determined based on the physiological characteristics of the heart and has been widely confirmed in modern clinical reports.

For example, using red blood powder to control the inflammation of heart fire, clearing fire and guiding red blood without bitter cold and purging heat, and using raw earth to strengthen water to control fire are also formulated based on the physiology and pathology of the heart.

Another example is liver meridian pain and diarrhea. Because the spleen is deficient and the liver is exuberant, Atractylodes macrocephala is used in the prescription, and the principle of "seeing liver disease, knowing the liver to generate spleen, and strengthening the spleen first" is used to treat the disease before it is cured.

Dosage can be flexibly changed and used according to symptoms.

Three

The drugs and dosages formulated by Party A are routine, and new rules will appear according to the increase or decrease of syndromes during use.

Take Guizhi Decoction as an example, the ratio of Guizhi Decoction