Contains a very small amount of fat trim. In a 260 gram fried sirloin steak, the fat content is about 25 grams and the calorie content is about 530 calories. By comparison, in the same weight of grilled sirloin steak, the fat content is about 17 grams and the calorie content is about 340 calories. The calorie and fat content of a sirloin steak can vary depending on how it is cooked and the quality of the meat.