As early as the Spring and Autumn Period and the Warring States Period, there were records about the medicinal use of wormwood. Zhuangzi said: "The more people smoke, the more they love it." . "On Mencius Li Lou" said: "I still have seven years of illness, and I want three years of love." It can be seen that as early as the Spring and Autumn Period, the efficacy of wormwood has been recognized.

Mencius' so-called "three-year wormwood" is a further understanding of the use of wormwood. Artemisia argyi preserved for 3-5 years not only eliminates dryness, but also retains medicinal properties, which is most suitable for moxibustion.

It is recorded in Fifty-two Diseases Prescription that burning wormwood is used to cure hemorrhoids. Folium Artemisiae Argyi is recorded in Treatise on Febrile Diseases, and the Jiao Tang Ai mentioned in it is still a gynecological prescription for treating blood deficiency and cold coagulation and menorrhagia. Ge Hong's Elbow Emergency Prescription in the Eastern Jin Dynasty stated that "moxibustion patients have four beds, one strong and the other strong, so that they will not be infected", that is, fumigation with mugwort leaves was used to prevent plagues and infectious diseases.

The famous doctor recorded that Artemisia argyi leaves were first used as medicine: "Artemisia argyi leaves taste bitter, slightly warm and nontoxic." The main moxibustion can cure all diseases, and can be used as decoction to stop diarrhea, hematemesis, lower sores, women's blood leakage, benefit Yin Qi, promote granulation, cover cold, and make life. "

In the Song Dynasty, Su Song mentioned in the Compendium of China Materia Medica that "Artemisia argyi leaves out of the ground and grows in the clouds. Today, everywhere, it is better to return to the Tao. This kind of moxibustion is especially good for any disease. " There is also a photo of Zhou Ming Ai Ye in the book. Tangyin county, Anyang, Henan, Siming, Ningbo, Zhejiang. For the first time, the book puts forward the authentic medicinal materials that pay attention to the quality of wormwood. "Biography of Artemisia argyi" is a monograph on Artemisia argyi, which describes that Artemisia argyi is "produced in Yangshan, used in the Dragon Boat Festival, and has made great contributions to treating moxibustion disease".

Li Shizhen was a physician who admired wormwood in Ming Dynasty, and his praise for wormwood was endless. His book Compendium of Materia Medica has done a lot of research and records on wormwood, including "Folium Artemisiae Argyi can cure all diseases by moxibustion" and "Moxibustion can pass through all meridians, and all those who cure all diseases and evils are regarded as Kangtai, and their achievements are also great." "Those who are deficient in abdomen and those who are afraid of cold in navel and abdomen are regarded as". Li Shizhen pointed out that mugwort "has been famous for mugwort since its formation, which is the most important thing in the world. It is said that moxibustion in other places is impenetrable, and moxa moxibustion is straight through, which is different. " Folium Artemisiae Argyi is an authentic medicinal material, which has been used ever since.