Bitter in nature; Xin; Gender equality; mild toxicity
The basic source of medicinal materials is the leaves of Acer truncatum, an Illicium plant.
Usage and dosage for external use: appropriate amount, fresh and mashed; Decocting and washing; Mo Yanshan.
Source: Chinese Materia Medica
Alias white dragon beard, white gold bar and white tendon bar.
Chinese pinyin bafengjiao root
English name Chinese Alangium root, the root of China azalea.
Latin names of plants, animals and minerals
1: octagonal maple. ) Harm [Stylosanthes. ]
2: octagonal maple. Et Zucc。 ) harm. Et Zucc。 ]
Meridian and liver; Kidney; Heart meridian of hand shaoyin
pharmacological action
(1) Muscle relaxation and analgesia: The total alkaloids extracted from the fibrous roots of Illicium verum can cause muscle relaxation in rabbits, rats, mice and dogs; Compared with succinylcholine, it takes effect slowly and lasts a little longer. During intravenous injection, there is a brief muscle tremor before muscle relaxation, similar to depolarizing muscle relaxants such as succinylcholine. Intravenous injection can obviously block gastrocnemius contraction caused by electrical stimulation of peripheral sciatic nerve in anesthetized rats. After intraperitoneal injection of decoction in mice, it can not only cause muscle relaxation, but also make the pain reaction disappear (hot plate method). Its medicinal part is fibrous root, which is about 3 times stronger than fine root and 5 times stronger than thick root. The effective components of muscle relaxation are mainly alkaloids; Glycosides have little effect. The combination of Illicium verum and Anning (aminopropyl ester) can fully relax the muscles of the limbs of rabbits and dogs, and the righting reflex disappears, but the righting reflex cannot disappear when the two drugs are used alone, which shows that the two drugs have synergistic effect.
(2) Contraceptive effect: Mice have obvious anti-early pregnancy and anti-implantation effects after 4-6 days of oral administration.
(3) Effect on myocardium and smooth muscle: Generally, the water decoction of Illicium verum L. or total alkaloids have no obvious effect on isolated toad heart, isolated rabbit heart or in vivo rabbit heart, but a large dose has inhibitory effect. Total alkaloids can also enhance the rhythmic contraction of isolated rabbit intestine, and clinical application will not cause intestinal paralysis. It can also enhance the contraction of isolated rabbit uterus.
(4) Effects on heart, blood pressure and respiration: Intravenous injection of fibrous root decoction 1.25- 1.5g/kg or total alkaloid of Illicium verum can cause respiratory depression, even gradually stop. At this time, when the chest cavity is cut open, it can be seen that the heart has atrioventricular block, and the heartbeat can still be maintained for about half an hour after breathing stops. Anesthetized rabbits were injected with total alkaloids of Illicium verum 1- 1.8mg/kg, and their breathing became temporarily excited, and their breathing amplitude increased, at this time, their blood pressure decreased briefly. When the dose was 2mg/kg, breathing slowed down, weakened or even stopped, and blood pressure gradually decreased. If artificial respiration is performed, blood pressure can still rise.
The chemical constituents of traditional Chinese medicine are obtained from the dried roots, stems and branches of Erigeron, namely camptothecin and dl- Ambroxine [1], which contain β-coumarin acetate, triacontanol and β-sitosterol.
Two alkaloids [1], camptothecin and dl- equisetine, were isolated from the dried roots, stems and branches of melon.
The effect of expelling wind and removing dampness; Relaxing tendons and activating collaterals; Removing blood stasis and relieving pain
Textual research originated from materia medica from the beginning.
Classification of families and genera: Illicium.
Latin name Radix Alang II China
Pharmacology (toxicology)
The minimum lethal dose and muscle relaxation of total alkaloids in Dysosma versicolor were 5.65 mg/kg and 2.47mg/kg, respectively, and the ratio of them was 2.28: 1, while succinylcholine was 1.5: (1). Although the muscle relaxation strength of this product is weaker than the latter, its safety range is wider. Intravenous injection of total alkaloids from Illicium verum can temporarily excite breathing in anesthetized rabbits or dogs, and increase the dose will stop breathing. When breathing is exciting, the blood pressure of rabbits will decrease and that of dogs will increase. If artificial respiration is performed, the dose that leads to respiratory arrest has little effect on blood pressure and heartbeat. Intravenous injection of acidic alcohol extract 0. 1g/kg in cats significantly reduced blood pressure, and the lethal dose was about 4g/kg. Moderate dose can cause hematuria, adrenal hemorrhage and muscle tremor. Large doses can increase saliva secretion, so be careful when combined with ether. According to folklore, radish seed can save the acute poisoning of Illicium verum, but in animal experiments, radish seed, atropine, nikethamide, Huisuling and neostigmine can't save the respiratory depression of Illicium verum, so artificial respiration must be used to save it. Rabbits were injected with 1.9mg/ kg total alkaloids of Illicium verum or 10 g/kg fibrous root decoction intravenously every day for *** 15 days, which had no obvious effect on body weight and electrocardiogram, and white blood cells seemed to increase. The retention rate of sodium sulfobromophthalein in oral group seems to increase; Phenol red excretion has no obvious effect. Pathological anatomy There was mild focal inflammation in the kidney of intravenous injection group, and no special manifestations were found. The root and stem bark of the same plant Alangiumlamarckii contain Alangine with parasympathetic function.
Subacute toxicity: rabbits were given total alkaloids of Dysosma versicolor 1.9mg/kg intravenously, or fibrous root decoction 10g/kg intragastrically for 15 days. Results The cholestasis rate of most animals in the gavage group increased, which had certain influence on liver function. The kidneys of the animals in the intravenous administration group had mild focal inflammation, and the livers of both groups had mild steatosis, mild inflammation or focal necrosis.
Indications of rheumatism and joint pain; Numbness of limbs; Injuries caused by falls and collisions
The ecological environment is born in mountainous areas or sparse forests below the altitude of1800 m. Born in hillside or sparse forest below 2000 meters above sea level.
It can be harvested and stored all year round. Branches or fibrous roots can be dug up, washed and dried.
Party selection
1: Treatment of rheumatic numbness: platinum bars, 2.50 for men and 1.50 for women. The wine has been soaked for six liang. It costs five yuan to take medicine and drink every time.
2. Treatment of rheumatic numbness and paralysis: 1. Two dollars for platinum bars, San Qian's hemp, and one or two dollars for cabbage. Stewed meat to eat. 2. One yuan for white dragon, four yuan for wild vegetables and half a catty for pork. Chop up the medicine and stew it at once. (After taking it 12 hours, I feel numb and sweaty, and my hands and feet are weak. )
3. Cure crane knee wind: five dollars for platinum bars, San Qian for Songjie, San Qian for red and white Achyranthes bidentata. Cut into pieces and soak a catty of soju. The medicinal liquor is five yuan each, which is taken regularly.
4. Treatment of low back pain due to strain: two dollars for platinum, one or two for Achyranthes bidentata (fried with vinegar) and one or two for Eucommia ulmoides Oliv. Six taels of wine per person, fried and served.
5. Treatment of hemiplegia: platinum bar is one yuan and fifty cents. Steamed chicken to eat. (1. The following are Guiyang folk herbs)
6. Treatment of traumatic injury: two yuan for the root of octagonal maple, five yuan for the root of abacus and one or two for acanthopanax senticosus. Soak clothes. (Guizhou herbs)
7. Treatment of nosebleeds: two dollars of platinum bars. Decoct with water. (Guizhou folk prescription and drug collection)
Contraindications: pregnant women, children and the elderly and infirm should not take it. You should avoid eating fish after taking this medicine. This medicine is very toxic and will paralyze people. After taking it, it will cause paralysis and weakness, and pregnant women should not take it.
Adverse reactions and side effects of treatment: People who take too much medicine (4-6.5 yuan) may have nausea and vomiting. Dizziness and fatigue can disappear after atropine injection. There was 1 case of transient blurred vision, which was cured without treatment.
Classification of efficacy of wind-dispelling drugs; Huoxue medicine; Medicine for treating rheumatism