Most people think that gout medicine does not have serious side effects, but this is not the case. In recent years, there have been many reports of serious side effects caused by gout drugs. At the Athens Olympics, taking gout drugs caused kidney failure and had to bid farewell to the Olympics. In the end, he had to embark on a kidney transplant to get rid of the pain of long-term kidney dialysis. Gout itself does not cause uremia or renal failure, but gout drugs can cause serious damage to the liver and kidneys, causing uremia and renal failure.

Due to the side effects of drugs, they have to be taken precautions. The prevention method is to pay attention to some clues before a certain side effect occurs, that is, warning symptoms. If you stop using or switch to other drugs and treatments at this time, serious side effects can be avoided. The following are possible side effects of anti-gout medications.

The gout drug colchicine

is an essential drug for general gout patients, and its side effects usually include:

1. Gastrointestinal symptoms: abdominal pain, diarrhea, watery stool, vomiting and loss of appetite are common early adverse reactions, with an incidence rate of up to 80%. In severe cases, dehydration and electrolyte imbalance may occur Wait for performance. Long-term users may develop severe hemorrhagic gastroenteritis or malabsorption syndrome.

2. Muscle and peripheral neuropathy: manifested as numbness of hands and feet, soreness of limbs, muscle spasm, tingling, weakness, ascending paralysis, etc., which can cause depression of the respiratory center and death. Myoneuropathy is rare in clinical practice and often occurs in people who take it for a long time to prevent gout and those who have mild renal insufficiency.

3. Bone marrow suppression: Long-term use of colchicine to suppress bone marrow hematopoietic function is a common manifestation of poisoning, which can cause thrombocytopenia, neutrophil decline, and even aplastic anemia. Typical cases occur on the 3rd to 5th day after taking the drug and last for more than a week. They are often accompanied by multiple organ failure and sepsis, and the mortality rate is high.

4. Teratogenicity: This drug can inhibit the normal division of cells. Both fathers had a history of long-term use of colchicine due to familial Mediterranean fever.

5. Kidney: oliguria, proteinuria, hematuria, ketonuria, and even renal fatty degeneration.

6. Others: palpitations, fever, hair loss, myasthenia gravis, liver damage, pancreatitis, rash, taste disorder, etc. If the drug is administered by injection, local tissue necrosis may occur when the drug liquid leaks out of the blood vessel.