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Introduction of Pueraria Mirifica
Table of Contents 1 Pinyin 2 English Reference 3 Overview 4 Latin Name 5 English Name 6 Alias of Pueraria Mirifica 7 Source 8 Place of Origin 9 Sexual Flavor and Meridian 10 Efficacy and Indications of Pueraria Mirifica 11 Usage and Dosage of Pueraria Mirifica 12 Chemical Composition of Pueraria Mirifica 13 Pharmacological Actions of Pueraria Mirifica 14 Alias of Pueraria Mirifica 15 Consumption Value of Pueraria Mirifica 15.1 Tips on the Use of Pueraria Mirifica 15.2 Nutritional Value of Pueraria Mirifica 15.3 Suitable Crowd of Pueraria Mirifica 15.4 15.5 Suggestions on the Consumption of Pueraria Mirifica 16 Pueraria Mirifica Poisoning 16.1 Mechanisms of Adverse Reactions 16.2 Symptoms of Pueraria Mirifica Poisoning 16.3 Treatments 17 Codex Standards for Pueraria Mirifica 17.1 Name 17.2 Origin 17.3 Properties 17.4 Identification 17.5 Examination 17.5.1 Moisture 17.5.2 Total Ash 17.6 Leachate 17.7 Determination of Contents 17.7.1 Chromatography 17.7.1 Chromatographic conditions and system suitability tests 17.7.2 Preparation of control solution 17.7.3 Preparation of test solution 17.7.4 Assay 17.8 Beverages 17.8.1 Concoction 17.8.2 Examination 17.8.2.1 Moisture 17.8.2.2 Total ash 17.8.3 Identification, leachate, and determination of content 17.8.4 Flavors and attribution 17.8.5 Functions and indications 17.8.6 Usage and Dosage 17.8.7 Storage 17.9 Origin 18 References Attachment: 1 Formulas using Pueraria Mirifica 2 Proprietary Chinese Medicines using Pueraria Mirifica 3 Pueraria Mirifica in Ancient Texts * Pueraria Mirifica Drug Description 1 Pinyin

gě gēn

2 English Reference

radices puerarire [Landau Chinese-English Dictionary]

kudzuvine root [朗道汉英字典]

Radices puerarire [朗道 Chinese-English Dictionary]. kudzuvine root [Xiangya Medical Dictionary]

puerariae,radix [Xiangya Medical Dictionary]

puerariae,radix [Xiangya Medical Dictionary]

radix puerariae [Xiangya Medical Dictionary]

the root of kudzu vine [21st Century English-Chinese-Chinese-English Two-Way Dictionary]

Radix Puerariae (拉) [Nomenclature Review Committee of Chinese Medicine. Chinese Medicine Nomenclature (2004)]

kudzuvine root [Chinese Medicine Nomenclature Validation Committee. Nomenclature of Chinese Medicine (2004)]

3 Overview

Pueraria Mirifica

Pueraria Mirifica is the name of the traditional Chinese medicine (TCM), which is derived from the Divine Husbandman's Classic of the Materia Medica (DHCM). It is the dried root of Pueraria lobata (Willd.) Ohwi or Pueraria thomsonii Benth, family Leguminosae[1].

4 Latin name

Radix Puerariae (La) (Nomenclature of Chinese Medicine (2004))

5 English name

kudzuvine root (Nomenclature of Chinese Medicine (2004))

6 Alias of Pueraria lobata (Pueraria lobata)

Glycyrrhiza glabra, Glycyrrhiza glabra[2].

7 Source

Pueraria lobata (Willd.) Ohwi, legume, or the dried root of Pueraria thomsonii Benth, sweet kudzu vine [1].

Pueraria lobata (Willd.) Ohwi or Pueraria thomsonii Benth. root [2].

8 Origin

Pueraria lobata (Willd.) Ohwi or P. thomsonii Benth. is mainly produced in Henan, Hunan, Zhejiang, Sichuan and other places [2].

9 Flavor

Pueraria lobata has a sweet, pungent taste and flat nature; it enters the spleen and stomach meridians [2].

10 Pueraria lobata efficacy and treatment

Pueraria lobata has the efficacy of relieving muscle fever, transmitting rash, generating fluids, and stopping diarrhea[2]:

Pueraria lobata treats cold and fever, headache, headache, strong collar, measles, poor transmitting, fever and thirst, diarrhea, dysentery[2].

Pueraria Mirifica treats strong neck pain caused by hypertension, angina pectoris of coronary heart disease, myocardial infarction, cerebral thrombosis, early sudden deafness [2].

Pueraria lobata is a starch taken by water milling and clarification of the name of Pueraria lobata, taken internally for the treatment of irritable heat, thirst [2].

Pueraria lobata is commonly used in ophthalmology to dispel wind and clear heat, and has the effect of releasing and relieving muscle, relieving heat and promoting Yang Qi:

(1) It is used for orbital pain and frontal headache caused by ophthalmological diseases, and is often used with Angelica dahurica, Qiangwu, and Chaihu.

(2) For Yangming meridian head wind headache, body heat and thirst, often with Angelica dahurica, ascending hemp, gypsum, such as ascending hemp dahurica Ge Tang.

(3) Used to elevate the spleen yang, inspire the stomach qi upward, often used with ginseng, astragalus, etc., the treatment of spleen and stomach insufficiency, cataracts, tinnitus, or for many years the eyes dim, vision can not.

Modern pharmacological research shows that this product contains flavonoid glycosides (mainly Puerarin), can dilate blood vessels, increase cerebral and coronary blood flow, can improve microcirculation, and has a hypoglycemic effect. Therefore, it is widely used for ischemic lesions of the fundus.

11 Usage and dosage of Pueraria Mirifica

Decoction, 6-15g[2].

It is suitable for simmering in spleen deficiency and diarrhea[2].

12 Chemical composition of Pueraria Mirifica

Pueraria Mirifica root contains wild kudzu glycosides (Pueroside) A and B, Puerarin, Puerarin xyloside, soybean, soybean glycosides and other flavonoids, β-sitosterol, arachidonic acid and so on [2].

13 Pharmacological effects of Pueraria Mirifica

Total flavonoids and puerarin can increase coronary blood flow in dogs, and can significantly increase cerebral blood flow, vascular resistance decreased [2].

Puerarin significantly limits the extent of experimental acute myocardial infarction in dogs [2].

Pueraria lobata alcoholic extract and puerarin have anti-experimental arrhythmic effects [2].

Pueraria Mirifica alcoholic extract has antagonized the myocardial ischemic response induced by pituitary posterior lobe hormone in rats; and has antipyretic effects in rabbits with artificial fever[2].

Pueraria Mirifica is also antihypertensive, prevents atherosclerosis, and resists platelet aggregation and formation [2].

Pueraria Mirifica components also lower blood lipids, improve memory function, anti-tumor, antioxidant and other effects [2].

Soybeanin has an antispasmodic effect on the smooth muscle of the intestinal tubes and also lowers blood sugar [2].

A decoction of Pueraria Mirifica inhibits dysentery bacilli in vitro [2].

14 Alias of Pueraria Mirifica

Pueraria Mirifica, Powdered Kudzu, Wild Kudzu, Wild Kudzu Vine, Kudzu Strips, Powdered Kudzu Teng

Dried Kudzu, Powdered Kudzu, Pueraria Mirifica Roots, Kudzu Vine, Yellow Kudzu Roots [3].

15 Edible value of Pueraria Mirifica

Pueraria Mirifica is the root of the legume Pueraria Mirifica, a perennial plant of the genus Pueraria, family Leguminosae. Its root is both the ancient rescue plant, but also the motherland medicine commonly used in traditional Chinese medicine. Born in the grassy mountain slopes, roadsides, sparse forests in the more shady and moist place. Mainly produced in Hunan, Zhejiang, Henan, Guangdong. Autumn, winter digging, while fresh cut into thick slices or small pieces, dry. Spring planting winter harvest, containing a lot of starch, Jiangmen people used to boil soup, cooking, starch consumption.

15.1 Pueraria Mirifica Tips

About 80 grams per meal

15.2 Pueraria Mirifica Nutritional Value

Pueraria Mirifica mainly contains carbohydrates, vegetable proteins, a variety of vitamins and minerals, in addition to flavonoids: Soya bean pigment, soybean glycosides, as well as Soya bean pigment 4,7 diglucoside, Pueraria Mirifica, Pueraria Mirifica 7 xyloside, Pueraria Mirifica, Pueraria Mirifica, and isoflavone glycosides, etc.

1.

1. Nutrition of the myocardium, dilate blood vessels Pueraria lobata total flavonoids and Puerarin can improve myocardial oxygen metabolism, myocardial metabolism has a beneficial effect, at the same time can dilate the blood vessels, improve microcirculation, reduce vascular resistance, so that the blood flow increased, so available to prevent and control myocardial ischemia, myocardial infarction, arrhythmia, hypertension, arteriosclerosis and other diseases.

2. Release the muscle Acetone extract of Pueraria Mirifica has the effect of restoring the body temperature to normal, and is effective in a variety of fever. Therefore, it is often used in fever and thirst, upset and other diseases.

3. Hypoglycemic and hypolipidemic Pueraria Mirifica has a significant role in lowering blood sugar, Pueraria Mirifica contains flavonoids have hypolipidemic effect, can lower serum cholesterol, reduce triglycerides, used in the treatment of hyperglycemia, hyperlipidemia, have significant therapeutic effects.

4. Pueraria Mirifica Some studies have shown that Pueraria Mirifica has a clear course of therapeutic effects on learning and memory disorders, and Pueraria Mirifica alcoholic extracts can significantly counteract the memory impairment caused by the east of alkaloids. It can be used to treat Alzheimer's disease, mental retardation, poor memory and other conditions.

5. Lift the yang qi, quench thirst and stop diarrhea Pueraria Mirifica is light and clear, the medicinal properties of the rise, the willow lifting the yang qi, encouraging the body positive qi rise, fluid cloth line. Ascension of the spleen and stomach clear Yang air and thirst, diarrhea and diarrhea. Therefore, it is often used in the treatment of internal heat and thirst, measles, diarrhea, dysentery and other diseases.

15.3 Pueraria Mirifica suitable for the crowd

The general population can be consumed.

15.4 The therapeutic efficacy of Pueraria Mirifica

Pueraria Mirifica is sweet, pungent, and cool, and belongs to the spleen and stomach meridian;

It has the efficacy of relieving muscle fever, generating fluids, transmitting rashes, and elevating yang and stopping diarrhea;

It is mainly used in treating exogenous fever, headache and obstinacy, thirst, thirst, impenetrability of measles, hot dysentery and diarrhea; and hypertension, neck and neck pain, and other conditions.

15.5 Suggestions for Pueraria Mirifica

1. Cinnamon Pueraria Mirifica Soup Cinnamon sugar 5 grams, Pueraria Mirifica 50 grams. First of all, use cool water to mix the powder, then use boiling water to melt the powder, so that it becomes crystal clear, add people cinnamon sugar mix evenly that is to become. This soup is sweet and moist, fragrant odor. This soup has the effect of delaying heat and generating fluids, relieving the muscle published, applicable to fever, thirst, heartburn, mouth and tongue ulcers and other diseases.

2. Pueraria lobata porridge Pueraria lobata 200 grams, 300 grams of corn. Soak corn with water overnight, the next day splash, and kudzu powder with mixing evenly, according to the normal method of cooking porridge, porridge into the discretionary seasonings. This porridge is soft and smooth, fragrant and refreshing the spleen, with nutritional organism, when the efficacy of Yang Qi, applicable to the prevention and treatment of cardiovascular and cerebrovascular diseases. High blood pressure, diabetes, diarrhea, dysentery patients should always eat.

3. 200 grams of kudzu powder rice, Liang corn rice 500 grams. First with boiling water will be wet rice, add people Pueraria lobata mix well, put people drum juice water appropriate amount, cooked on the fire. Properly mixed with seasonings can be eaten. This rice has the effect of clearing the mind and waking up the spleen and promoting intelligence. Apply to mania, mind drifting speech disorder, memory loss and other conditions.

4. Pueraria lobata pig pancreas soup Pueraria lobata 50 grams, pig pancreas half. The pig pancreas will be washed and cut into thin slices, decoction water, when the pig pancreas is cooked, add people Pu powder mixing, discretionary flavor seasoning, can be consumed. This soup is fresh and flavorful, with the efficacy of the thirst, lowering sugar, suitable for the treatment of thirst, polyuria and other diseases.

16 Pueraria lobata poisoning

Pueraria lobata contains a large number of flavonoids and Puerarin [3]. The main pharmacological effects are to improve coronary circulation, dilate cerebral blood vessels, antihypertensive, hypoglycemic, hypolipidemic, antiplatelet agglutination, antipyretic, relaxation of gastrointestinal smooth muscle, and puberty [3].

16.1 Mechanisms of adverse reactions

The incidence of adverse reactions to intravenous drip is only 4%. Occasionally, allergic reactions, too much or too long to take Puerarin lead to accumulation in the body, through the blood-cerebrospinal fluid barrier into the brain tissue, the role of the hypothalamic thermoregulatory center, causing fever. [3]

16.2 Symptoms of Pueraria Mirifica poisoning

Pueraria Mirifica poisoning manifests as panic, irritability, gradual reddening of the face, nausea, abdominal distension, tightness in the chest, shortness of breath and allergic reactions such as rash, itching, and there are also hemolytic reactions, elevation of aminotransferases, renal colic and so on. Fever occurs more often with intravenous drip. [3]

16.3 Treatment

The main points of treatment of Pueraria lobata poisoning are [3]:

1. Symptomatic treatment ? For those with fever, antipyretic drugs such as Chai Hu and Analgin can be used to lower the temperature; for those with allergic reactions, anti-allergic drugs should be applied.

2. Prevention ? 1 week course of treatment, rest for a few days before using the drug, do not prolong intravenous drip.

17 The canonical standard of Pueraria lobata 17.1 Name

Pueraria lobata

Gegen

PUERARIAE LOBAMLE RADIX

17.2 Source

This product is the dried root of the legume Pueraria lobata (Willd.) ohwi. It is habitually called kudzu. Autumn, winter two seasons digging, while fresh cut into thick slices or small pieces; dry.

17.3 Properties

The product is longitudinally cut into thick rectangular slices or small cubes, 5-35cm long, 0.5-lcm thick, the outer skin is light brown, longitudinal wrinkles, rough. The cut surface is yellowish-white, and the texture is not obvious. The texture is tough and fibrous. Gas slightly, taste slightly sweet.

17.4 Identification

(1) The powder is light brown. The starch granules are spherical, 3-37 μm in diameter, umbilical dotted, fissured or stellate; the compound granules are composed of 2-10 grains. Fibers are mostly bundled, thick-walled, lignified, and most of the surrounding cells contain calcium oxalate square crystals, forming crystal fibers, and the walls of the crystal-containing cells are lignified and thickened. The stone cells are rare, rounded or polygonal, 38-70 μm in diameter, and the ciliated ducts are large, with ciliated pores hexagonal or elliptic, and extremely tightly arranged.

(2) Take 0.8g of powder, add 10ml of methanol, leave for 2 hours, filtration, filtrate evaporation, residue add 0.5ml of methanol to dissolve, as a test solution. Another take Pueraria Mirifica control herb 0.8g, the same method into a control herb solution. Then take Puerarin control, add methanol to make a solution containing 1mg per 1ml, as the control solution. According to the thin-layer chromatography (2010 Pharmacopoeia, Appendix VI B), absorb the above three solutions of 10μl, respectively, point in the same silica gel G thin-layer plate, so that the strip, with trichloromethane-methanol-water (7: 2.5: 0.25) as an unfolding agent, unfolding, take out, drying, and placed in the ultraviolet lamp (365nm) to check. In the chromatogram of the test product, in the corresponding position with the chromatogram of the control herb and the chromatogram of the control product, the fluorescent streaks of the same color.

17.5 Check 17.5.1 Moisture

Not more than 14.0% (2010 version of the Pharmacopoeia, Appendix IX H, the first method).

17.5.2 Total ash

not more than 7.0% (2010 version of the Pharmacopoeia, Appendix IX K).

17.6 Leachate

According to the alcohol-soluble leachate method (2010 version of the Pharmacopoeia, Appendix V A) under the item of hot leaching method, with dilute ethanol as a solvent, not less than 24.0%.

17.7 Content determination

Determined by high performance liquid chromatography (2010 version of the Pharmacopoeia, Appendix VI D).

17.7.1 Chromatographic conditions and system suitability test

Octadecylsilane-bonded silica gel as filler; methanol and water (25:75) as the mobile phase; detection wavelength of 250 nm; the theoretical number of plates according to the calculation of Puerarin peaks should not be less than 4000.

17.7.2 Preparation of the control solution

Puerarin control appropriate amount of precise weighing, add 30% ethanol to make 80% of each 1ml. Ethanol to make a solution containing 80μg per 1ml, that is obtained.

17.7.3 Preparation of test solution

Take the product powder (sieve No. 3) about 0.1g, precision weighing, placed in a stoppered conical flask, precision add 30% ethanol 50 ml, weighing, heating reflux for 30 minutes, cooled, and then weighing, 30% ethanol to make up for the loss of weight, shaking, filtration, and then filtrate, i.e., obtained.

17.7.4 Determination method

Precisely absorb the control solution and test solution 10μl each, injected into the liquid chromatograph, determination, that is obtained.

This product is calculated according to the dry product, containing Puerarin (C21H20O9) shall not be less than 2.4%.

17.8 Drinking tablets 17.8.1 Concoction

Remove impurities, wash, moisten, cut thick slices, sun dry.

The product is irregular thick slices, thick silk or square with side length of 5-12mm. Cut surface light yellow-brown to brown-yellow. Tough, fibrous. Slight gas, slightly sweet flavor.

17.8.2 Inspection 17.8.2.1 Moisture

The same as the herbs, not more than 13.0%.

17.8.2.2 Total ash

The same herbs, not more than 6.0%.

17.8.3 Identification, leachate, content determination

Same as the herbs.

17.8.4 Flavor and attribution

Sweet, pungent, cool. Attributes to the spleen, stomach and lung meridians.

17.8.5 Functions and Indications

Relieving muscle fever, promoting the production of body fluid to quench thirst, penetrating rashes, promoting Yang and stopping diarrhea, activating the channels and detoxifying alcohol. It is used for external fever and headache, strong pain in the neck and back, thirst, thirst, impenetrable measles, hot diarrhea, diarrhea, dizziness and headache, hemiplegia, chest paralysis and heart pain, and wine poisoning.

17.8.6 Usage and dosage

10~15g.

17.8.7 Storage

In a ventilated dry place, prevent moth.

17.9 Existence

Chinese People's Pharmacopoeia 2010 Edition

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