Second, they have different functions. Amoxicillin is a broad-spectrum antibiotic, which has a strong antibacterial effect on gram-negative bacilli. It is mainly used to treat respiratory tract, urinary tract and biliary tract infections caused by sensitive bacteria and typhoid fever, and has strong antibacterial effect on Helicobacter pylori. Cephalosporins can be divided into four generations. The first generation is mainly cefradine, which is effective for staphylococcus and staphylococcus aureus. Cefuroxime, commonly used in the second generation, has obvious effect on gram-negative bacteria; The third generation is ceftriaxone and cefixime, which are effective for gram-negative bacteria and basically non-toxic to kidneys; The fourth generation is cefradine and cefepime, which are highly effective against most gram-negative bacteria and some gram-positive bacteria and have no nephrotoxicity.