Dependence may not exist, but long-term use will lead to drug resistance, which means that eating too much may not be so effective. It is recommended to change the medicine frequently, but before changing the medicine, you should see clearly what medicine can and can't be taken. Generally speaking, urticaria is impossible to cure, and it can relieve symptoms at most. Because this disease is very common and has little effect on human organs, most doctors will not care too much. But urticaria is caused by low body resistance, which means that it has been accompanied when it appears. Short-term use of cetirizine hydrochloride is no problem, but it often makes people sleepy, dry mouth, weak body and slow brain response. I don't know if it will affect people's brains, but I suggest not to use too much. The upgraded version of cetirizine hydrochloride and levocetirizine hydrochloride has much less side effects, and its efficacy is six times that of cetirizine. You can try. This is a prescription. Doctors have to write a prescription to get the medicine. If you want to cure the disease, it is recommended to improve your immunity and exercise more. In any case, more exercise is always beneficial.