Causes of aggravation of urticaria pruritus at night;
1, decreased hormone secretion
The secretion of hormones is the most in the morning, but relatively less at night, and its function of inhibiting the release of allergic mediators is weakened. At night, the inhibitory effect of hormones on urticaria will be significantly weakened, so urticaria is often severe at night.
2, the role of the nervous system
People are often in a state of vagus nerve excitation and sympathetic nerve inhibition during sleep, while vagus nerve dominates and acts on bronchial smooth muscle. The increased excitement of vagus nerve will cause the contraction of bronchial smooth muscle, which will cause the spasm of bronchial smooth muscle, narrow airway and difficulty in exhaling.
3. Allergic factors increase.
Patients with urticaria will come into contact with pillows, quilts and other supplies when they sleep, and these supplies often contain some debris, which is easy to hide some bacteria or particles, which can easily aggravate the symptoms of patients with urticaria, thus making urticaria attack at night. Therefore, the increase of allergic factors at night will make urticaria attack at night.
4, the human body function is weakened
The main reason of urticaria itching at night lies in the weakening of human function at night, slow blood flow and lack of skin nutrition, so itching is heavier at night.
5, human sensitivity is enhanced.
At night, people are less active, less disturbed by the outside world, sensitive to their own changes, and itchy.
6, the influence of outside temperature
The temperature at night is relatively low, and the respiratory tract inhales air with temperature, which leads to the disorder of bronchial smooth muscle relaxation and contraction, which aggravates the situation of asthma and suffocation.
7. When people sleep at night, the mechanical sensation function of the chest is weakened, and the airway secretions are not discharged smoothly. Blocking or stimulating the airway can cause the onset of wheezing, and after sleep, the airway is in a state of natural or fatigue relaxation, and sputum is deposited, blocking the airway and causing laryngeal obstruction.
Correctly deal with urticaria and keep these four points in mind.
1. Mild urticaria can be relieved by drinking water.
Mild urticaria can promote the discharge of allergens by drinking plenty of water, thus achieving the purpose of "self-healing" of urticaria.
2. Avoid excessive stimulation of the affected area when the disease occurs.
Patients with urticaria should avoid using irritating skin cleaning products such as soap, and try to reduce scratching to avoid aggravating the rash.
In addition, local cold and wet compress of rash, or topical lotion can relieve itching.
3. Rational use of antiallergic drugs under the guidance of doctors.
It is suggested that after consulting your doctor, you can always keep some antihistamines at home, such as loratadine and cetirizine. But pay attention to whether there are any contraindications before taking the medicine. In addition, calcium gluconate and vitamin C have certain antiallergic effects.
4. Immune regulation such as Xinminkang probiotics can be selected to reduce the individual differences of allergic constitution, reduce the IgE allergic antibody in serum, and regulate the TH2 immune response overreacted due to allergy by enhancing the TH 1 type immune response, so as to enhance the anti-allergic ability in vivo, adjust the allergic constitution and prevent various allergic diseases. The imbalance of five kinds of immunoglobulin secretion in human body is the fundamental cause of the disease. At present, the treatment method of IgE anti-human antibody to solve urticaria in international immunology research is to supplement Xinminkang probiotics to reduce IgE antibody in the body, and regulate the balance of immunoglobulin by stimulating interferon secretion, so as to restore the human immune response correctly.